Program

Causal Mechanistic Flows with regulons in program Pr-2

MutationRoleRegulatorRoleRegulonHazard Ratio# regulon genesTranscriptional Program
del13up-regulatesUSF1activatesR-1855-0.057076111Pr-2
t(11;14)_cytogeneticup-regulatesUSF1activatesR-1855-0.057076111Pr-2
AHNAK2down-regulatesRORAactivatesR-2267-0.065542416Pr-2
BRAFup-regulatesRORAactivatesR-2267-0.065542416Pr-2
del13up-regulatesRORAactivatesR-2267-0.065542416Pr-2
AHNAK2down-regulatesTRAF4activatesR-3037-0.069899716Pr-2
CMYA5down-regulatesTRAF4activatesR-3037-0.069899716Pr-2
FAT3down-regulatesTRAF4activatesR-3037-0.069899716Pr-2
MACF1down-regulatesTRAF4activatesR-3037-0.069899716Pr-2
NEBdown-regulatesTRAF4activatesR-3037-0.069899716Pr-2
PCDH10down-regulatesTRAF4activatesR-3037-0.069899716Pr-2
PTPRDdown-regulatesTRAF4activatesR-3037-0.069899716Pr-2
t(11;14)up-regulatesTRAF4activatesR-3037-0.069899716Pr-2
RNASeq_MAFB_Calldown-regulatesTRAF4activatesR-3037-0.069899716Pr-2
TACC2down-regulatesTRAF4activatesR-3037-0.069899716Pr-2
AHNAK2down-regulatesDDIT3activatesR-486-0.07965637Pr-2
CMYA5down-regulatesDDIT3activatesR-486-0.07965637Pr-2
MYO10down-regulatesDDIT3activatesR-486-0.07965637Pr-2
NEBdown-regulatesDDIT3activatesR-486-0.07965637Pr-2
t(11;14)up-regulatesDDIT3activatesR-486-0.07965637Pr-2
amp1qup-regulatesDDIT3activatesR-486-0.07965637Pr-2
del13up-regulatesDDIT3activatesR-486-0.07965637Pr-2
t(11;14)_cytogeneticup-regulatesDDIT3activatesR-486-0.07965637Pr-2
AHNAK2up-regulatesSP1repressesR-2717-0.094882432Pr-2
PTPRDup-regulatesSP1repressesR-2717-0.094882432Pr-2
RNASeq_MAFA_Callup-regulatesSP1repressesR-2717-0.094882432Pr-2
RNASeq_MAFB_Callup-regulatesSP1repressesR-2717-0.094882432Pr-2
amp1qup-regulatesMEF2DactivatesR-8780.1017346Pr-2
del13up-regulatesMEF2DactivatesR-8780.1017346Pr-2
t(11;14)down-regulatesTP53repressesR-3630.10382916Pr-2
RNASeq_FGFR3_Calldown-regulatesTP53repressesR-3630.10382916Pr-2
t(4;14)down-regulatesTP53repressesR-3630.10382916Pr-2
SYNE1up-regulatesTP53repressesR-3630.10382916Pr-2
amp1qdown-regulatesTP53repressesR-3630.10382916Pr-2
del13down-regulatesTP53repressesR-3630.10382916Pr-2
AHNAK2up-regulatesVBP1repressesR-2104-0.1541866Pr-2
CMYA5up-regulatesVBP1repressesR-2104-0.1541866Pr-2
MACF1up-regulatesVBP1repressesR-2104-0.1541866Pr-2
MYO10up-regulatesVBP1repressesR-2104-0.1541866Pr-2
NEBup-regulatesVBP1repressesR-2104-0.1541866Pr-2
PTPRDup-regulatesVBP1repressesR-2104-0.1541866Pr-2
RNASeq_MAFA_Callup-regulatesVBP1repressesR-2104-0.1541866Pr-2
SYNE1up-regulatesVBP1repressesR-2104-0.1541866Pr-2
TACC2up-regulatesVBP1repressesR-2104-0.1541866Pr-2
del13down-regulatesVBP1repressesR-2104-0.1541866Pr-2
del17up-regulatesVBP1repressesR-2104-0.1541866Pr-2
del17pup-regulatesVBP1repressesR-2104-0.1541866Pr-2
t(14;16)_cytogeneticup-regulatesVBP1repressesR-2104-0.1541866Pr-2
AHNAK2up-regulatesZSCAN16repressesR-631-0.1655966Pr-2
CMYA5up-regulatesZSCAN16repressesR-631-0.1655966Pr-2
FAT3up-regulatesZSCAN16repressesR-631-0.1655966Pr-2
MACF1up-regulatesZSCAN16repressesR-631-0.1655966Pr-2
NEBup-regulatesZSCAN16repressesR-631-0.1655966Pr-2
PCDH10up-regulatesZSCAN16repressesR-631-0.1655966Pr-2
PTPRDup-regulatesZSCAN16repressesR-631-0.1655966Pr-2
t(11;14)down-regulatesZSCAN16repressesR-631-0.1655966Pr-2
t(4;14)down-regulatesZSCAN16repressesR-631-0.1655966Pr-2
SYNE1up-regulatesZSCAN16repressesR-631-0.1655966Pr-2
del13down-regulatesZSCAN16repressesR-631-0.1655966Pr-2
AHNAK2down-regulatesNR3C1activatesR-3178-0.17304624Pr-2
PCDH10down-regulatesNR3C1activatesR-3178-0.17304624Pr-2
t(14;16)up-regulatesNR3C1activatesR-3178-0.17304624Pr-2
del13up-regulatesNR3C1activatesR-3178-0.17304624Pr-2
AHNAK2up-regulatesATF1repressesR-5630.21933513Pr-2
PCDH10up-regulatesATF1repressesR-5630.21933513Pr-2
FAT3up-regulatesNFE2L2repressesR-1911-0.24623912Pr-2
MACF1up-regulatesNFE2L2repressesR-1911-0.24623912Pr-2
amp1qdown-regulatesNFE2L2repressesR-1911-0.24623912Pr-2
del13down-regulatesNFE2L2repressesR-1911-0.24623912Pr-2
AHNAK2down-regulatesCEBPGactivatesR-436-0.25864519Pr-2
FAT3down-regulatesCEBPGactivatesR-436-0.25864519Pr-2
MACF1down-regulatesCEBPGactivatesR-436-0.25864519Pr-2
MYO10down-regulatesCEBPGactivatesR-436-0.25864519Pr-2
NEBdown-regulatesCEBPGactivatesR-436-0.25864519Pr-2
PCDH10down-regulatesCEBPGactivatesR-436-0.25864519Pr-2
PTPRDdown-regulatesCEBPGactivatesR-436-0.25864519Pr-2
RNASeq_MAFA_Calldown-regulatesCEBPGactivatesR-436-0.25864519Pr-2
SYNE1down-regulatesCEBPGactivatesR-436-0.25864519Pr-2
TACC2down-regulatesCEBPGactivatesR-436-0.25864519Pr-2
amp1qup-regulatesCEBPGactivatesR-436-0.25864519Pr-2
del13up-regulatesCEBPGactivatesR-436-0.25864519Pr-2
AHNAK2down-regulatesIRF1activatesR-183-0.26189329Pr-2
t(11;14)up-regulatesIRF1activatesR-183-0.26189329Pr-2
t(14;16)up-regulatesIRF1activatesR-183-0.26189329Pr-2
t(11;14)_cytogeneticup-regulatesIRF1activatesR-183-0.26189329Pr-2
AHNAK2down-regulatesELF1activatesR-2977-0.27217321Pr-2
PCDH10down-regulatesELF1activatesR-2977-0.27217321Pr-2
t(11;14)up-regulatesELF1activatesR-2977-0.27217321Pr-2
t(11;14)_cytogeneticup-regulatesELF1activatesR-2977-0.27217321Pr-2
AHNAK2down-regulatesPOU2F1activatesR-78-0.27241833Pr-2
CMYA5down-regulatesPOU2F1activatesR-78-0.27241833Pr-2
FAT3down-regulatesPOU2F1activatesR-78-0.27241833Pr-2
MACF1down-regulatesPOU2F1activatesR-78-0.27241833Pr-2
NEBdown-regulatesPOU2F1activatesR-78-0.27241833Pr-2
PTPRDdown-regulatesPOU2F1activatesR-78-0.27241833Pr-2
t(11;14)up-regulatesPOU2F1activatesR-78-0.27241833Pr-2
TACC2down-regulatesPOU2F1activatesR-78-0.27241833Pr-2
amp1qup-regulatesPOU2F1activatesR-78-0.27241833Pr-2
del13up-regulatesPOU2F1activatesR-78-0.27241833Pr-2
t(11;14)_cytogeneticup-regulatesPOU2F1activatesR-78-0.27241833Pr-2
AHNAK2down-regulatesZNF281activatesR-2479-0.33336823Pr-2
CMYA5down-regulatesZNF281activatesR-2479-0.33336823Pr-2
MACF1down-regulatesZNF281activatesR-2479-0.33336823Pr-2
NEBdown-regulatesZNF281activatesR-2479-0.33336823Pr-2
PCDH10down-regulatesZNF281activatesR-2479-0.33336823Pr-2
PTPRDdown-regulatesZNF281activatesR-2479-0.33336823Pr-2
t(11;14)up-regulatesZNF281activatesR-2479-0.33336823Pr-2
RNASeq_MAFB_Calldown-regulatesZNF281activatesR-2479-0.33336823Pr-2
t(4;14)up-regulatesZNF281activatesR-2479-0.33336823Pr-2
SYNE1down-regulatesZNF281activatesR-2479-0.33336823Pr-2
TACC2down-regulatesZNF281activatesR-2479-0.33336823Pr-2
del13up-regulatesZNF281activatesR-2479-0.33336823Pr-2
t(11;14)_cytogeneticup-regulatesZNF281activatesR-2479-0.33336823Pr-2
AHNAK2down-regulatesATF3activatesR-24110.3395297Pr-2
CMYA5down-regulatesATF3activatesR-24110.3395297Pr-2
RNASeq_FGFR3_Callup-regulatesATF3activatesR-24110.3395297Pr-2
RNASeq_MAFB_Calldown-regulatesATF3activatesR-24110.3395297Pr-2
t(4;14)up-regulatesATF3activatesR-24110.3395297Pr-2
SYNE1down-regulatesATF3activatesR-24110.3395297Pr-2
RNASeq_MAFB_Callup-regulatesNFE2L1repressesR-1825-0.3436098Pr-2
AHNAK2down-regulatesHSF1activatesR-49-0.35025215Pr-2
FAT3down-regulatesHSF1activatesR-49-0.35025215Pr-2
MACF1down-regulatesHSF1activatesR-49-0.35025215Pr-2
NEBdown-regulatesHSF1activatesR-49-0.35025215Pr-2
RNASeq_MAFB_Calldown-regulatesHSF1activatesR-49-0.35025215Pr-2
SYNE1down-regulatesHSF1activatesR-49-0.35025215Pr-2
TACC2down-regulatesHSF1activatesR-49-0.35025215Pr-2
del13up-regulatesHSF1activatesR-49-0.35025215Pr-2
AHNAK2down-regulatesCREB1activatesR-2720.36697411Pr-2
CMYA5down-regulatesCREB1activatesR-2720.36697411Pr-2
t(14;16)up-regulatesCREB1activatesR-2720.36697411Pr-2
amp1qup-regulatesCREB1activatesR-2720.36697411Pr-2
del13up-regulatesCREB1activatesR-2720.36697411Pr-2
SP140down-regulatesZNF740repressesR-390-0.3748817Pr-2
amp1qdown-regulatesZNF740repressesR-390-0.3748817Pr-2
del13down-regulatesZNF740repressesR-390-0.3748817Pr-2
AHNAK2down-regulatesMEF2AactivatesR-1869-0.39702233Pr-2
FAT3down-regulatesMEF2AactivatesR-1869-0.39702233Pr-2
MACF1down-regulatesMEF2AactivatesR-1869-0.39702233Pr-2
MYO10down-regulatesMEF2AactivatesR-1869-0.39702233Pr-2
RNASeq_MAFB_Calldown-regulatesMEF2AactivatesR-1869-0.39702233Pr-2
SYNE1down-regulatesMEF2AactivatesR-1869-0.39702233Pr-2
TACC2down-regulatesMEF2AactivatesR-1869-0.39702233Pr-2
amp1qup-regulatesMEF2AactivatesR-1869-0.39702233Pr-2
del13up-regulatesMEF2AactivatesR-1869-0.39702233Pr-2
AHNAK2down-regulatesHBP1activatesR-1831-0.39754519Pr-2
MACF1down-regulatesHBP1activatesR-1831-0.39754519Pr-2
NEBdown-regulatesHBP1activatesR-1831-0.39754519Pr-2
PCDH10down-regulatesHBP1activatesR-1831-0.39754519Pr-2
t(11;14)up-regulatesHBP1activatesR-1831-0.39754519Pr-2
SYNE1down-regulatesHBP1activatesR-1831-0.39754519Pr-2
TACC2down-regulatesHBP1activatesR-1831-0.39754519Pr-2
amp1qup-regulatesHBP1activatesR-1831-0.39754519Pr-2
del13up-regulatesHBP1activatesR-1831-0.39754519Pr-2
NEBdown-regulatesIRX3activatesR-2225-0.39904413Pr-2
SYNE1down-regulatesIRX3activatesR-2225-0.39904413Pr-2
FAT3down-regulatesNFKB1activatesR-15860.401558Pr-2
SVILdown-regulatesNFKB1activatesR-15860.401558Pr-2
ZFHX3down-regulatesNFKB1activatesR-15860.401558Pr-2
RNASeq_FGFR3_Callup-regulatesCREB5activatesR-7750.44692412Pr-2
t(4;14)up-regulatesCREB5activatesR-7750.44692412Pr-2
amp1qup-regulatesCREB5activatesR-7750.44692412Pr-2
del13up-regulatesCREB5activatesR-7750.44692412Pr-2
t(4;14)_cytogeneticup-regulatesCREB5activatesR-7750.44692412Pr-2
NEBdown-regulatesBCL6activatesR-535-0.47832131Pr-2
t(11;14)up-regulatesBCL6activatesR-535-0.47832131Pr-2
SYNE1down-regulatesBCL6activatesR-535-0.47832131Pr-2
AHNAK2down-regulatesRFX3activatesR-1660-0.49581613Pr-2
CMYA5down-regulatesRFX3activatesR-1660-0.49581613Pr-2
MYO10down-regulatesRFX3activatesR-1660-0.49581613Pr-2
NEBdown-regulatesRFX3activatesR-1660-0.49581613Pr-2

Genes (47)

MSRA, PLEKHF2, NUPR1<