Program

Causal Mechanistic Flows with regulons in program Pr-3

MutationRoleRegulatorRoleRegulonHazard Ratio# regulon genesTranscriptional Program
KIAA1244down-regulatesSPI1activatesR-26190.011471512Pr-3
NEBdown-regulatesSPI1activatesR-26190.011471512Pr-3
PTPRDdown-regulatesSPI1activatesR-26190.011471512Pr-3
t(11;14)up-regulatesSPI1activatesR-26190.011471512Pr-3
MYCdown-regulatesSPI1activatesR-26190.011471512Pr-3
t(4;14)down-regulatesSPI1activatesR-26190.011471512Pr-3
TRAF3down-regulatesSPI1activatesR-26190.011471512Pr-3
t(14;16)_cytogeneticdown-regulatesSPI1activatesR-26190.011471512Pr-3
CMYA5down-regulatesELF3activatesR-21480.074742112Pr-3
t(11;14)up-regulatesELF3activatesR-21480.074742112Pr-3
TACC2down-regulatesELF3activatesR-21480.074742112Pr-3
amp1qup-regulatesELF3activatesR-21480.074742112Pr-3
del13up-regulatesELF3activatesR-21480.074742112Pr-3
del17down-regulatesELF3activatesR-21480.074742112Pr-3
del17pdown-regulatesELF3activatesR-21480.074742112Pr-3
IRF4down-regulatesXBP1repressesR-30540.12847210Pr-3
NEBup-regulatesXBP1repressesR-30540.12847210Pr-3
PCDH7up-regulatesXBP1repressesR-30540.12847210Pr-3
t(11;14)down-regulatesXBP1repressesR-30540.12847210Pr-3
t(11;14)_cytogeneticdown-regulatesXBP1repressesR-30540.12847210Pr-3
t(14;16)_cytogeneticup-regulatesXBP1repressesR-30540.12847210Pr-3
AHNAK2down-regulatesATF3activatesR-2410-0.140549Pr-3
CMYA5down-regulatesATF3activatesR-2410-0.140549Pr-3
SYNE1down-regulatesATF3activatesR-2410-0.140549Pr-3
TP53down-regulatesATF3activatesR-2410-0.140549Pr-3
IRF4down-regulatesENSG00000105991repressesR-228-0.1854888Pr-3
t(11;14)down-regulatesENSG00000105991repressesR-228-0.1854888Pr-3
del13down-regulatesENSG00000105991repressesR-228-0.1854888Pr-3
t(11;14)_cytogeneticdown-regulatesENSG00000105991repressesR-228-0.1854888Pr-3
t(11;14)down-regulatesTCF4repressesR-30040.1958056Pr-3
t(11;14)_cytogeneticdown-regulatesTCF4repressesR-30040.1958056Pr-3
ABCA13down-regulatesFOXJ3activatesR-2876-0.29033535Pr-3
AHNAK2down-regulatesFOXJ3activatesR-2876-0.29033535Pr-3
CMYA5down-regulatesFOXJ3activatesR-2876-0.29033535Pr-3
DNAH5down-regulatesFOXJ3activatesR-2876-0.29033535Pr-3
MYO10down-regulatesFOXJ3activatesR-2876-0.29033535Pr-3
NEBdown-regulatesFOXJ3activatesR-2876-0.29033535Pr-3
PTPRDdown-regulatesFOXJ3activatesR-2876-0.29033535Pr-3
t(11;14)up-regulatesFOXJ3activatesR-2876-0.29033535Pr-3
RNASeq_MAFA_Calldown-regulatesFOXJ3activatesR-2876-0.29033535Pr-3
SYNE1down-regulatesFOXJ3activatesR-2876-0.29033535Pr-3
TACC2down-regulatesFOXJ3activatesR-2876-0.29033535Pr-3
del13up-regulatesFOXJ3activatesR-2876-0.29033535Pr-3
del17down-regulatesFOXJ3activatesR-2876-0.29033535Pr-3
del17pdown-regulatesFOXJ3activatesR-2876-0.29033535Pr-3
t(11;14)_cytogeneticup-regulatesFOXJ3activatesR-2876-0.29033535Pr-3
AHNAK2down-regulatesSF1activatesR-1907-0.3170148Pr-3
CMYA5down-regulatesSF1activatesR-1907-0.3170148Pr-3
DNAH5down-regulatesSF1activatesR-1907-0.3170148Pr-3
LRP2down-regulatesSF1activatesR-1907-0.3170148Pr-3
MACF1down-regulatesSF1activatesR-1907-0.3170148Pr-3
MAXdown-regulatesSF1activatesR-1907-0.3170148Pr-3
MUC12down-regulatesSF1activatesR-1907-0.3170148Pr-3
PCDH10down-regulatesSF1activatesR-1907-0.3170148Pr-3
t(11;14)up-regulatesSF1activatesR-1907-0.3170148Pr-3
ZFHX3down-regulatesSF1activatesR-1907-0.3170148Pr-3
ZNF208down-regulatesSF1activatesR-1907-0.3170148Pr-3
t(11;14)_cytogeneticup-regulatesSF1activatesR-1907-0.3170148Pr-3
AHNAK2down-regulatesFOXK1activatesR-1191-0.32019832Pr-3
MACF1down-regulatesFOXK1activatesR-1191-0.32019832Pr-3
MAGI1down-regulatesFOXK1activatesR-1191-0.32019832Pr-3
MYO10down-regulatesFOXK1activatesR-1191-0.32019832Pr-3
NEBdown-regulatesFOXK1activatesR-1191-0.32019832Pr-3
RNASeq_MAFA_Calldown-regulatesFOXK1activatesR-1191-0.32019832Pr-3
SYNE1down-regulatesFOXK1activatesR-1191-0.32019832Pr-3
TACC2down-regulatesFOXK1activatesR-1191-0.32019832Pr-3
del13up-regulatesFOXK1activatesR-1191-0.32019832Pr-3
DMDup-regulatesZNF281activatesR-24900.32479Pr-3
NEBdown-regulatesZNF281activatesR-24900.32479Pr-3
PTPRDdown-regulatesZNF281activatesR-24900.32479Pr-3
t(11;14)up-regulatesZNF281activatesR-24900.32479Pr-3
SYNE1down-regulatesZNF281activatesR-24900.32479Pr-3
TACC2down-regulatesZNF281activatesR-24900.32479Pr-3
del13up-regulatesZNF281activatesR-24900.32479Pr-3
t(11;14)_cytogeneticup-regulatesZNF281activatesR-24900.32479Pr-3
ABCA13down-regulatesFOXO3activatesR-2769-0.33693933Pr-3
RNASeq_MAFA_Calldown-regulatesFOXO3activatesR-2769-0.33693933Pr-3
MAGI1down-regulatesENSG00000054598activatesR-1000-0.38014533Pr-3
NEBdown-regulatesENSG00000054598activatesR-1000-0.38014533Pr-3
PTPRDdown-regulatesENSG00000054598activatesR-1000-0.38014533Pr-3
t(11;14)up-regulatesENSG00000054598activatesR-1000-0.38014533Pr-3
del17down-regulatesENSG00000054598activatesR-1000-0.38014533Pr-3
AHNAK2down-regulatesFOXP1activatesR-3121-0.41725835Pr-3
PCDH10down-regulatesFOXP1activatesR-3121-0.41725835Pr-3
PCDH7down-regulatesFOXP1activatesR-3121-0.41725835Pr-3
t(11;14)up-regulatesFOXP1activatesR-3121-0.41725835Pr-3
TACC2down-regulatesFOXP1activatesR-3121-0.41725835Pr-3
del13up-regulatesFOXP1activatesR-3121-0.41725835Pr-3
t(11;14)_cytogeneticup-regulatesFOXP1activatesR-3121-0.41725835Pr-3
AHNAK2up-regulatesZBTB3repressesR-1275-0.4219616Pr-3
CMYA5up-regulatesZBTB3repressesR-1275-0.4219616Pr-3
CSMD3up-regulatesZBTB3repressesR-1275-0.4219616Pr-3
IRF4down-regulatesZBTB3repressesR-1275-0.4219616Pr-3
NEBup-regulatesZBTB3repressesR-1275-0.4219616Pr-3
t(11;14)down-regulatesZBTB3repressesR-1275-0.4219616Pr-3
MYCup-regulatesZBTB3repressesR-1275-0.4219616Pr-3
SDK1up-regulatesZBTB3repressesR-1275-0.4219616Pr-3
TACC2up-regulatesZBTB3repressesR-1275-0.4219616Pr-3
XIRP2up-regulatesZBTB3repressesR-1275-0.4219616Pr-3
del13down-regulatesZBTB3repressesR-1275-0.4219616Pr-3
t(11;14)_cytogeneticdown-regulatesZBTB3repressesR-1275-0.4219616Pr-3
t(14;16)_cytogeneticup-regulatesZBTB3repressesR-1275-0.4219616Pr-3
DIS3down-regulatesHOXA5repressesR-22-0.43692810Pr-3
IRF4down-regulatesHOXA5repressesR-22-0.43692810Pr-3
t(11;14)down-regulatesHOXA5repressesR-22-0.43692810Pr-3
del17pup-regulatesHOXA5repressesR-22-0.43692810Pr-3
t(11;14)_cytogeneticdown-regulatesHOXA5repressesR-22-0.43692810Pr-3
DCHS1up-regulatesZNF143repressesR-2325-0.4472936Pr-3
RNASeq_MAFA_Callup-regulatesZNF143repressesR-2325-0.4472936Pr-3
SYNE1up-regulatesZNF143repressesR-2325-0.4472936Pr-3
AHNAK2down-regulatesMEF2AactivatesR-1866-0.51852837Pr-3
MACF1down-regulatesMEF2AactivatesR-1866-0.51852837Pr-3
MAGI1down-regulatesMEF2AactivatesR-1866-0.51852837Pr-3
MAXdown-regulatesMEF2AactivatesR-1866-0.51852837Pr-3
MYO10down-regulatesMEF2AactivatesR-1866-0.51852837Pr-3
PTPRDdown-regulatesMEF2AactivatesR-1866-0.51852837Pr-3
RNASeq_MAFA_Calldown-regulatesMEF2AactivatesR-1866-0.51852837Pr-3
RNASeq_MAFB_Calldown-regulatesMEF2AactivatesR-1866-0.51852837Pr-3
SYNE1down-regulatesMEF2AactivatesR-1866-0.51852837Pr-3
TACC2down-regulatesMEF2AactivatesR-1866-0.51852837Pr-3
del13up-regulatesMEF2AactivatesR-1866-0.51852837Pr-3
AHNAK2down-regulatesRREB1activatesR-2285-0.53875820Pr-3
CMYA5down-regulatesRREB1activatesR-2285-0.53875820Pr-3
MACF1down-regulatesRREB1activatesR-2285-0.53875820Pr-3
RNASeq_MAFB_Calldown-regulatesRREB1activatesR-2285-0.53875820Pr-3
SYNE1down-regulatesRREB1activatesR-2285-0.53875820Pr-3
TACC2down-regulatesRREB1activatesR-2285-0.53875820Pr-3
AHNAK2down-regulatesFOXO1activatesR-1417-0.53950211Pr-3
MACF1down-regulatesFOXO1activatesR-1417-0.53950211Pr-3
NEBdown-regulatesFOXO1activatesR-1417-0.53950211Pr-3
PTPRDdown-regulatesFOXO1activatesR-1417-0.53950211Pr-3
t(11;14)up-regulatesFOXO1activatesR-1417-0.53950211Pr-3
TACC2down-regulatesFOXO1activatesR-1417-0.53950211Pr-3
t(14;16)_cytogeneticdown-regulatesFOXO1activatesR-1417-0.53950211Pr-3
AHNAK2down-regulatesSPDEFactivatesR-1960-0.54868416Pr-3
MAGI1down-regulatesSPDEFactivatesR-1960-0.54868416Pr-3
PTPRDdown-regulatesSPDEFactivatesR-1960-0.54868416Pr-3
RNASeq_MAFB_Calldown-regulatesSPDEFactivatesR-1960-0.54868416Pr-3
del17pdown-regulatesSPDEFactivatesR-1960-0.54868416Pr-3
CMYA5down-regulatesHMBOX1activatesR-2379-0.5509569Pr-3
IRF4up-regulatesHMBOX1activatesR-2379-0.5509569Pr-3
MACF1down-regulatesHMBOX1activatesR-2379-0.5509569Pr-3
PCDH10down-regulatesHMBOX1activatesR-2379-0.5509569Pr-3
t(11;14)up-regulatesHMBOX1activatesR-2379-0.5509569Pr-3
t(11;14)_cytogeneticup-regulatesHMBOX1activatesR-2379-0.5509569Pr-3
ABCA13down-regulatesPOU2F1activatesR-71-0.5875738Pr-3
AHNAK2down-regulatesPOU2F1activatesR-71-0.5875738Pr-3
CMYA5down-regulatesPOU2F1activatesR-71-0.5875738Pr-3
DNAH5down-regulatesPOU2F1activatesR-71-0.5875738Pr-3
MACF1down-regulatesPOU2F1activatesR-71-0.5875738Pr-3
MAGI1down-regulatesPOU2F1activatesR-71-0.5875738Pr-3
MYO10down-regulatesPOU2F1activatesR-71-0.5875738Pr-3
NEBdown-regulatesPOU2F1activatesR-71-0.5875738Pr-3
PTPRDdown-regulatesPOU2F1activatesR-71-0.5875738Pr-3
t(11;14)up-regulatesPOU2F1activatesR-71-0.5875738Pr-3
TACC2down-regulatesPOU2F1activatesR-71-0.5875738Pr-3
del13up-regulatesPOU2F1activatesR-71-0.5875738Pr-3
del17down-regulatesPOU2F1activatesR-71-0.5875738Pr-3
del17pdown-regulatesPOU2F1activatesR-71-0.5875738Pr-3
t(11;14)_cytogeneticup-regulatesPOU2F1activatesR-71-0.5875738Pr-3
t(11;14)up-regulatesMAFGactivatesR-14970.6066986Pr-3
t(4;14)up-regulatesMAFGactivatesR-14970.6066986Pr-3
del13up-regulatesMAFGactivatesR-14970.6066986Pr-3
t(11;14)_cytogeneticup-regulatesMAFGactivatesR-14970.6066986Pr-3
t(4;14)_cytogeneticup-regulatesMAFGactivatesR-14970.6066986Pr-3
IRF4down-regulatesPLAG1repressesR-1520-0.62154213Pr-3
t(11;14)down-regulatesPLAG1repressesR-1520-0.62154213Pr-3
t(11;14)_cytogeneticdown-regulatesPLAG1repressesR-1520-0.62154213Pr-3
PTPRDup-regulatesTP53repressesR-377-0.6374517Pr-3
t(11;14)down-regulatesTP53repressesR-377-0.6374517Pr-3
RNASeq_FGFR3_Calldown-regulatesTP53repressesR-377-0.6374517Pr-3
t(4;14)down-regulatesTP53repressesR-377-0.6374517Pr-3
SYNE1up-regulatesTP53repressesR-377-0.6374517Pr-3
del13down-regulatesTP53repressesR-377-0.6374517Pr-3
BRAFup-regulatesHSF2activatesR-31670.6451526Pr-3
KRASup-regulatesHSF2activatesR-31670.6451526Pr-3
MYO10down-regulatesHSF2activatesR-31670.6451526Pr-3
NEBdown-regulatesHSF2activatesR-31670.6451526Pr-3
PTPRDdown-regulatesHSF2activatesR-31670.6451526Pr-3
t(11;14)up-regulatesHSF2activatesR-31670.6451526Pr-3
RNASeq_FGFR3_Callup-regulatesHSF2activatesR-31670.6451526Pr-3
RNASeq_MAFA_Calldown-regulatesHSF2activatesR-31670.6451526Pr-3
RNASeq_MAFB_Calldown-regulatesHSF2activatesR-31670.6451526Pr-3
t(11;14)_cytogeneticup-regulatesHSF2activatesR-31670.6451526Pr-3
t(14;16)_cytogeneticdown-regulatesHSF2activatesR-31670.6451526Pr-3
RNASeq_MAFA_Callup-regulatesTFCP2repressesR-1699-0.73478210Pr-3
RNASeq_MAFB_Callup-regulatesTFCP2repressesR-1699-0.73478210Pr-3
del13up-regulatesSPIBactivatesR-663-0.74429422Pr-3
DNAH5down-regulatesENSG00000179348activatesR-1069-0.7943396Pr-3
NEBdown-regulatesENSG00000179348activatesR-1069-0.7943396Pr-3
del17down-regulatesENSG00000179348activatesR-1069-0.7943396Pr-3
t(14;16)_cytogeneticdown-regulatesENSG00000179348activatesR-1069-0.7943396Pr-3
DNAH5down-regulatesIRX3activatesR-22280.8028218Pr-3
NEBdown-regulatesIRX3activatesR-22280.8028218Pr-3
RNASeq_MAFA_Calldown-regulatesIRX3activatesR-22280.8028218Pr-3
SYNE1down-regulatesIRX3activatesR-22280.8028218Pr-3
t(14;16)_cytogeneticdown-regulatesIRX3activatesR-22280.8028218Pr-3
DNAH5down-regulatesIRX3activatesR-2232-1.013676Pr-3
NEBdown-regulatesIRX3activatesR-2232-1.013676Pr-3
RNASeq_MAFA_Calldown-regulatesIRX3activatesR-2232-1.013676Pr-3
del17down-regulatesIRX3activatesR-2232-1.013676Pr-3
t(14;16)_cytogeneticdown-regulatesIRX3activatesR-2232-1.013676Pr-3
DSTdown-regulatesPBX1activatesR-21121.035947Pr-3
FGFR3up-regulatesPBX1activatesR-21121.035947Pr-3
PTPRDdown-regulatesPBX1activatesR-21121.035947Pr-3
RNASeq_FGFR3_Callup-regulatesPBX1activatesR-21121.035947Pr-3
RNASeq_MAFA_Calldown-regulatesPBX1activatesR-21121.035947Pr-3
MYCdown-regulatesPBX1activatesR-21121.035947Pr-3
t(4;14)up-regulatesPBX1activatesR-21121.035947Pr-3
SDK1down-regulatesPBX1activatesR-21121.035947Pr-3
del13up-regulatesPBX1activatesR-21121.035947Pr-3
AHNAK2down-regulatesFOXP1activatesR-3141-1.1263510Pr-3
t(11;14)up-regulatesFOXP1activatesR-3141-1.1263510Pr-3
del13up-regulatesFOXP1activatesR-3141-1.1263510Pr-3
t(11;14)_cytogeneticup-regulatesFOXP1activatesR-3141-1.1263510Pr-3
CMYA5up-regulatesHMGA1repressesR-836-1.211516Pr-3
FAM46Cup-regulatesHMGA1repressesR-836-1.211516Pr-3
IRF4down-regulatesHMGA1repressesR-836-1.211516Pr-3
MUC16up-regulatesHMGA1repressesR-836-1.211516Pr-3
NEBup-regulatesHMGA1repressesR-836-1.211516Pr-3
PRKD2down-regulatesHMGA1repressesR-836-1.211516Pr-3
t(11;14)down-regulatesHMGA1repressesR-836-1.211516Pr-3
RNASeq_FGFR3_Calldown-regulatesHMGA1repressesR-836-1.211516Pr-3
MYCup-regulatesHMGA1repressesR-836-1.211516Pr-3
t(4;14)down-regulatesHMGA1repressesR-836-1.211516Pr-3
t(11;14)_cytogeneticdown-regulatesHMGA1repressesR-836-1.211516Pr-3
t(4;14)_cytogeneticdown-regulatesHMGA1repressesR-836-1.211516Pr-3
AHNAK2down-regulatesERFactivatesR-333-1.223788Pr-3
KALRNdown-regulatesERFactivatesR-333-1.223788Pr-3
MACF1down-regulatesERFactivatesR-333-1.223788Pr-3
MAXdown-regulatesERFactivatesR-333-1.223788Pr-3
MYO10down-regulatesERFactivatesR-333-1.223788Pr-3
RNASeq_MAFA_Calldown-regulatesERFactivatesR-333-1.223788Pr-3
SYNE1down-regulatesERFactivatesR-333-1.223788Pr-3
TACC2down-regulatesERFactivatesR-333-1.223788Pr-3
del13up-regulatesERFactivatesR-333-1.223788Pr-3
t(14;16)_cytogeneticdown-regulatesERFactivatesR-333-1.223788Pr-3
CMYA5up-regulatesHMGA1repressesR-827-1.239168Pr-3
DIS3down-regulatesHMGA1repressesR-827-1.239168Pr-3
IRF4down-regulatesHMGA1repressesR-827-1.239168Pr-3
NEBup-regulatesHMGA1repressesR-827-1.239168Pr-3
t(11;14)down-regulatesHMGA1repressesR-827-1.239168Pr-3
MYCup-regulatesHMGA1repressesR-827-1.239168Pr-3
del13down-regulatesHMGA1repressesR-827-1.239168Pr-3
t(11;14)_cytogeneticdown-regulatesHMGA1repressesR-827-1.239168Pr-3
AHNAK2down-regulatesIRF1activatesR-1941.2604117Pr-3
FGFR3up-regulatesIRF1activatesR-1941.2604117Pr-3
KRASup-regulatesIRF1activatesR-1941.2604117Pr-3
NRASup-regulatesIRF1activatesR-1941.2604117Pr-3
t(11;14)up-regulatesIRF1activatesR-1941.2604117Pr-3
RNASeq_FGFR3_Callup-regulatesIRF1activatesR-1941.2604117Pr-3
t(11;14)_cytogeneticup-regulatesIRF1activatesR-1941.2604117Pr-3
t(11;14)down-regulatesDBPrepressesR-2955-1.45137Pr-3
RNASeq_FGFR3_Callup-regulatesDBPrepressesR-2955-1.45137Pr-3
t(4;14)up-regulatesDBPrepressesR-2955-1.45137Pr-3
ANK2up-regulatesZNF143repressesR-2322-1.590547Pr-3
MACF1up-regulatesZNF143repressesR-2322-1.590547Pr-3
RNASeq_MAFA_Callup-regulatesZNF143repressesR-2322-1.590547Pr-3
MYCup-regulatesZNF143repressesR-2322-1.590547Pr-3
t(14;16)_cytogeneticup-regulatesZNF143repressesR-2322-1.590547Pr-3
AHNAK2down-regulatesIRF9activatesR-11551.695139Pr-3
DIS3up-regulatesIRF9activatesR-11551.695139Pr-3
FGFR3up-regulatesIRF9activatesR-11551.695139Pr-3
FLGdown-regulatesIRF9activatesR-11551.695139Pr-3
RNASeq_FGFR3_Callup-regulatesIRF9activatesR-11551.695139Pr-3
TRAF3down-regulatesIRF9activatesR-11551.695139Pr-3
AHNAK2down-regulatesNFKB1activatesR-1588-1.788227Pr-3
MACF1down-regulatesNFKB1activatesR-1588-1.788227Pr-3
MYO10down-regulatesNFKB1activatesR-1588-1.788227Pr-3
CMYA5down-regulatesZBTB16activatesR-5861.8127710Pr-3
DNAH5down-regulatesZBTB16activatesR-5861.8127710Pr-3
FGFR3up-regulatesZBTB16activatesR-5861.8127710Pr-3
IRF4up-regulatesZBTB16activatesR-5861.8127710Pr-3
MYO10down-regulatesZBTB16activatesR-5861.8127710Pr-3
NEBdown-regulatesZBTB16activatesR-5861.8127710Pr-3
t(11;14)up-regulatesZBTB16activatesR-5861.8127710Pr-3
t(11;14)_cytogeneticup-regulatesZBTB16activatesR-5861.8127710Pr-3
NEBdown-regulatesZNF410activatesR-19391.97168Pr-3
del13up-regulatesZNF410activatesR-19391.97168Pr-3
CYLDdown-regulatesTEAD1repressesR-1215-2.02239Pr-3
FGFR3up-regulatesTEAD1repressesR-1215-2.02239Pr-3
t(11;14)down-regulatesTEAD1repressesR-1215-2.02239Pr-3
RNASeq_FGFR3_Callup-regulatesTEAD1repressesR-1215-2.02239Pr-3
t(4;14)up-regulatesTEAD1repressesR-1215-2.02239Pr-3
t(11;14)_cytogeneticdown-regulatesTEAD1repressesR-1215-2.02239Pr-3
t(4;14)_cytogeneticup-regulatesTEAD1repressesR-1215-2.02239Pr-3
AHNAK2down-regulatesETV3activatesR-2532-2.08198Pr-3
RNASeq_MAFA_Calldown-regulatesETV3activatesR-2532-2.08198Pr-3
SYNE1down-regulatesETV3activatesR-2532-2.08198Pr-3
TACC2down-regulatesETV3activatesR-2532-2.08198Pr-3
del13up-regulatesETV3activatesR-2532-2.08198Pr-3
IRF4up-regulatesRARAactivatesR-167-2.366819Pr-3
MAGI1down-regulatesRARAactivatesR-167-2.366819Pr-3
MAXdown-regulatesRARAactivatesR-167-2.366819Pr-3
t(11;14)up-regulatesRARAactivatesR-167-2.366819Pr-3
TACC2down-regulatesRARAactivatesR-167-2.366819Pr-3
TP53down-regulatesRARAactivatesR-167-2.366819Pr-3
t(11;14)_cytogeneticup-regulatesRARAactivatesR-167-2.366819Pr-3
RNASeq_MAFA_Callup-regulatesZNF691repressesR-3010-2.545717Pr-3
AHNAK2down-regulatesNFKB1activatesR-1589-3.219357Pr-3
DIS3down-regulatesNFKB1activatesR-1589-3.219357Pr-3
FAT3down-regulatesNFKB1activatesR-1589-3.219357Pr-3
MAXdown-regulatesNFKB1activatesR-1589-3.219357Pr-3
RNASeq_FGFR3_Calldown-regulatesNFKB1activatesR-1589-3.219357Pr-3
t(4;14)down-regulatesNFKB1activatesR-1589-3.219357Pr-3
TACC2down-regulatesNFKB1activatesR-1589-3.219357Pr-3
t(4;14)_cytogeneticdown-regulatesNFKB1activatesR-1589-3.219357Pr-3
CMYA5up-regulatesHMGA1repressesR-829-4.151177Pr-3
NEBup-regulatesHMGA1repressesR-829-4.151177Pr-3
t(11;14)down-regulatesHMGA1repressesR-829-4.151177Pr-3
RNASeq_CCND3_Calldown-regulatesHMGA1repressesR-829-4.151177Pr-3
MYCup-regulatesHMGA1repressesR-829-4.151177Pr-3
t(11;14)_cytogeneticdown-regulatesHMGA1repressesR-829-4.151177Pr-3

Regulons in program Pr-3

Regulon Cox Hazard Ratio # genes # causal flows
R-26190.0114715128
R-21480.0747421127
R-30540.128472106
R-2410-0.1405494
R-228-0.18548884
R-30040.19580562
R-2876-0.2903353515
R-1907-0.317014812
R-1191-0.320198329
R-24900.324798
R-2769-0.336939332
R-1000-0.380145335
R-3121-0.417258357
R-1275-0.421961613
R-22-0.436928105
R-2325-0.44729363
R-1866-0.5185283711
R-2285-0.538758206
R-1417-0.539502117
R-1960-0.548684165
R-2379-0.55095696
R-71-0.587573815
R-14970.60669865
R-1520-0.621542133
R-377-0.63745176
R-31670.645152611
R-1699-0.734782102
R-663-0.744294221
R-1069-0.79433964
R-22280.80282185
R-2232-1.0136765
R-21121.0359479
R-3141-1.12635104
R-836-1.21151612
R-333-1.22378810
R-827-1.2391688
R-1941.26041177
R-2955-1.451373
R-2322-1.5905475
R-11551.6951396
R-1588-1.7882273
R-5861.81277108
R-19391.971682
R-1215-2.022397
R-2532-2.081985
R-167-2.3668197
R-3010-2.5457171
R-1589-3.2193578
R-829-4.1511776

Program Survival Plots

Kaplan-Meier curves demonstrating the sub-stratification of clinical subtypes based upon the network activity of the most predictive individual or pair of genes as determined by the LASSO predictions