Program

Causal Mechanistic Flows with regulons in program Pr-9

MutationRoleRegulatorRoleRegulonHazard Ratio# regulon genesTranscriptional Program
AHNAK2down-regulatesBBXactivatesR-1534-0.4824769Pr-9
CYLDup-regulatesBBXactivatesR-1534-0.4824769Pr-9
FAT3down-regulatesBBXactivatesR-1534-0.4824769Pr-9
MAXdown-regulatesBBXactivatesR-1534-0.4824769Pr-9
RNASeq_CCND2_Calldown-regulatesBBXactivatesR-1534-0.4824769Pr-9
PRKD2up-regulatesRELactivatesR-12780.5024168Pr-9
t(11;14)up-regulatesRELactivatesR-12780.5024168Pr-9
RNASeq_FGFR3_Callup-regulatesRELactivatesR-12780.5024168Pr-9
del1pup-regulatesRELactivatesR-12780.5024168Pr-9
t(11;14)_cytogeneticup-regulatesRELactivatesR-12780.5024168Pr-9
t(14;16)_cytogeneticdown-regulatesRELactivatesR-12780.5024168Pr-9
AHNAK2down-regulatesRREB1activatesR-2296-0.75723212Pr-9
CMYA5down-regulatesRREB1activatesR-2296-0.75723212Pr-9
FAT3down-regulatesRREB1activatesR-2296-0.75723212Pr-9
KDM3Bdown-regulatesRREB1activatesR-2296-0.75723212Pr-9
MACF1down-regulatesRREB1activatesR-2296-0.75723212Pr-9
RNASeq_FGFR3_Calldown-regulatesRREB1activatesR-2296-0.75723212Pr-9
RNASeq_MAFA_Calldown-regulatesRREB1activatesR-2296-0.75723212Pr-9
RNASeq_MAFB_Calldown-regulatesRREB1activatesR-2296-0.75723212Pr-9
t(4;14)down-regulatesRREB1activatesR-2296-0.75723212Pr-9
SETD2down-regulatesRREB1activatesR-2296-0.75723212Pr-9
TACC2down-regulatesRREB1activatesR-2296-0.75723212Pr-9
t(4;14)_cytogeneticdown-regulatesRREB1activatesR-2296-0.75723212Pr-9
FAT3up-regulatesRARBrepressesR-1107-0.7770968Pr-9
MAGI1up-regulatesRARBrepressesR-1107-0.7770968Pr-9
MYO10up-regulatesRARBrepressesR-1107-0.7770968Pr-9
PTPRDup-regulatesRARBrepressesR-1107-0.7770968Pr-9
SYNE1up-regulatesRARBrepressesR-1107-0.7770968Pr-9
TACC2up-regulatesRARBrepressesR-1107-0.7770968Pr-9
UBR4up-regulatesRARBrepressesR-1107-0.7770968Pr-9
ZNF462up-regulatesRARBrepressesR-1107-0.7770968Pr-9
t(14;16)_cytogeneticup-regulatesRARBrepressesR-1107-0.7770968Pr-9
AHNAK2down-regulatesRARAactivatesR-159-0.86094113Pr-9
MAGI1down-regulatesRARAactivatesR-159-0.86094113Pr-9
MAXdown-regulatesRARAactivatesR-159-0.86094113Pr-9
MYO10down-regulatesRARAactivatesR-159-0.86094113Pr-9
PCDH10down-regulatesRARAactivatesR-159-0.86094113Pr-9
t(11;14)up-regulatesRARAactivatesR-159-0.86094113Pr-9
TACC2down-regulatesRARAactivatesR-159-0.86094113Pr-9
del17down-regulatesRARAactivatesR-159-0.86094113Pr-9
t(14;16)_cytogeneticdown-regulatesRARAactivatesR-159-0.86094113Pr-9
AHNAK2down-regulatesHSF1activatesR-52-0.8759629Pr-9
DCHS1down-regulatesHSF1activatesR-52-0.8759629Pr-9
DIS3down-regulatesHSF1activatesR-52-0.8759629Pr-9
FAT3down-regulatesHSF1activatesR-52-0.8759629Pr-9
MACF1down-regulatesHSF1activatesR-52-0.8759629Pr-9
MAGI1down-regulatesHSF1activatesR-52-0.8759629Pr-9
MAXdown-regulatesHSF1activatesR-52-0.8759629Pr-9
MYO10down-regulatesHSF1activatesR-52-0.8759629Pr-9
NEBdown-regulatesHSF1activatesR-52-0.8759629Pr-9
PTPRDdown-regulatesHSF1activatesR-52-0.8759629Pr-9
RNASeq_CCND2_Calldown-regulatesHSF1activatesR-52-0.8759629Pr-9
RNASeq_FGFR3_Calldown-regulatesHSF1activatesR-52-0.8759629Pr-9
RNASeq_MAFB_Calldown-regulatesHSF1activatesR-52-0.8759629Pr-9
SETD2down-regulatesHSF1activatesR-52-0.8759629Pr-9
TACC2down-regulatesHSF1activatesR-52-0.8759629Pr-9
t(14;16)_cytogeneticdown-regulatesHSF1activatesR-52-0.8759629Pr-9
AHNAK2up-regulatesZBTB3repressesR-1264-0.88509313Pr-9
CMYA5up-regulatesZBTB3repressesR-1264-0.88509313Pr-9
NEBup-regulatesZBTB3repressesR-1264-0.88509313Pr-9
PTPRDup-regulatesZBTB3repressesR-1264-0.88509313Pr-9
t(11;14)down-regulatesZBTB3repressesR-1264-0.88509313Pr-9
SDK1up-regulatesZBTB3repressesR-1264-0.88509313Pr-9
TACC2up-regulatesZBTB3repressesR-1264-0.88509313Pr-9
del13down-regulatesZBTB3repressesR-1264-0.88509313Pr-9
t(14;16)_cytogeneticup-regulatesZBTB3repressesR-1264-0.88509313Pr-9
FAT3down-regulatesETS1activatesR-4-0.88612711Pr-9
MAXdown-regulatesETS1activatesR-4-0.88612711Pr-9
RNASeq_CCND2_Calldown-regulatesETS1activatesR-4-0.88612711Pr-9
RNASeq_FGFR3_Calldown-regulatesETS1activatesR-4-0.88612711Pr-9
t(4;14)down-regulatesETS1activatesR-4-0.88612711Pr-9
t(4;14)_cytogeneticdown-regulatesETS1activatesR-4-0.88612711Pr-9
AHNAK2down-regulatesGABPB1activatesR-1953-0.9586757Pr-9
FAT3down-regulatesGABPB1activatesR-1953-0.9586757Pr-9
MAGI1down-regulatesGABPB1activatesR-1953-0.9586757Pr-9
MYO10down-regulatesGABPB1activatesR-1953-0.9586757Pr-9
NEBdown-regulatesGABPB1activatesR-1953-0.9586757Pr-9
PTPRDdown-regulatesGABPB1activatesR-1953-0.9586757Pr-9
t(11;14)up-regulatesGABPB1activatesR-1953-0.9586757Pr-9
TACC2down-regulatesGABPB1activatesR-1953-0.9586757Pr-9
AHNAK2down-regulatesNR4A2activatesR-1718-1.00548Pr-9
CMYA5down-regulatesNR4A2activatesR-1718-1.00548Pr-9
FAT3down-regulatesNR4A2activatesR-1718-1.00548Pr-9
MACF1down-regulatesNR4A2activatesR-1718-1.00548Pr-9
RNASeq_FGFR3_Calldown-regulatesNR4A2activatesR-1718-1.00548Pr-9
t(4;14)down-regulatesNR4A2activatesR-1718-1.00548Pr-9
TACC2down-regulatesNR4A2activatesR-1718-1.00548Pr-9
AHNAK2down-regulatesCREB1activatesR-273-1.054928Pr-9
CMYA5down-regulatesCREB1activatesR-273-1.054928Pr-9
CYLDup-regulatesCREB1activatesR-273-1.054928Pr-9
DNAH5down-regulatesCREB1activatesR-273-1.054928Pr-9
FAT3down-regulatesCREB1activatesR-273-1.054928Pr-9
MAXdown-regulatesCREB1activatesR-273-1.054928Pr-9
RNASeq_CCND2_Calldown-regulatesCREB1activatesR-273-1.054928Pr-9
LRP2down-regulatesSTAT5AactivatesR-2166-1.0603310Pr-9
NEBdown-regulatesSTAT5AactivatesR-2166-1.0603310Pr-9
t(11;14)up-regulatesSTAT5AactivatesR-2166-1.0603310Pr-9
TRAF3down-regulatesSTAT5AactivatesR-2166-1.0603310Pr-9
AHNAK2up-regulatesSP1repressesR-2728-1.1202318Pr-9
DCHS1up-regulatesSP1repressesR-2728-1.1202318Pr-9
DIS3up-regulatesSP1repressesR-2728-1.1202318Pr-9
FAT3up-regulatesSP1repressesR-2728-1.1202318Pr-9
PTPRDup-regulatesSP1repressesR-2728-1.1202318Pr-9
RNASeq_FGFR3_Callup-regulatesSP1repressesR-2728-1.1202318Pr-9
RNASeq_MAFA_Callup-regulatesSP1repressesR-2728-1.1202318Pr-9
RNASeq_MAFB_Callup-regulatesSP1repressesR-2728-1.1202318Pr-9
t(4;14)up-regulatesSP1repressesR-2728-1.1202318Pr-9
SVILup-regulatesSP1repressesR-2728-1.1202318Pr-9
TRAF3up-regulatesSP1repressesR-2728-1.1202318Pr-9
UBR4up-regulatesSP1repressesR-2728-1.1202318Pr-9
t(14;16)_cytogeneticup-regulatesSP1repressesR-2728-1.1202318Pr-9
t(4;14)_cytogeneticup-regulatesSP1repressesR-2728-1.1202318Pr-9
AHNAK2down-regulatesIRF1activatesR-195-1.149616Pr-9
NRASup-regulatesIRF1activatesR-195-1.149616Pr-9
t(11;14)up-regulatesIRF1activatesR-195-1.149616Pr-9
TRAF3down-regulatesIRF1activatesR-195-1.149616Pr-9
AHNAK2up-regulatesARID3ArepressesR-1344-1.1554510Pr-9
KRASdown-regulatesARID3ArepressesR-1344-1.1554510Pr-9
NRASdown-regulatesARID3ArepressesR-1344-1.1554510Pr-9
t(11;14)down-regulatesARID3ArepressesR-1344-1.1554510Pr-9
RNASeq_MAFA_Callup-regulatesARID3ArepressesR-1344-1.1554510Pr-9
TRAF3up-regulatesARID3ArepressesR-1344-1.1554510Pr-9
t(14;16)_cytogeneticup-regulatesARID3ArepressesR-1344-1.1554510Pr-9
AHNAK2up-regulatesMAZrepressesR-503-1.1947412Pr-9
DCHS1up-regulatesMAZrepressesR-503-1.1947412Pr-9
FAT3up-regulatesMAZrepressesR-503-1.1947412Pr-9
MACF1up-regulatesMAZrepressesR-503-1.1947412Pr-9
RNASeq_FGFR3_Callup-regulatesMAZrepressesR-503-1.1947412Pr-9
RNASeq_MAFA_Callup-regulatesMAZrepressesR-503-1.1947412Pr-9
t(4;14)up-regulatesMAZrepressesR-503-1.1947412Pr-9
TRAF3up-regulatesMAZrepressesR-503-1.1947412Pr-9
t(14;16)_cytogeneticup-regulatesMAZrepressesR-503-1.1947412Pr-9
t(4;14)_cytogeneticup-regulatesMAZrepressesR-503-1.1947412Pr-9
MAGI1down-regulatesSPI1activatesR-2613-1.1996417Pr-9
NEBdown-regulatesSPI1activatesR-2613-1.1996417Pr-9
PTPRDdown-regulatesSPI1activatesR-2613-1.1996417Pr-9
t(11;14)up-regulatesSPI1activatesR-2613-1.1996417Pr-9
RNASeq_FGFR3_Calldown-regulatesSPI1activatesR-2613-1.1996417Pr-9
t(4;14)down-regulatesSPI1activatesR-2613-1.1996417Pr-9
TRAF3down-regulatesSPI1activatesR-2613-1.1996417Pr-9
t(14;16)_cytogeneticdown-regulatesSPI1activatesR-2613-1.1996417Pr-9
AHNAK2down-regulatesMEF2AactivatesR-1878-1.2492120Pr-9
DCHS1down-regulatesMEF2AactivatesR-1878-1.2492120Pr-9
DIS3down-regulatesMEF2AactivatesR-1878-1.2492120Pr-9
FAT3down-regulatesMEF2AactivatesR-1878-1.2492120Pr-9
MACF1down-regulatesMEF2AactivatesR-1878-1.2492120Pr-9
MAGI1down-regulatesMEF2AactivatesR-1878-1.2492120Pr-9
MAXdown-regulatesMEF2AactivatesR-1878-1.2492120Pr-9
MYO10down-regulatesMEF2AactivatesR-1878-1.2492120Pr-9
NRASup-regulatesMEF2AactivatesR-1878-1.2492120Pr-9
PTPRDdown-regulatesMEF2AactivatesR-1878-1.2492120Pr-9
RNASeq_CCND2_Calldown-regulatesMEF2AactivatesR-1878-1.2492120Pr-9
RNASeq_FGFR3_Calldown-regulatesMEF2AactivatesR-1878-1.2492120Pr-9
RNASeq_MAFA_Calldown-regulatesMEF2AactivatesR-1878-1.2492120Pr-9
RNASeq_MAFB_Calldown-regulatesMEF2AactivatesR-1878-1.2492120Pr-9
t(4;14)down-regulatesMEF2AactivatesR-1878-1.2492120Pr-9
TACC2down-regulatesMEF2AactivatesR-1878-1.2492120Pr-9
t(14;16)_cytogeneticdown-regulatesMEF2AactivatesR-1878-1.2492120Pr-9
MAGI1down-regulatesBCL6activatesR-541-1.2580119Pr-9
NEBdown-regulatesBCL6activatesR-541-1.2580119Pr-9
t(11;14)up-regulatesBCL6activatesR-541-1.2580119Pr-9
del17down-regulatesBCL6activatesR-541-1.2580119Pr-9
t(14;16)_cytogeneticdown-regulatesBCL6activatesR-541-1.2580119Pr-9
AHNAK2down-regulatesMAFKactivatesR-2806-1.2799413Pr-9
DCHS1down-regulatesMAFKactivatesR-2806-1.2799413Pr-9
FAT3down-regulatesMAFKactivatesR-2806-1.2799413Pr-9
MACF1down-regulatesMAFKactivatesR-2806-1.2799413Pr-9
MAGI1down-regulatesMAFKactivatesR-2806-1.2799413Pr-9
MYO10down-regulatesMAFKactivatesR-2806-1.2799413Pr-9
NEBdown-regulatesMAFKactivatesR-2806-1.2799413Pr-9
PCDH10down-regulatesMAFKactivatesR-2806-1.2799413Pr-9
PTPRDdown-regulatesMAFKactivatesR-2806-1.2799413Pr-9
RNASeq_MAFA_Calldown-regulatesMAFKactivatesR-2806-1.2799413Pr-9
TACC2down-regulatesMAFKactivatesR-2806-1.2799413Pr-9
AHNAK2down-regulatesNFKB1activatesR-1583-1.3856410Pr-9
DCHS1down-regulatesNFKB1activatesR-1583-1.3856410Pr-9
FAT3down-regulatesNFKB1activatesR-1583-1.3856410Pr-9
MACF1down-regulatesNFKB1activatesR-1583-1.3856410Pr-9
MAGI1down-regulatesNFKB1activatesR-1583-1.3856410Pr-9
MAXdown-regulatesNFKB1activatesR-1583-1.3856410Pr-9
MYO10down-regulatesNFKB1activatesR-1583-1.3856410Pr-9
PCDH10down-regulatesNFKB1activatesR-1583-1.3856410Pr-9
PTPRDdown-regulatesNFKB1activatesR-1583-1.3856410Pr-9
RNASeq_CCND2_Calldown-regulatesNFKB1activatesR-1583-1.3856410Pr-9
RNASeq_FGFR3_Calldown-regulatesNFKB1activatesR-1583-1.3856410Pr-9
RNASeq_MAFB_Calldown-regulatesNFKB1activatesR-1583-1.3856410Pr-9
t(4;14)down-regulatesNFKB1activatesR-1583-1.3856410Pr-9
TACC2down-regulatesNFKB1activatesR-1583-1.3856410Pr-9
ZFHX3down-regulatesNFKB1activatesR-1583-1.3856410Pr-9
t(4;14)_cytogeneticdown-regulatesNFKB1activatesR-1583-1.3856410Pr-9
AHNAK2down-regulatesELF4activatesR-2340-1.4011818Pr-9
PCDH10down-regulatesELF4activatesR-2340-1.4011818Pr-9
t(11;14)up-regulatesELF4activatesR-2340-1.4011818Pr-9
TRAF3down-regulatesELF4activatesR-2340-1.4011818Pr-9
DCHS1down-regulatesELF3activatesR-2143-1.4011818Pr-9
FAT3down-regulatesELF3activatesR-2143-1.4011818Pr-9
t(11;14)up-regulatesELF3activatesR-2143-1.4011818Pr-9
TACC2down-regulatesELF3activatesR-2143-1.4011818Pr-9
del17down-regulatesELF3activatesR-2143-1.4011818Pr-9
AHNAK2down-regulatesZNF281activatesR-2480-1.4130818Pr-9
CMYA5down-regulatesZNF281activatesR-2480-1.4130818Pr-9
FAT3down-regulatesZNF281activatesR-2480-1.4130818Pr-9
MACF1down-regulatesZNF281activatesR-2480-1.4130818Pr-9
PCDH10down-regulatesZNF281activatesR-2480-1.4130818Pr-9
PTPRDdown-regulatesZNF281activatesR-2480-1.4130818Pr-9
t(11;14)up-regulatesZNF281activatesR-2480-1.4130818Pr-9
RNASeq_MAFB_Calldown-regulatesZNF281activatesR-2480-1.4130818Pr-9
TACC2down-regulatesZNF281activatesR-2480-1.4130818Pr-9
AHNAK2down-regulatesFOXO1activatesR-1408-1.4269416Pr-9
DCHS1down-regulatesFOXO1activatesR-1408-1.4269416Pr-9
FAT3down-regulatesFOXO1activatesR-1408-1.4269416Pr-9
MACF1down-regulatesFOXO1activatesR-1408-1.4269416Pr-9
MAGI1down-regulatesFOXO1activatesR-1408-1.4269416Pr-9
MYO10down-regulatesFOXO1activatesR-1408-1.4269416Pr-9
NEBdown-regulatesFOXO1activatesR-1408-1.4269416Pr-9
PTPRDdown-regulatesFOXO1activatesR-1408-1.4269416Pr-9
t(11;14)up-regulatesFOXO1activatesR-1408-1.4269416Pr-9
RNASeq_MAFA_Calldown-regulatesFOXO1activatesR-1408-1.4269416Pr-9
RNASeq_MAFB_Calldown-regulatesFOXO1activatesR-1408-1.4269416Pr-9
SVILdown-regulatesFOXO1activatesR-1408-1.4269416Pr-9
TACC2down-regulatesFOXO1activatesR-1408-1.4269416Pr-9
t(14;16)_cytogeneticdown-regulatesFOXO1activatesR-1408-1.4269416Pr-9
AHNAK2down-regulatesRFX1activatesR-2570-1.432367Pr-9
CMYA5down-regulatesRFX1activatesR-2570-1.432367Pr-9
MACF1down-regulatesRFX1activatesR-2570-1.432367Pr-9
t(11;14)up-regulatesRFX1activatesR-2570-1.432367Pr-9
SYNE1down-regulatesRFX1activatesR-2570-1.432367Pr-9
t(11;14)_cytogeneticup-regulatesRFX1activatesR-2570-1.432367Pr-9
MAXup-regulatesTCF3repressesR-2061-1.4477320Pr-9
AHNAK2down-regulatesSTAT4activatesR-2654-1.4661910Pr-9
KRASup-regulatesSTAT4activatesR-2654-1.4661910Pr-9
PTPRDdown-regulatesSTAT4activatesR-2654-1.4661910Pr-9
SVILdown-regulatesSTAT4activatesR-2654-1.4661910Pr-9
TRAF3down-regulatesSTAT4activatesR-2654-1.4661910Pr-9
RNASeq_FGFR3_Callup-regulatesNFYArepressesR-1476-1.473259Pr-9
t(4;14)up-regulatesNFYArepressesR-1476-1.473259Pr-9
t(4;14)_cytogeneticup-regulatesNFYArepressesR-1476-1.473259Pr-9
AHNAK2down-regulatesCEBPGactivatesR-442-1.5598911Pr-9
FAT3down-regulatesCEBPGactivatesR-442-1.5598911Pr-9
MACF1down-regulatesCEBPGactivatesR-442-1.5598911Pr-9
MAGI1down-re