Causal Mechanistic Flows with regulons in program Pr-77
| Mutation | Role | Regulator | Role | Regulon | Hazard Ratio | # regulon genes | Transcriptional Program |
|---|---|---|---|---|---|---|---|
| DCHS1 | down-regulates | FOXK1 | activates | R-1204 | 3.06585 | 10 | Pr-77 |
| FAT3 | down-regulates | FOXK1 | activates | R-1204 | 3.06585 | 10 | Pr-77 |
| MAGI1 | down-regulates | FOXK1 | activates | R-1204 | 3.06585 | 10 | Pr-77 |
| RNASeq_MAFA_Call | down-regulates | FOXK1 | activates | R-1204 | 3.06585 | 10 | Pr-77 |
| COL6A5 | down-regulates | ENSG00000078399 | activates | R-2842 | 3.78355 | 10 | Pr-77 |
| t(11;14) | up-regulates | ENSG00000078399 | activates | R-2842 | 3.78355 | 10 | Pr-77 |
| DIS3 | down-regulates | SOX7 | represses | R-1300 | 4.16587 | 15 | Pr-77 |
| NEB | up-regulates | SOX7 | represses | R-1300 | 4.16587 | 15 | Pr-77 |
| PRKD2 | down-regulates | SOX7 | represses | R-1300 | 4.16587 | 15 | Pr-77 |
| RNASeq_FGFR3_Call | down-regulates | SOX7 | represses | R-1300 | 4.16587 | 15 | Pr-77 |
| t(4;14) | down-regulates | SOX7 | represses | R-1300 | 4.16587 | 15 | Pr-77 |
| amp1q | down-regulates | SOX7 | represses | R-1300 | 4.16587 | 15 | Pr-77 |
| del1p | down-regulates | SOX7 | represses | R-1300 | 4.16587 | 15 | Pr-77 |
| NEB | up-regulates | PAX6 | represses | R-1549 | 4.66957 | 13 | Pr-77 |
| PRKD2 | down-regulates | PAX6 | represses | R-1549 | 4.66957 | 13 | Pr-77 |
| t(11;14) | down-regulates | PAX6 | represses | R-1549 | 4.66957 | 13 | Pr-77 |
| RNASeq_FGFR3_Call | down-regulates | PAX6 | represses | R-1549 | 4.66957 | 13 | Pr-77 |
| t(4;14) | down-regulates | PAX6 | represses | R-1549 | 4.66957 | 13 | Pr-77 |
| amp1q | down-regulates | PAX6 | represses | R-1549 | 4.66957 | 13 | Pr-77 |
Genes in program Pr-77
| EnsEMBL Id | Entrez Id | Preferred |
|---|
