Mutation

List of causal flows influenced by the mutation.

Causal Flows are statistically significant links between putative causal events (somatic mutations, copy number variations, chromosomal translocations, etc.) and the activity levels of regulators and regulons. In the causal flow, a mutation may causally activate or deactivate a downstream regulator which then might up- down-regulates a regulon that contains genes with similar expression profiles and binding sites.

Causal Mechanistic Flows for Mutation MYC

RegulatorRoleRegulonCox Hazard Ratio (Regulon)Transcriptional Programs
SPI1down-regulatesR-26190.0114715Pr-3
TFEBdown-regulatesR-8890.0284888Pr-39
PAX6up-regulatesR-15560.0296134Pr-117
HOXD1down-regulatesR-1302-0.0406426Pr-137
ENSG00000054598down-regulatesR-1002-0.0418558Pr-14
ESRRAup-regulatesR-27470.0501381Pr-35
ENSG00000245848down-regulatesR-16550.0553209Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

STAT3down-regulatesR-311-0.0731142Pr-135
NFYCdown-regulatesR-2950.112035Pr-4
TP53up-regulatesR-3760.127114Pr-38
ETV5down-regulatesR-3420.139146Pr-117
JUNdown-regulatesR-11850.14361Pr-118
SPI1down-regulatesR-2610-0.164598Pr-117
ZBTB3up-regulatesR-12670.175091Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

TP53up-regulatesR-373-0.181773Pr-130
THRAdown-regulatesR-620.204827Pr-117
NF1down-regulatesR-127-0.22305Pr-18
ETS2down-regulatesR-19040.237053Pr-117
ZBTB3up-regulatesR-1266-0.259836Pr-117
POU2F1down-regulatesR-77-0.259838Pr-14
HLXdown-regulatesR-27640.260576Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

POU2F1down-regulatesR-83-0.310208Pr-41
TFE3down-regulatesR-558-0.31956Pr-39
XBP1down-regulatesR-30590.341163Pr-35
HMGA1up-regulatesR-817-0.342996Pr-58
SPI1down-regulatesR-2601-0.345541Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

MAFBdown-regulatesR-1748-0.346189Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

ZFXdown-regulatesR-1927-0.36742Pr-5
IRF8down-regulatesR-26340.369682Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

PAX6up-regulatesR-1545-0.374773Pr-14
NF1down-regulatesR-1300.381224Pr-109
TP53up-regulatesR-369-0.383401Pr-117
HMGA1up-regulatesR-8320.407077Pr-119

Genes (4)

GPBAR1, RHD, GMFB, C5AR1

Regulons (4)

R-832, R-1181, R-58, R-164

ZBTB3up-regulatesR-1275-0.421961Pr-3
KLF4down-regulatesR-2758-0.426292Pr-129
CEBPDdown-regulatesR-1312-0.440834Pr-126
ZFXdown-regulatesR-1917-0.446489Pr-6
HINFPup-regulatesR-2624-0.44835Pr-35
BCL6down-regulatesR-5460.459576Pr-120
KLF4down-regulatesR-27530.461265Pr-60
JUNdown-regulatesR-11770.50809Pr-138
E2F2up-regulatesR-2943-0.530398Pr-58
MAFGdown-regulatesR-14950.551417Pr-117
XBP1down-regulatesR-30520.559099Pr-108
MAFBdown-regulatesR-17390.566253Pr-128
ENSG00000245848down-regulatesR-16420.576599Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

ZNF143up-regulatesR-2309-0.580912Pr-2
MAFdown-regulatesR-1090.590988Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

ZBTB3up-regulatesR-12700.603274Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

JUNdown-regulatesR-11750.678783Pr-137
USF1down-regulatesR-1857-0.686447Pr-39
SPI1down-regulatesR-26070.699824Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

HINFPup-regulatesR-26260.710238Pr-108
TCF4down-regulatesR-29990.734651Pr-131
ENSG00000054598down-regulatesR-10030.751126Pr-7
ETV5down-regulatesR-341-0.752701Pr-135
ENSG00000245848down-regulatesR-16510.754573Pr-120
SPI1down-regulatesR-2606-0.759833Pr-14
THRAdown-regulatesR-570.789789Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

MAFdown-regulatesR-1080.809932Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

MAFBdown-regulatesR-1730-0.820291Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

XBP1down-regulatesR-3065-0.830078Pr-65
MAFBdown-regulatesR-1741-0.834433Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

MAFBdown-regulatesR-17470.893799Pr-37
MAFGdown-regulatesR-1496-0.904759Pr-101
JUNdown-regulatesR-11810.916484Pr-119

Genes (4)

GPBAR1, RHD, GMFB, C5AR1

Regulons (4)

R-832, R-1181, R-58, R-164

PITX1up-regulatesR-6600.931027Pr-108
HLXdown-regulatesR-27630.933948Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

MAFdown-regulatesR-100-0.952128Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

JUNdown-regulatesR-1184-0.962738Pr-66

Genes (3)

SHISAL2A, USP7, RUNDC1

Regulons (3)

R-2776, R-1184, R-825

ESRRAup-regulatesR-27380.991373Pr-117
GABPAup-regulatesR-1456-1.00351Pr-37
GABPAup-regulatesR-1454-1.00665Pr-135
PBX1down-regulatesR-21121.03594Pr-3
SRFdown-regulatesR-1790-1.04379Pr-27
MAFBdown-regulatesR-1735-1.04652Pr-117
ZNF143up-regulatesR-23141.04902Pr-99
POU2F1down-regulatesR-821.08267Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

FOSdown-regulatesR-2190-1.08799Pr-58
ENSG00000054598down-regulatesR-10081.08851Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

PITX1up-regulatesR-657-1.09874Pr-58
NFE2L2down-regulatesR-1914-1.10423Pr-125
HINFPup-regulatesR-2625-1.11022Pr-118
POU2F1down-regulatesR-67-1.13734Pr-58
CEBPZup-regulatesR-755-1.13966Pr-10
MYCup-regulatesR-20691.14857Pr-117
MAFGdown-regulatesR-1485-1.14909Pr-117
ZNF143up-regulatesR-2323-1.17016Pr-27
ESRRAup-regulatesR-27461.17735Pr-72
THRAdown-regulatesR-581.19237Pr-119

Genes (4)

GPBAR1, RHD, GMFB, C5AR1

Regulons (4)

R-832, R-1181, R-58, R-164

TP53up-regulatesR-3801.1955Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

HMGA1up-regulatesR-836-1.21151Pr-3
SPI1down-regulatesR-2596-1.23045Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

HMGA1up-regulatesR-827-1.23916Pr-3
ENSG00000245848down-regulatesR-16431.28232Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

CREB3L2down-regulatesR-521-1.29128Pr-107

Genes (3)

HIST4H4, BRK1, OCLM

Regulons (4)

R-521, R-2523, R-3056, R-154

RARBup-regulatesR-11061.29549Pr-108
ENSG00000245848down-regulatesR-16461.30305Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

GABPAup-regulatesR-14551.3231Pr-135
ZNF219down-regulatesR-22161.32424Pr-79

Genes (3)

CD2AP, NFAM1, UBE2V1

Regulons (3)

R-2216, R-1862, R-2507

HOXD1down-regulatesR-13031.32893Pr-131
NF1down-regulatesR-125-1.32934Pr-118
SPI1down-regulatesR-26171.33216Pr-135
SPI1down-regulatesR-26081.3599Pr-127
GRHL1up-regulatesR-3145-1.37724Pr-100
POU2F1down-regulatesR-791.37807Pr-131
TP53up-regulatesR-3681.38025Pr-88
BCL6down-regulatesR-536-1.41189Pr-90
POU2F1down-regulatesR-851.43011Pr-127
NR1H3down-regulatesR-65-1.44926Pr-98

Genes (2)

QTRT1

Regulons (3)

R-65, R-1552, R-1565

HMGA1up-regulatesR-825-1.46299Pr-66

Genes (3)

SHISAL2A, USP7, RUNDC1

Regulons (3)

R-2776, R-1184, R-825

TP53up-regulatesR-3661.46351Pr-126
SPI1down-regulatesR-2620-1.46899Pr-88
SRFdown-regulatesR-17841.54282Pr-127
KLF7down-regulatesR-281-1.54497Pr-12
ZBTB3up-regulatesR-12711.5513Pr-117
CEBPZup-regulatesR-757-1.57918Pr-10
ZNF143up-regulatesR-2322-1.59054Pr-3
HMGA1up-regulatesR-8221.59236Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

MAFBdown-regulatesR-17371.60695Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

ETS1down-regulatesR-1-1.61913Pr-64
FOSdown-regulatesR-2192-1.63051Pr-118
MAFGdown-regulatesR-14891.63202Pr-117
ENSG00000123405down-regulatesR-26741.67724Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

USF1down-regulatesR-1859-1.69216Pr-118
SPI1down-regulatesR-26121.70161Pr-126
MAFBdown-regulatesR-1734-1.71974Pr-117
ZBTB4down-regulatesR-20901.72041Pr-117
XBP1down-regulatesR-3055-1.75771Pr-28
MAFBdown-regulatesR-17421.75933Pr-117
CEBPZup-regulatesR-7581.76604Pr-54
RELdown-regulatesR-12761.78446Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

ENSG00000245848down-regulatesR-16391.78812Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

ZFXdown-regulatesR-19301.79489Pr-54
MYCup-regulatesR-20701.79678Pr-117
ZFXdown-regulatesR-1922-1.81972Pr-118
MAFBdown-regulatesR-17321.82103Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

ESRRAup-regulatesR-27361.82545Pr-60
KLF4down-regulatesR-27571.83252Pr-31

Genes (4)

TTC3, ARL4C, GTF2F2, IFRD2

Regulons (4)

R-3135, R-394, R-1836, R-2757

ENSG00000054598down-regulatesR-10111.84026Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

CEBPZup-regulatesR-754-1.9215Pr-89
BCL6down-regulatesR-549-1.94152Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

NRF1down-regulatesR-27041.94607Pr-117
ETS1down-regulatesR-111.98573Pr-138
USF1down-regulatesR-18622.03502Pr-79

Genes (3)

CD2AP, NFAM1, UBE2V1

Regulons (3)

R-2216, R-1862, R-2507

ENSG00000054598down-regulatesR-1007-2.07066Pr-99
E4F1down-regulatesR-3148-2.09252Pr-58
HINFPup-regulatesR-2623-2.10028Pr-110
SPI1down-regulatesR-25982.11907Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

ESRRAup-regulatesR-27392.13083Pr-126
BARX2up-regulatesR-2912.13395Pr-137
CEBPDdown-regulatesR-13072.1379Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

STAT3down-regulatesR-306-2.15021Pr-90
ESRRAup-regulatesR-27442.16113Pr-78

Genes (2)

STIMATE, DDOST

Regulons (6)

R-1941, R-2744, R-656, R-2715, R-2072, R-1512

ENSG00000245848down-regulatesR-16472.18539Pr-126
BCL6down-regulatesR-5422.21429Pr-126
KLF7down-regulatesR-284-2.22134Pr-11
ENSG00000245848down-regulatesR-16482.24486Pr-51

Genes (3)

GPR3

Regulons (8)

R-1926, R-1648, R-3005, R-696, R-2308, R-1210, R-888, R-1531

XBP1down-regulatesR-3058-2.24563Pr-59
ENSG00000123405down-regulatesR-26722.24976Pr-126
NF1down-regulatesR-131-2.28098Pr-118
ESRRAup-regulatesR-27422.37483Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

DBPdown-regulatesR-2957-2.39881Pr-30
SRFdown-regulatesR-17862.43898Pr-117
ENSG00000245848down-regulatesR-1654-2.4448Pr-109
ENSG00000245848down-regulatesR-16522.48648Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

BCL6down-regulatesR-5392.492Pr-117
MYCup-regulatesR-20682.53476Pr-117
ENSG00000245848down-regulatesR-1644-2.57995Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

KLF4down-regulatesR-2755-2.59765Pr-110
ENSG00000245848down-regulatesR-16532.62013Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

ENSG00000165702down-regulatesR-30882.62059Pr-108
TP53up-regulatesR-3612.63177Pr-7
HMGA1up-regulatesR-830-2.65695Pr-109
PPARGdown-regulatesR-2828-2.75451Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

PAX6up-regulatesR-1553-2.79929Pr-110
TFEBdown-regulatesR-887-2.83976Pr-64
ENSG00000105991down-regulatesR-229-2.84707Pr-45

Genes (2)

NDUFA4L2, UCKL1

Regulons (5)

R-2504, R-174, R-25, R-229, R-481

ZNF282up-regulatesR-20142.85693Pr-14
NRF1down-regulatesR-27032.85746Pr-72
SPI1down-regulatesR-2618-2.86595Pr-113
BCL6down-regulatesR-551-2.96315Pr-26

Genes (2)

TEDC1, ZNF688

Regulons (7)

R-3078, R-1915, R-551, R-2188, R-1030, R-512, R-2604

KLF4down-regulatesR-2752-2.99913Pr-36
ETV5down-regulatesR-340-3.04337Pr-36
MYBL2up-regulatesR-6563.10274Pr-78

Genes (2)

STIMATE, DDOST

Regulons (6)

R-1941, R-2744, R-656, R-2715, R-2072, R-1512

MAFBdown-regulatesR-1749-3.13599Pr-110
MAFBdown-regulatesR-1746-3.20928Pr-112
ENSG00000128652down-regulatesR-22593.22334Pr-108
HOXD1down-regulatesR-13013.24332Pr-108
PBX1down-regulatesR-21053.24509Pr-108
IRF8down-regulatesR-26323.31486Pr-108
ZNF219down-regulatesR-22093.35607Pr-108
ENSG00000054598down-regulatesR-10203.39207Pr-72
BCL6down-regulatesR-5543.39207Pr-72
CREB3L2down-regulatesR-522-3.41802Pr-102
ZBTB6up-regulatesR-612-3.42389Pr-61
ZFXdown-regulatesR-19293.48789Pr-117
NF1down-regulatesR-124-3.496Pr-36
STAT3down-regulatesR-3033.51898Pr-108
ZFXdown-regulatesR-1921-3.52781Pr-11
KLF4down-regulatesR-27593.56619Pr-74
RARBup-regulatesR-1108-3.58462Pr-134

Genes (104)

MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1

Regulons (119)

R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272

HLXdown-regulatesR-27613.60545Pr-108
STAT3down-regulatesR-307-3.61941Pr-11
USF1down-regulatesR-1856-3.72712Pr-64
MYCup-regulatesR-20723.75576Pr-78

Genes (2)

STIMATE, DDOST

Regulons (6)

R-1941, R-2744, R-656, R-2715, R-2072, R-1512

ENSG00000245848down-regulatesR-16403.78612Pr-108
MAFBdown-regulatesR-17313.80765Pr-108
LMO2down-regulatesR-909-3.88749Pr-61
KLF7down-regulatesR-2853.90122Pr-74
ETV5down-regulatesR-3433.98861Pr-74
HMGA1up-regulatesR-829-4.15117Pr-3
HINFPup-regulatesR-2622-4.19383Pr-110
SPI1down-regulatesR-26154.23457Pr-74
TCF4down-regulatesR-3001-4.24514Pr-110
ZNF219down-regulatesR-22144.26397Pr-63
HLXdown-regulatesR-2762-4.29241Pr-32
SPI1down-regulatesR-2604-4.30957Pr-26

Genes (2)

TEDC1, ZNF688

Regulons (7)

R-3078, R-1915, R-551, R-2188, R-1030, R-512, R-2604

NR2F6down-regulatesR-1381-4.38369Pr-42
NRF1down-regulatesR-27104.52843Pr-72
MAFdown-regulatesR-105-4.77853Pr-110
MAFdown-regulatesR-1075.09487Pr-114

Genes (3)

PCGF5, SAMD11, KCTD21

Regulons (7)

R-48, R-2383, R-624, R-231, R-1087, R-2653, R-107

SRFdown-regulatesR-1787-5.29074Pr-104
MAFBdown-regulatesR-17435.34371Pr-72
HMGA1up-regulatesR-8316.73331Pr-72
ZNF143up-regulatesR-23197.33249Pr-68
ARID5Bdown-regulatesR-10967.71326Pr-68
E2F2up-regulatesR-29428.59906Pr-68
E2F8up-regulatesR-16268.62493Pr-68
E2F1up-regulatesR-21738.76486Pr-68
E2F1up-regulatesR-21728.82921Pr-68
E2F8up-regulatesR-16279.26408Pr-68

Mutation Causal Mechanistic Flow Network

Cytoscape network of the causal flows influenced by the mutation.

Influences from mutations (magenta chevrons) to regulators (blue triangles) and then from regulators to the given regulon (red square) are indicated with colored edges. Red-colored edges denote up-regulation or activation while green colored edges represent down-regulation or repression.

Mutation Survival Plots

Kaplan-Meier curves demonstrating the sub-stratification of clinical subtypes based upon the network activity of the most predictive individual or pair of genes as determined by the LASSO predictions

no survival information available