Program

Causal Mechanistic Flows with regulons in program Pr-4

MutationRoleRegulatorRoleRegulonHazard Ratio# regulon genesTranscriptional Program
KALRNup-regulatesNFYCrepressesR-2950.1120359Pr-4
MYCdown-regulatesNFYCrepressesR-2950.1120359Pr-4
amp1qdown-regulatesNFYCrepressesR-2950.1120359Pr-4
AHNAK2down-regulatesFOXJ3activatesR-28790.13546232Pr-4
NEBdown-regulatesFOXJ3activatesR-28790.13546232Pr-4
SYNE1down-regulatesFOXJ3activatesR-28790.13546232Pr-4
TACC2down-regulatesFOXJ3activatesR-28790.13546232Pr-4
amp1qup-regulatesFOXJ3activatesR-28790.13546232Pr-4
del13up-regulatesFOXJ3activatesR-28790.13546232Pr-4
FAM46Cdown-regulatesPARP1repressesR-26390.2554419Pr-4
FAT3up-regulatesPARP1repressesR-26390.2554419Pr-4
MACF1up-regulatesPARP1repressesR-26390.2554419Pr-4
MAXup-regulatesPARP1repressesR-26390.2554419Pr-4
FAT3up-regulatesZNF143repressesR-2318-0.278627Pr-4
NRASdown-regulatesZNF143repressesR-2318-0.278627Pr-4
SYNE1up-regulatesZNF143repressesR-2318-0.278627Pr-4
t(14;16)_cytogeneticup-regulatesZNF143repressesR-2318-0.278627Pr-4
AHNAK2down-regulatesTRAF4activatesR-3043-0.3554136Pr-4
DIS3down-regulatesTRAF4activatesR-3043-0.3554136Pr-4
FAT3down-regulatesTRAF4activatesR-3043-0.3554136Pr-4
MACF1down-regulatesTRAF4activatesR-3043-0.3554136Pr-4
MAGI1down-regulatesTRAF4activatesR-3043-0.3554136Pr-4
MAXdown-regulatesTRAF4activatesR-3043-0.3554136Pr-4
MYO10down-regulatesTRAF4activatesR-3043-0.3554136Pr-4
RNASeq_MAFA_Calldown-regulatesTRAF4activatesR-3043-0.3554136Pr-4
DMDdown-regulatesNFE2L2repressesR-19080.42568913Pr-4
ZFHX3up-regulatesNFE2L2repressesR-19080.42568913Pr-4
amp1qdown-regulatesNFE2L2repressesR-19080.42568913Pr-4
del13down-regulatesNFE2L2repressesR-19080.42568913Pr-4
FAT3down-regulatesNFATC2activatesR-1695-0.4543718Pr-4
amp1qup-regulatesNFATC2activatesR-1695-0.4543718Pr-4
del13up-regulatesNFATC2activatesR-1695-0.4543718Pr-4
FGFR3down-regulatesPAX6repressesR-1554-0.53947Pr-4
t(4;14)down-regulatesPAX6repressesR-1554-0.53947Pr-4
amp1qdown-regulatesPAX6repressesR-1554-0.53947Pr-4
del13down-regulatesPAX6repressesR-1554-0.53947Pr-4
AHNAK2down-regulatesZNF281activatesR-2485-0.6417412Pr-4
DMDup-regulatesZNF281activatesR-2485-0.6417412Pr-4
PTPRDdown-regulatesZNF281activatesR-2485-0.6417412Pr-4
RNASeq_MAFB_Calldown-regulatesZNF281activatesR-2485-0.6417412Pr-4
amp1qup-regulatesZNF281activatesR-2485-0.6417412Pr-4
del13up-regulatesZNF281activatesR-2485-0.6417412Pr-4
CYLDdown-regulatesCEBPBrepressesR-1767-0.66120810Pr-4
DCHS1up-regulatesCEBPBrepressesR-1767-0.66120810Pr-4
FAM46Cdown-regulatesCEBPBrepressesR-1767-0.66120810Pr-4
IRF4up-regulatesCEBPBrepressesR-1767-0.66120810Pr-4
MAXup-regulatesCEBPBrepressesR-1767-0.66120810Pr-4
PRKD2up-regulatesCEBPBrepressesR-1767-0.66120810Pr-4
t(11;14)up-regulatesCEBPBrepressesR-1767-0.66120810Pr-4
SETD2up-regulatesCEBPBrepressesR-1767-0.66120810Pr-4
FGFR3up-regulatesCREB5activatesR-777-0.6906477Pr-4
t(4;14)up-regulatesCREB5activatesR-777-0.6906477Pr-4
amp1qup-regulatesCREB5activatesR-777-0.6906477Pr-4
del13up-regulatesCREB5activatesR-777-0.6906477Pr-4
AHNAK2down-regulatesCEBPGactivatesR-443-0.78985211Pr-4
FAT3down-regulatesCEBPGactivatesR-443-0.78985211Pr-4
KALRNdown-regulatesCEBPGactivatesR-443-0.78985211Pr-4
MACF1down-regulatesCEBPGactivatesR-443-0.78985211Pr-4
PTPRDdown-regulatesCEBPGactivatesR-443-0.78985211Pr-4
SYNE1down-regulatesCEBPGactivatesR-443-0.78985211Pr-4
TACC2down-regulatesCEBPGactivatesR-443-0.78985211Pr-4
del13up-regulatesCEBPGactivatesR-443-0.78985211Pr-4
NRASdown-regulatesPEBP1repressesR-17530.9771868Pr-4
RNASeq_FGFR3_Callup-regulatesPEBP1repressesR-17530.9771868Pr-4
t(4;14)up-regulatesPEBP1repressesR-17530.9771868Pr-4
t(14;16)_cytogeneticup-regulatesPEBP1repressesR-17530.9771868Pr-4
t(4;14)_cytogeneticup-regulatesPEBP1repressesR-17530.9771868Pr-4
FGFR3up-regulatesPBX1activatesR-2114-0.9954526Pr-4
PTPRDdown-regulatesPBX1activatesR-2114-0.9954526Pr-4
RNASeq_MAFA_Calldown-regulatesPBX1activatesR-2114-0.9954526Pr-4
t(4;14)up-regulatesPBX1activatesR-2114-0.9954526Pr-4
SDK1down-regulatesPBX1activatesR-2114-0.9954526Pr-4
del13up-regulatesPBX1activatesR-2114-0.9954526Pr-4
AHNAK2down-regulatesNFKB1activatesR-1585-1.049369Pr-4
FAT3down-regulatesNFKB1activatesR-1585-1.049369Pr-4
MAXdown-regulatesNFKB1activatesR-1585-1.049369Pr-4
PTPRDdown-regulatesNFKB1activatesR-1585-1.049369Pr-4
RNASeq_MAFB_Calldown-regulatesNFKB1activatesR-1585-1.049369Pr-4
TACC2down-regulatesNFKB1activatesR-1585-1.049369Pr-4
FAT3down-regulatesNFKB2activatesR-2824-1.722958Pr-4
MAXdown-regulatesNFKB2activatesR-2824-1.722958Pr-4
RNASeq_CCND2_Calldown-regulatesNFKB2activatesR-2824-1.722958Pr-4
RNASeq_FGFR3_Calldown-regulatesNFKB2activatesR-2824-1.722958Pr-4
t(4;14)down-regulatesNFKB2activatesR-2824-1.722958Pr-4
t(4;14)_cytogeneticdown-regulatesNFKB2activatesR-2824-1.722958Pr-4
DNAH5down-regulatesRFX3activatesR-1670-1.812868Pr-4
NEBdown-regulatesRFX3activatesR-1670-1.812868Pr-4
AHNAK2up-regulatesATF1repressesR-560-1.8195323Pr-4
DCHS1up-regulatesATF1repressesR-560-1.8195323Pr-4
DIS3up-regulatesATF1repressesR-560-1.8195323Pr-4
FAM46Cdown-regulatesATF1repressesR-560-1.8195323Pr-4
MACF1up-regulatesATF1repressesR-560-1.8195323Pr-4
MAXup-regulatesATF1repressesR-560-1.8195323Pr-4
PTPRDup-regulatesATF1repressesR-560-1.8195323Pr-4
t(11;14)up-regulatesATF1repressesR-560-1.8195323Pr-4
RNASeq_MAFA_Callup-regulatesATF1repressesR-560-1.8195323Pr-4
RNASeq_MAFB_Callup-regulatesATF1repressesR-560-1.8195323Pr-4
SETD2up-regulatesATF1repressesR-560-1.8195323Pr-4
t(14;16)_cytogeneticup-regulatesATF1repressesR-560-1.8195323Pr-4
DCHS1up-regulatesNFYCrepressesR-293-1.9083216Pr-4
FAM46Cdown-regulatesNFYCrepressesR-293-1.9083216Pr-4
KALRNup-regulatesNFYCrepressesR-293-1.9083216Pr-4
NRASdown-regulatesNFYCrepressesR-293-1.9083216Pr-4
RNASeq_FGFR3_Callup-regulatesNFYCrepressesR-293-1.9083216Pr-4
RNASeq_MAFA_Callup-regulatesNFYCrepressesR-293-1.9083216Pr-4
RNASeq_MAFB_Callup-regulatesNFYCrepressesR-293-1.9083216Pr-4
t(4;14)up-regulatesNFYCrepressesR-293-1.9083216Pr-4
t(4;14)_cytogeneticup-regulatesNFYCrepressesR-293-1.9083216Pr-4
BAI3down-regulatesCREB5activatesR-773-2.0087915Pr-4
MYO10down-regulatesCREB5activatesR-773-2.0087915Pr-4
SVILdown-regulatesCREB5activatesR-773-2.0087915Pr-4
del13up-regulatesCREB5activatesR-773-2.0087915Pr-4
t(14;16)_cytogeneticdown-regulatesCREB5activatesR-773-2.0087915Pr-4
AHNAK2down-regulatesEP300activatesR-2432-2.0646212Pr-4
MAGI1down-regulatesEP300activatesR-2432-2.0646212Pr-4
TACC2down-regulatesEP300activatesR-2432-2.0646212Pr-4
del13up-regulatesEP300activatesR-2432-2.0646212Pr-4
AHNAK2down-regulatesCREB1activatesR-270-2.1391519Pr-4
FAT3down-regulatesCREB1activatesR-270-2.1391519Pr-4
MAXdown-regulatesCREB1activatesR-270-2.1391519Pr-4
del13up-regulatesCREB1activatesR-270-2.1391519Pr-4
AHNAK2up-regulatesVBP1repressesR-2099-2.1671521Pr-4
DCHS1up-regulatesVBP1repressesR-2099-2.1671521Pr-4
FAT3up-regulatesVBP1repressesR-2099-2.1671521Pr-4
MACF1up-regulatesVBP1repressesR-2099-2.1671521Pr-4
PTPRDup-regulatesVBP1repressesR-2099-2.1671521Pr-4
RNASeq_MAFA_Callup-regulatesVBP1repressesR-2099-2.1671521Pr-4
SYNE1up-regulatesVBP1repressesR-2099-2.1671521Pr-4
TACC2up-regulatesVBP1repressesR-2099-2.1671521Pr-4
del13down-regulatesVBP1repressesR-2099-2.1671521Pr-4
t(14;16)_cytogeneticup-regulatesVBP1repressesR-2099-2.1671521Pr-4
FGFR3up-regulatesCREB5activatesR-7782.183656Pr-4
SVILdown-regulatesCREB5activatesR-7782.183656Pr-4
AHNAK2down-regulatesSRFactivatesR-1778-2.2654991Pr-4
DIS3down-regulatesSRFactivatesR-1778-2.2654991Pr-4
FAM46Cup-regulatesSRFactivatesR-1778-2.2654991Pr-4
FAT3down-regulatesSRFactivatesR-1778-2.2654991Pr-4
MACF1down-regulatesSRFactivatesR-1778-2.2654991Pr-4
t(11;14)down-regulatesSRFactivatesR-1778-2.2654991Pr-4
RNASeq_FGFR3_Calldown-regulatesSRFactivatesR-1778-2.2654991Pr-4
RNASeq_MAFA_Calldown-regulatesSRFactivatesR-1778-2.2654991Pr-4
RNASeq_MAFB_Calldown-regulatesSRFactivatesR-1778-2.2654991Pr-4
t(4;14)down-regulatesSRFactivatesR-1778-2.2654991Pr-4
SETD2down-regulatesSRFactivatesR-1778-2.2654991Pr-4
SYNE1down-regulatesSRFactivatesR-1778-2.2654991Pr-4
TACC2down-regulatesSRFactivatesR-1778-2.2654991Pr-4
MAGI1down-regulatesCDC5LactivatesR-1633-2.283786Pr-4
TACC2down-regulatesCDC5LactivatesR-1633-2.283786Pr-4
del13up-regulatesCDC5LactivatesR-1633-2.283786Pr-4
NEBdown-regulatesRELactivatesR-1277-2.2901614Pr-4
TACC2down-regulatesRELactivatesR-1277-2.2901614Pr-4
AHNAK2down-regulatesRELAactivatesR-1463-2.3039915Pr-4
DCHS1down-regulatesRELAactivatesR-1463-2.3039915Pr-4
FAT3down-regulatesRELAactivatesR-1463-2.3039915Pr-4
MACF1down-regulatesRELAactivatesR-1463-2.3039915Pr-4
MYO10down-regulatesRELAactivatesR-1463-2.3039915Pr-4
NEBdown-regulatesRELAactivatesR-1463-2.3039915Pr-4
PCDH10down-regulatesRELAactivatesR-1463-2.3039915Pr-4
PTPRDdown-regulatesRELAactivatesR-1463-2.3039915Pr-4
RNASeq_MAFA_Calldown-regulatesRELAactivatesR-1463-2.3039915Pr-4
SYNE1down-regulatesRELAactivatesR-1463-2.3039915Pr-4
TACC2down-regulatesRELAactivatesR-1463-2.3039915Pr-4
del13up-regulatesRELAactivatesR-1463-2.3039915Pr-4
DIS3down-regulatesHMGA1activatesR-818-2.3158858Pr-4
FAM46Cup-regulatesHMGA1activatesR-818-2.3158858Pr-4
MAXdown-regulatesHMGA1activatesR-818-2.3158858Pr-4
NRASup-regulatesHMGA1activatesR-818-2.3158858Pr-4
RNASeq_FGFR3_Calldown-regulatesHMGA1activatesR-818-2.3158858Pr-4
RNASeq_MAFA_Calldown-regulatesHMGA1activatesR-818-2.3158858Pr-4
RNASeq_MAFB_Calldown-regulatesHMGA1activatesR-818-2.3158858Pr-4
t(4;14)down-regulatesHMGA1activatesR-818-2.3158858Pr-4
t(4;14)_cytogeneticdown-regulatesHMGA1activatesR-818-2.3158858Pr-4
AHNAK2down-regulatesIRF1activatesR-176-2.3375575Pr-4
NRASup-regulatesIRF1activatesR-176-2.3375575Pr-4
AHNAK2down-regulatesNFKB1activatesR-1573-2.3535239Pr-4
DCHS1down-regulatesNFKB1activatesR-1573-2.3535239Pr-4
DIS3down-regulatesNFKB1activatesR-1573-2.3535239Pr-4
FAM46Cup-regulatesNFKB1activatesR-1573-2.3535239Pr-4
FAT3down-regulatesNFKB1activatesR-1573-2.3535239Pr-4
MACF1down-regulatesNFKB1activatesR-1573-2.3535239Pr-4
MAXdown-regulatesNFKB1activatesR-1573-2.3535239Pr-4
MYO10down-regulatesNFKB1activatesR-1573-2.3535239Pr-4
PTPRDdown-regulatesNFKB1activatesR-1573-2.3535239Pr-4
RNASeq_CCND2_Calldown-regulatesNFKB1activatesR-1573-2.3535239Pr-4
RNASeq_FGFR3_Calldown-regulatesNFKB1activatesR-1573-2.3535239Pr-4
RNASeq_MAFB_Calldown-regulatesNFKB1activatesR-1573-2.3535239Pr-4
t(4;14)down-regulatesNFKB1activatesR-1573-2.3535239Pr-4
TACC2down-regulatesNFKB1activatesR-1573-2.3535239Pr-4
t(4;14)_cytogeneticdown-regulatesNFKB1activatesR-1573-2.3535239Pr-4
DIS3up-regulatesNFYArepressesR-1468-2.3758638Pr-4
NRASdown-regulatesNFYArepressesR-1468-2.3758638Pr-4
t(11;14)up-regulatesNFYArepressesR-1468-2.3758638Pr-4
RNASeq_FGFR3_Callup-regulatesNFYArepressesR-1468-2.3758638Pr-4
t(4;14)up-regulatesNFYArepressesR-1468-2.3758638Pr-4
t(4;14)_cytogeneticup-regulatesNFYArepressesR-1468-2.3758638Pr-4
MAGI1down-regulatesSPI1activatesR-2599-2.3939183Pr-4
PTPRDdown-regulatesSPI1activatesR-2599-2.3939183Pr-4
RNASeq_FGFR3_Calldown-regulatesSPI1activatesR-2599-2.3939183Pr-4
t(4;14)down-regulatesSPI1activatesR-2599-2.3939183Pr-4
SYNE1down-regulatesSPI1activatesR-2599-2.3939183Pr-4
t(14;16)_cytogeneticdown-regulatesSPI1activatesR-2599-2.3939183Pr-4
AHNAK2down-regulatesMAFKactivatesR-2799-2.4125859Pr-4
ASXL3down-regulatesMAFKactivatesR-2799-2.4125859Pr-4
DCHS1down-regulatesMAFKactivatesR-2799-2.4125859Pr-4
FAT3down-regulatesMAFKactivatesR-2799-2.4125859Pr-4
KALRNdown-regulatesMAFKactivatesR-2799-2.4125859Pr-4
MACF1down-regulatesMAFKactivatesR-2799-2.4125859Pr-4
MAGI1down-regulatesMAFKactivatesR-2799-2.4125859Pr-4
MYO10down-regulatesMAFKactivatesR-2799-2.4125859Pr-4
NEBdown-regulatesMAFKactivatesR-2799-2.4125859Pr-4
PTPRDdown-regulatesMAFKactivatesR-2799-2.4125859Pr-4
RNASeq_MAFA_Calldown-regulatesMAFKactivatesR-2799-2.4125859Pr-4
SYNE1down-regulatesMAFKactivatesR-2799-2.4125859Pr-4
TACC2down-regulatesMAFKactivatesR-2799-2.4125859Pr-4
del13up-regulatesMAFKactivatesR-2799-2.4125859Pr-4
AHNAK2down-regulatesPOU2F1activatesR-68-2.4258993Pr-4
FAT3down-regulatesPOU2F1activatesR-68-2.4258993Pr-4
KALRNdown-regulatesPOU2F1activatesR-68-2.4258993Pr-4
MACF1down-regulatesPOU2F1activatesR-68-2.4258993Pr-4
MAGI1down-regulatesPOU2F1activatesR-68-2.4258993Pr-4
MYO10down-regulatesPOU2F1activatesR-68-2.4258993Pr-4
NEBdown-regulatesPOU2F1activatesR-68-2.4258993Pr-4
PTPRDdown-regulatesPOU2F1activatesR-68-2.4258993Pr-4
TACC2down-regulatesPOU2F1activatesR-68-2.4258993Pr-4
amp1qup-regulatesPOU2F1activatesR-68-2.4258993Pr-4
del13up-regulatesPOU2F1activatesR-68-2.4258993Pr-4
RNASeq_FGFR3_Callup-regulatesDBPrepressesR-2950-2.433226Pr-4
t(4;14)up-regulatesDBPrepressesR-2950-2.433226Pr-4
amp1qdown-regulatesDBPrepressesR-2950-2.433226Pr-4
DIS3down-regulatesFOXO3activatesR-2767-2.5165876Pr-4
FAM46Cup-regulatesFOXO3activatesR-2767-2.5165876Pr-4
NRASup-regulatesFOXO3activatesR-2767-2.5165876Pr-4
t(11;14)down-regulatesFOXO3activatesR-2767-2.5165876Pr-4
RNASeq_MAFA_Calldown-regulatesFOXO3activatesR-2767-2.5165876Pr-4
SETD2down-regulatesFOXO3activatesR-2767-2.5165876Pr-4
t(11;14)_cytogeneticdown-regulatesFOXO3activatesR-2767-2.5165876Pr-4
t(4;14)_cytogeneticdown-regulatesFOXO3activatesR-2767-2.5165876Pr-4
DIS3up-regulatesJUNrepressesR-1174-2.5525464Pr-4
t(11;14)up-regulatesJUNrepressesR-1174-2.5525464Pr-4
AHNAK2down-regulatesIKZF1activatesR-990-2.5562314Pr-4
DNAH5down-regulatesIKZF1activatesR-990-2.5562314Pr-4
KALRNdown-regulatesIKZF1activatesR-990-2.5562314Pr-4
MACF1down-regulatesIKZF1activatesR-990-2.5562314Pr-4
t(11;14)up-regulatesIKZF1activatesR-990-2.5562314Pr-4
t(11;14)_cytogeneticup-regulatesIKZF1activatesR-990-2.5562314Pr-4
AHNAK2down-regulatesSTAT4activatesR-2658-2.583466Pr-4
MAXdown-regulatesIRX3activatesR-2221-2.6840533Pr-4
RNASeq_MAFA_Calldown-regulatesIRX3activatesR-2221-2.6840533Pr-4
SYNE1down-regulatesIRX3activatesR-2221-2.6840533Pr-4
t(14;16)_cytogeneticdown-regulatesIRX3activatesR-2221-2.6840533Pr-4
AHNAK2down-regulatesZNF281activatesR-2487-2.704669Pr-4
CMYA5down-regulatesZNF281activatesR-2487-2.704669Pr-4
FAT3down-regulatesZNF281activatesR-2487-2.704669Pr-4
MACF1down-regulatesZNF281activatesR-2487-2.704669Pr-4
NEBdown-regulatesZNF281activatesR-2487-2.704669Pr-4
PTPRDdown-regulatesZNF281activatesR-2487-2.704669Pr-4
t(11;14)up-regulatesZNF281activatesR-2487-2.704669Pr-4
RNASeq_MAFB_Calldown-regulatesZNF281activatesR-2487-2.704669Pr-4
SYNE1down-regulatesZNF281activatesR-2487-2.704669Pr-4
TACC2down-regulatesZNF281activatesR-2487-2.704669Pr-4
del13up-regulatesZNF281activatesR-2487-2.704669Pr-4
AHNAK2down-regulatesNFIL3activatesR-1684-2.8207923Pr-4
DCHS1down-regulatesNFIL3activatesR-1684-2.8207923Pr-4
FAT3down-regulatesNFIL3activatesR-1684-2.8207923Pr-4
MAGI1down-regulatesNFIL3activatesR-1684-2.8207923Pr-4
MAXdown-regulatesNFIL3activatesR-1684-2.8207923Pr-4
RNASeq_FGFR3_Calldown-regulatesNFIL3activatesR-1684-2.8207923Pr-4
RNASeq_MAFA_Calldown-regulatesNFIL3activatesR-1684-2.8207923Pr-4
t(4;14)down-regulatesNFIL3activatesR-1684-2.8207923Pr-4
SETD2down-regulatesNFIL3activatesR-1684-2.8207923Pr-4
SYNE1down-regulatesNFIL3activatesR-1684-2.8207923Pr-4
TACC2down-regulatesNFIL3activatesR-1684-2.8207923Pr-4
FAT3up-regulatesXBP1repressesR-3051-2.8510722Pr-4
MAXup-regulatesXBP1repressesR-3051-2.8510722Pr-4
t(4;14)up-regulatesXBP1repressesR-3051-2.8510722Pr-4
t(14;16)_cytogeneticup-regulatesXBP1repressesR-3051-2.8510722Pr-4
AHNAK2down-regulatesMAFKactivatesR-2813-3.128748Pr-4
DCHS1down-regulatesMAFKactivatesR-2813-3.128748Pr-4
DNAH5down-regulatesMAFKactivatesR-2813-3.128748Pr-4
FAT3down-regulatesMAFKactivatesR-2813-3.128748Pr-4
MYO10down-regulatesMAFKactivatesR-2813-3.128748Pr-4
NEBdown-regulatesMAFKactivatesR-2813-3.128748Pr-4
PTPRDdown-regulatesMAFKactivatesR-2813-3.128748Pr-4
RNASeq_MAFA_Calldown-regulatesMAFKactivatesR-2813-3.128748Pr-4
SYNE1down-regulatesMAFKactivatesR-2813-3.128748Pr-4
TACC2down-regulatesMAFKactivatesR-2813-3.128748Pr-4
DCHS1down-regulatesENSG00000054598activatesR-1017-3.36259Pr-4
NEBdown-regulatesENSG00000054598activatesR-1017-3.36259Pr-4
PTPRDdown-regulatesENSG00000054598activatesR-1017-3.36259Pr-4
t(11;14)up-regulatesENSG00000054598activatesR-1017-3.36259Pr-4
TRAF3down-regulatesENSG00000054598activatesR-1017-3.36259Pr-4
del17down-regulatesENSG00000054598activatesR-1017-3.36259Pr-4
t(14;16)_cytogeneticdown-regulatesENSG00000054598activatesR-1017-3.36259Pr-4
AHNAK2up-regulatesMAZrepressesR-506-4.853539Pr-4
DCHS1up-regulatesMAZrepressesR-506-4.853539Pr-4
DIS3up-regulatesMAZrepressesR-506-4.853539Pr-4
DNAH10up-regulatesMAZrepressesR-506-4.853539Pr-4
FAM46Cdown-regulatesMAZrepressesR-506-4.853539Pr-4
FAT3up-regulatesMAZrepressesR-506-4.853539Pr-4
FGFR3up-regulatesMAZrepressesR-506-4.853539Pr-4
MACF1up-regulatesMAZrepressesR-506-4.853539Pr-4
NRASdown-regulatesMAZrepressesR-506-4.853539Pr-4
PRKD2up-regulatesMAZrepressesR-506-4.853539Pr-4
RELNup-regulatesMAZrepressesR-506-4.853539Pr-4
RNASeq_FGFR3_Callup-regulatesMAZrepressesR-506-4.853539Pr-4
RNASeq_MAFA_Callup-regulatesMAZrepressesR-506-4.853539Pr-4
RNASeq_MAFB_Callup-regulatesMAZrepressesR-506-4.853539Pr-4
t(14;16)up-regulatesMAZrepressesR-506-4.853539Pr-4
t(4;14)up-regulatesMAZrepressesR-506-4.853539Pr-4
SETD2up-regulatesMAZrepressesR-506-4.853539Pr-4
TP53up-regulatesMAZrepressesR-506-4.853539Pr-4
t(14;16)_cytogeneticup-regulatesMAZrepressesR-506-4.853539Pr-4
t(4;14)_cytogeneticup-regulatesMAZrepressesR-506-4.853539Pr-4

Regulons in program Pr-4

Regulon Cox Hazard Ratio # genes # causal flows
R-2950.11203593
R-28790.135462326
R-26390.25544194
R-2318-0.2786274
R-3043-0.35541368
R-19080.425689134
R-1695-0.45437183
R-1554-0.539474
R-2485-0.64174126
R-1767-0.661208108
R-777-0.69064774
R-443-0.789852118
R-17530.97718685
R-2114-0.99545266
R-1585-1.0493696
R-2824-1.7229586
R-1670-1.8128682
R-560-1.819532312
R-293-1.90832169
R-773-2.00879155
R-2432-2.06462124
R-270-2.13915194
R-2099-2.167152110
R-7782.1836562
R-1778-2.265499113
R-1633-2.2837863
R-1277-2.29016142
R-1463-2.303991512
R-818-2.31588589
R-176-2.33755752
R-1573-2.353523915
R-1468-2.37586386
R-2599-2.39391836
R-2799-2.412585914
R-68-2.425899311
R-2950-2.4332263
R-2767-2.51658768
R-1174-2.55254642
R-990-2.55623146
R-2658-2.5834661
R-2221-2.68405334
R-2487-2.70466911
R-1684-2.820792311
R-3051-2.85107224
R-2813-3.12874810
R-1017-3.362597
R-506-4.85353920

Program Survival Plots

Kaplan-Meier curves demonstrating the sub-stratification of clinical subtypes based upon the network activity of the most predictive individual or pair of genes as determined by the LASSO predictions