Regulator – Multiple Myeloma Network Portal

Summary of regulator annotations and link-out to annotation databases

Basic gene annotations are collected from Uniprot and displayed with links to original sources. A quick link to explore the genomic context with Uniprot Browser is available.

E2F2 - E2F transcription factor 2

Uniprot Browser

Entrez ID	EnsEMBL ID	Preferred Name	Uniprot ID
1870	ENSG00000282899	E2F2	Q14209

List of causal flows containing the regulator.

Causal Flows are statistically significant links between putative causal events (somatic mutations, copy number variations, chromosomal translocations, etc.) and the activity levels of regulators and regulons. In the causal flow, a mutation may causally activate or deactivate a downstream regulator which then might up- down-regulates a regulonthat contains genes with similar expression profiles and binding sites.

Causal Mechanistic Flows for Regulator: E2F2

Mutation	Regulator	Role	Regulon	Cox Hazard Ratio	Transcriptional Program
CMYA5	E2F2	represses	R-2943	-0.530398	Pr-58 Genes (28) ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28) R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148
DNAH5	E2F2	represses	R-2943	-0.530398	Pr-58 Genes (28) ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28) R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148
MACF1	E2F2	represses	R-2943	-0.530398	Pr-58 Genes (28) ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28) R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148
MUC12	E2F2	represses	R-2943	-0.530398	Pr-58 Genes (28) ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28) R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148
RELN	E2F2	represses	R-2943	-0.530398	Pr-58 Genes (28) ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28) R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148
RNASeq_FGFR3_Call	E2F2	represses	R-2943	-0.530398	Pr-58 Genes (28) ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28) R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148
t(14;16)	E2F2	represses	R-2943	-0.530398	Pr-58 Genes (28) ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28) R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148
MYC	E2F2	represses	R-2943	-0.530398	Pr-58 Genes (28) ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28) R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148
t(4;14)	E2F2	represses	R-2943	-0.530398	Pr-58 Genes (28) ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28) R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148
TP53	E2F2	represses	R-2943	-0.530398	Pr-58 Genes (28) ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28) R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148
amp1q	E2F2	represses	R-2943	-0.530398	Pr-58 Genes (28) ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28) R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148
del17	E2F2	represses	R-2943	-0.530398	Pr-58 Genes (28) ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28) R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148
del17p	E2F2	represses	R-2943	-0.530398	Pr-58 Genes (28) ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28) R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148
FAT3	E2F2	represses	R-2946	-1.27434	Pr-15 Genes (14) RBM33, RUFY4, SLC39A10, RPE, GLMP, MSRB1, BMPR2, SIPA1, VDAC1, EIF6, STON1, PRKDC Regulons (22) R-2088, R-2040, R-2207, R-282, R-2251, R-2946, R-1593, R-2737, R-1470, R-1848, R-1263, R-297, R-989, R-36, R-1782, R-1427, R-2049, R-2191, R-2288, R-1104, R-149, R-2959
TP53	E2F2	represses	R-2946	-1.27434	Pr-15 Genes (14) RBM33, RUFY4, SLC39A10, RPE, GLMP, MSRB1, BMPR2, SIPA1, VDAC1, EIF6, STON1, PRKDC Regulons (22) R-2088, R-2040, R-2207, R-282, R-2251, R-2946, R-1593, R-2737, R-1470, R-1848, R-1263, R-297, R-989, R-36, R-1782, R-1427, R-2049, R-2191, R-2288, R-1104, R-149, R-2959
AHNAK2	E2F2	represses	R-2949	1.40408	Pr-16 Genes (20) NR2C2, LOC653513, C11orf54, ZNRF3, NSMCE3, LRRC70, TAF9B, B3GLCT, ZNF775, PPTC7, TRIM33, SIPA1L1, ZNF460, ZNF790, ZKSCAN8, CEP290, CIPC, GIMAP1, LILRA6, CHMP4A Regulons (20) R-383, R-191, R-50, R-872, R-1431, R-1919, R-1532, R-1546, R-2884, R-84, R-2290, R-666, R-1935, R-3128, R-1871, R-2949, R-2227, R-156, R-1279, R-2522
FAT3	E2F2	represses	R-2949	1.40408	Pr-16 Genes (20) NR2C2, LOC653513, C11orf54, ZNRF3, NSMCE3, LRRC70, TAF9B, B3GLCT, ZNF775, PPTC7, TRIM33, SIPA1L1, ZNF460, ZNF790, ZKSCAN8, CEP290, CIPC, GIMAP1, LILRA6, CHMP4A Regulons (20) R-383, R-191, R-50, R-872, R-1431, R-1919, R-1532, R-1546, R-2884, R-84, R-2290, R-666, R-1935, R-3128, R-1871, R-2949, R-2227, R-156, R-1279, R-2522
MAX	E2F2	represses	R-2949	1.40408	Pr-16 Genes (20) NR2C2, LOC653513, C11orf54, ZNRF3, NSMCE3, LRRC70, TAF9B, B3GLCT, ZNF775, PPTC7, TRIM33, SIPA1L1, ZNF460, ZNF790, ZKSCAN8, CEP290, CIPC, GIMAP1, LILRA6, CHMP4A Regulons (20) R-383, R-191, R-50, R-872, R-1431, R-1919, R-1532, R-1546, R-2884, R-84, R-2290, R-666, R-1935, R-3128, R-1871, R-2949, R-2227, R-156, R-1279, R-2522
PTPRD	E2F2	represses	R-2949	1.40408	Pr-16 Genes (20) NR2C2, LOC653513, C11orf54, ZNRF3, NSMCE3, LRRC70, TAF9B, B3GLCT, ZNF775, PPTC7, TRIM33, SIPA1L1, ZNF460, ZNF790, ZKSCAN8, CEP290, CIPC, GIMAP1, LILRA6, CHMP4A Regulons (20) R-383, R-191, R-50, R-872, R-1431, R-1919, R-1532, R-1546, R-2884, R-84, R-2290, R-666, R-1935, R-3128, R-1871, R-2949, R-2227, R-156, R-1279, R-2522
SVIL	E2F2	represses	R-2949	1.40408	Pr-16 Genes (20) NR2C2, LOC653513, C11orf54, ZNRF3, NSMCE3, LRRC70, TAF9B, B3GLCT, ZNF775, PPTC7, TRIM33, SIPA1L1, ZNF460, ZNF790, ZKSCAN8, CEP290, CIPC, GIMAP1, LILRA6, CHMP4A Regulons (20) R-383, R-191, R-50, R-872, R-1431, R-1919, R-1532, R-1546, R-2884, R-84, R-2290, R-666, R-1935, R-3128, R-1871, R-2949, R-2227, R-156, R-1279, R-2522
TACC2	E2F2	represses	R-2949	1.40408	Pr-16 Genes (20) NR2C2, LOC653513, C11orf54, ZNRF3, NSMCE3, LRRC70, TAF9B, B3GLCT, ZNF775, PPTC7, TRIM33, SIPA1L1, ZNF460, ZNF790, ZKSCAN8, CEP290, CIPC, GIMAP1, LILRA6, CHMP4A Regulons (20) R-383, R-191, R-50, R-872, R-1431, R-1919, R-1532, R-1546, R-2884, R-84, R-2290, R-666, R-1935, R-3128, R-1871, R-2949, R-2227, R-156, R-1279, R-2522
DCHS1	E2F2	activates	R-2947	-1.79304	Pr-102 Genes (10) CCR4, KPNA4, NANOS3, NHLRC1, HIST3H2BB, DDX42, SH3D21, ZNF345, PINX1, CCPG1 Regulons (13) R-367, R-985, R-553, R-2155, R-2062, R-1380, R-2947, R-1355, R-1937, R-3060, R-769, R-522, R-2706
DNAH5	E2F2	activates	R-2947	-1.79304	Pr-102 Genes (10) CCR4, KPNA4, NANOS3, NHLRC1, HIST3H2BB, DDX42, SH3D21, ZNF345, PINX1, CCPG1 Regulons (13) R-367, R-985, R-553, R-2155, R-2062, R-1380, R-2947, R-1355, R-1937, R-3060, R-769, R-522, R-2706
FAT3	E2F2	activates	R-2947	-1.79304	Pr-102 Genes (10) CCR4, KPNA4, NANOS3, NHLRC1, HIST3H2BB, DDX42, SH3D21, ZNF345, PINX1, CCPG1 Regulons (13) R-367, R-985, R-553, R-2155, R-2062, R-1380, R-2947, R-1355, R-1937, R-3060, R-769, R-522, R-2706
MAX	E2F2	activates	R-2947	-1.79304	Pr-102 Genes (10) CCR4, KPNA4, NANOS3, NHLRC1, HIST3H2BB, DDX42, SH3D21, ZNF345, PINX1, CCPG1 Regulons (13) R-367, R-985, R-553, R-2155, R-2062, R-1380, R-2947, R-1355, R-1937, R-3060, R-769, R-522, R-2706
PTPRD	E2F2	activates	R-2947	-1.79304	Pr-102 Genes (10) CCR4, KPNA4, NANOS3, NHLRC1, HIST3H2BB, DDX42, SH3D21, ZNF345, PINX1, CCPG1 Regulons (13) R-367, R-985, R-553, R-2155, R-2062, R-1380, R-2947, R-1355, R-1937, R-3060, R-769, R-522, R-2706
DNAH10	E2F2	activates	R-2945	1.88745	Pr-133 Genes (6) UCP3, GJD4, ACOT4, HNRNPA0, ZCWPW2 Regulons (7) R-3071, R-1940, R-2231, R-372, R-2200, R-2945, R-2989
DNAH5	E2F2	activates	R-2945	1.88745	Pr-133 Genes (6) UCP3, GJD4, ACOT4, HNRNPA0, ZCWPW2 Regulons (7) R-3071, R-1940, R-2231, R-372, R-2200, R-2945, R-2989
FAT3	E2F2	activates	R-2945	1.88745	Pr-133 Genes (6) UCP3, GJD4, ACOT4, HNRNPA0, ZCWPW2 Regulons (7) R-3071, R-1940, R-2231, R-372, R-2200, R-2945, R-2989
MACF1	E2F2	activates	R-2945	1.88745	Pr-133 Genes (6) UCP3, GJD4, ACOT4, HNRNPA0, ZCWPW2 Regulons (7) R-3071, R-1940, R-2231, R-372, R-2200, R-2945, R-2989
RNASeq_MAFA_Call	E2F2	activates	R-2945	1.88745	Pr-133 Genes (6) UCP3, GJD4, ACOT4, HNRNPA0, ZCWPW2 Regulons (7) R-3071, R-1940, R-2231, R-372, R-2200, R-2945, R-2989
RNASeq_MAFB_Call	E2F2	activates	R-2945	1.88745	Pr-133 Genes (6) UCP3, GJD4, ACOT4, HNRNPA0, ZCWPW2 Regulons (7) R-3071, R-1940, R-2231, R-372, R-2200, R-2945, R-2989
t(14;16)	E2F2	activates	R-2945	1.88745	Pr-133 Genes (6) UCP3, GJD4, ACOT4, HNRNPA0, ZCWPW2 Regulons (7) R-3071, R-1940, R-2231, R-372, R-2200, R-2945, R-2989
SYNE1	E2F2	activates	R-2945	1.88745	Pr-133 Genes (6) UCP3, GJD4, ACOT4, HNRNPA0, ZCWPW2 Regulons (7) R-3071, R-1940, R-2231, R-372, R-2200, R-2945, R-2989
TP53	E2F2	activates	R-2945	1.88745	Pr-133 Genes (6) UCP3, GJD4, ACOT4, HNRNPA0, ZCWPW2 Regulons (7) R-3071, R-1940, R-2231, R-372, R-2200, R-2945, R-2989
del17	E2F2	activates	R-2945	1.88745	Pr-133 Genes (6) UCP3, GJD4, ACOT4, HNRNPA0, ZCWPW2 Regulons (7) R-3071, R-1940, R-2231, R-372, R-2200, R-2945, R-2989
t(14;16)_cytogenetic	E2F2	activates	R-2945	1.88745	Pr-133 Genes (6) UCP3, GJD4, ACOT4, HNRNPA0, ZCWPW2 Regulons (7) R-3071, R-1940, R-2231, R-372, R-2200, R-2945, R-2989
AHNAK2	E2F2	represses	R-2948	-3.01545	Pr-44 Genes (0) Regulons (7) R-1193, R-513, R-2948, R-1851, R-3018, R-332, R-280
DCHS1	E2F2	represses	R-2948	-3.01545	Pr-44 Genes (0) Regulons (7) R-1193, R-513, R-2948, R-1851, R-3018, R-332, R-280
DIS3	E2F2	represses	R-2948	-3.01545	Pr-44 Genes (0) Regulons (7) R-1193, R-513, R-2948, R-1851, R-3018, R-332, R-280
FAM46C	E2F2	represses	R-2948	-3.01545	Pr-44 Genes (0) Regulons (7) R-1193, R-513, R-2948, R-1851, R-3018, R-332, R-280
FAT3	E2F2	represses	R-2948	-3.01545	Pr-44 Genes (0) Regulons (7) R-1193, R-513, R-2948, R-1851, R-3018, R-332, R-280
MAX	E2F2	represses	R-2948	-3.01545	Pr-44 Genes (0) Regulons (7) R-1193, R-513, R-2948, R-1851, R-3018, R-332, R-280
MUC12	E2F2	represses	R-2948	-3.01545	Pr-44 Genes (0) Regulons (7) R-1193, R-513, R-2948, R-1851, R-3018, R-332, R-280
RNASeq_FGFR3_Call	E2F2	represses	R-2948	-3.01545	Pr-44 Genes (0) Regulons (7) R-1193, R-513, R-2948, R-1851, R-3018, R-332, R-280
RNASeq_MAFA_Call	E2F2	represses	R-2948	-3.01545	Pr-44 Genes (0) Regulons (7) R-1193, R-513, R-2948, R-1851, R-3018, R-332, R-280
t(14;16)	E2F2	represses	R-2948	-3.01545	Pr-44 Genes (0) Regulons (7) R-1193, R-513, R-2948, R-1851, R-3018, R-332, R-280
t(4;14)	E2F2	represses	R-2948	-3.01545	Pr-44 Genes (0) Regulons (7) R-1193, R-513, R-2948, R-1851, R-3018, R-332, R-280
ZNF462	E2F2	represses	R-2948	-3.01545	Pr-44 Genes (0) Regulons (7) R-1193, R-513, R-2948, R-1851, R-3018, R-332, R-280
t(4;14)_cytogenetic	E2F2	represses	R-2948	-3.01545	Pr-44 Genes (0) Regulons (7) R-1193, R-513, R-2948, R-1851, R-3018, R-332, R-280
AHNAK2	E2F2	activates	R-2942	8.59906	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
CMYA5	E2F2	activates	R-2942	8.59906	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
DMD	E2F2	activates	R-2942	8.59906	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
DNAH10	E2F2	activates	R-2942	8.59906	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
DNAH5	E2F2	activates	R-2942	8.59906	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
FAT3	E2F2	activates	R-2942	8.59906	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
MACF1	E2F2	activates	R-2942	8.59906	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
MAX	E2F2	activates	R-2942	8.59906	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
t(14;16)	E2F2	activates	R-2942	8.59906	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
MYC	E2F2	activates	R-2942	8.59906	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
SYNE1	E2F2	activates	R-2942	8.59906	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
TP53	E2F2	activates	R-2942	8.59906	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
TTN	E2F2	activates	R-2942	8.59906	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
ZNF208	E2F2	activates	R-2942	8.59906	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
ZNF462	E2F2	activates	R-2942	8.59906	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
del17	E2F2	activates	R-2942	8.59906	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
del17p	E2F2	activates	R-2942	8.59906	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
t(14;16)_cytogenetic	E2F2	activates	R-2942	8.59906	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
AHNAK2	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
CMYA5	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
DCHS1	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
DIS3	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
DMD	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
DNAH10	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
DNAH5	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
FAM46C	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
FAT3	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
MACF1	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
MAX	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
RELN	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
RNASeq_FGFR3_Call	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
RNASeq_MAFA_Call	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
RNASeq_MAFB_Call	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
t(14;16)	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
t(4;14)	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
SVIL	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
TACC2	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
TP53	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
TTN	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
ZNF208	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
ZNF462	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
amp1q	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
del17	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
del17p	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
t(14;16)_cytogenetic	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627
t(4;14)_cytogenetic	E2F2	activates	R-2944	8.90615	Pr-68 Genes (0) Regulons (18) R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627

E2F2 - E2F transcription factor 2

Causal Mechanistic Flows for Regulator: E2F2

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