| NRF1 | down-regulates | R-2707 | -0.0919786 | Pr-117 Genes (51)LRRC25, MRPL48, CNTD1, EFCAB5, ZDHHC13, PPFIA3, TBL1XR1, IL17RA, POLR2L, KLHL28, SHARPIN, PHLDA2, IST1, SKA2, JRKL, TRMT12, WDR27, ADSSL1, SHC4, YTHDF3, ZNF267, OR2AG2, PTAR1, SLX4, PRPF40A, RABL6, ANXA4, WDR5B, MAFG, TOPORS, KCNMB2, MFAP3L, PHACTR4, TRIQK, SUPT4H1, LTC4S, DDX47, FIS1, CKLF, FAM185A, RARB, IRF4, HOXA3 Regulons (53)R-2087, R-1556, R-2707, R-342, R-2610, R-2252, R-62, R-1904, R-1388, R-1266, R-2882, R-369, R-451, R-1677, R-1495, R-1591, R-771, R-2371, R-2535, R-1846, R-945, R-500, R-986, R-2995, R-2886, R-630, R-2738, R-2991, R-1735, R-1032, R-643, R-2069, R-1485, R-2179, R-2961, R-157, R-2336, R-2142, R-2358, R-1271, R-1489, R-1734, R-2090, R-1742, R-2070, R-3168, R-2704, R-994, R-2335, R-1786, R-539, R-2068, R-1929 |
| TCF7L1 | down-regulates | R-3174 | -0.135953 | Pr-99 Genes (28)GNG7, ZBTB34, APOBEC3B, PSMG4, HSF1, PRPF39, ARL15, CERKL, MSL1, ZNF79, PLXNB2, YTHDF2, TLK1, TSEN15, CAPZA2, FCGR3A, LIME1, SMIM5, C6orf47, DENND6B, LIN52, RBMXL1, EMP2, TMEM167B, ZSCAN31, CDRT4 Regulons (31)R-3174, R-453, R-1770, R-3083, R-1212, R-648, R-2506, R-2709, R-1696, R-2314, R-2642, R-587, R-492, R-1891, R-3063, R-640, R-2162, R-3070, R-1834, R-188, R-2140, R-2317, R-1435, R-3129, R-699, R-3090, R-650, R-1007, R-2844, R-2311, R-606 |
| NFIL3 | down-regulates | R-1686 | -0.145704 | Pr-25 Genes (9)RNPEP, RUFY1, ZNF664, TRNAU1AP, CLEC4G, SRC, HLA-F, RTL5 Regulons (9)R-974, R-1686, R-160, R-709, R-2312, R-2984, R-2341, R-2802, R-3062 |
| ZBTB16 | down-regulates | R-589 | 0.185533 | Pr-125 Genes (16)RPS6KA3, GBA, HMGN4, CMTM4, TEAD1, BCAM, NIF3L1, MKL1, CR1, RING1, PVRIG, GET4, LOC102724159, PI4KA, SMIM20 Regulons (17)R-589, R-1538, R-54, R-2559, R-2953, R-223, R-1504, R-1914, R-3162, R-2359, R-1975, R-2741, R-2547, R-892, R-482, R-2476, R-1703 |
| NF1 | down-regulates | R-127 | -0.22305 | Pr-18 Genes (11)RPRM, FRAT2, SCFD2, PARPBP, ADAT2, INCA1, CASP4, DDRGK1, DDR1 Regulons (15)R-127, R-1406, R-1883, R-89, R-221, R-1440, R-604, R-2385, R-2515, R-1076, R-165, R-2899, R-2246, R-2731, R-1671 |
| POU2F1 | down-regulates | R-77 | -0.259838 | Pr-14 Genes (17)TMEM70, TUBB6, PNMA1, CASKIN2, ANXA2R, MLF1, ARID3B, SLC17A8, FZD2, PLAG1, SLC8A1, SEMA4B, NOXA1, AKR1C3, MPV17L2 Regulons (18)R-1002, R-1429, R-1659, R-894, R-77, R-1832, R-1545, R-184, R-2284, R-2223, R-2075, R-2878, R-2606, R-1398, R-2952, R-1932, R-3170, R-2014 |
| HBP1 | down-regulates | R-1832 | 0.278908 | Pr-14 Genes (17)TMEM70, TUBB6, PNMA1, CASKIN2, ANXA2R, MLF1, ARID3B, SLC17A8, FZD2, PLAG1, SLC8A1, SEMA4B, NOXA1, AKR1C3, MPV17L2 Regulons (18)R-1002, R-1429, R-1659, R-894, R-77, R-1832, R-1545, R-184, R-2284, R-2223, R-2075, R-2878, R-2606, R-1398, R-2952, R-1932, R-3170, R-2014 |
| FOXJ3 | down-regulates | R-2876 | -0.290335 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| ATF1 | up-regulates | R-564 | 0.297759 | Pr-93 Genes (9)B3GNT5, PLEC, MME, ZNF700, SND1, VEPH1, ZNF480, ZHX1-C8orf76 Regulons (9)R-1522, R-564, R-13, R-1438, R-310, R-3131, R-826, R-2725, R-2630 |
| SF1 | down-regulates | R-1907 | -0.317014 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| RARA | down-regulates | R-160 | -0.331894 | Pr-25 Genes (9)RNPEP, RUFY1, ZNF664, TRNAU1AP, CLEC4G, SRC, HLA-F, RTL5 Regulons (9)R-974, R-1686, R-160, R-709, R-2312, R-2984, R-2341, R-2802, R-3062 |
| TFEB | down-regulates | R-885 | -0.336909 | Pr-0 Genes (84)GPX2, BNIP3, METRNL, PUS1, SAMD12, CD163, SLC25A20, EFCAB13, EXOSC4, SAMD4B, CATSPERE, C14orf119, ARHGAP45, BBS12, EHMT1, SETD2, ZBTB20, RFX7, TSKU, SRPRA, SLC25A10, ASB7, UPP1, LIN9, CCR10, ZFP1, USP18, TNFAIP2, CDNF, SOCS1, METTL7A, PDE6G, SP1, P4HB, DRG1, CXorf38, MORF4L1, AIDA, WWOX, SAPCD2, PPP1CC, SPIN4, CXCR3, ZNF397, TPCN1, CMC1, GCNT1, FNBP1, RSBN1L, LOC100288637, TMPPE, ZC3H6, ZNF669, NANOS1, ALKBH2, JPT1, LIN54, HLA-DRB1, ZNF493, EPHB4, TRAPPC2B, SIAH1, ESRRG, TCF4, SERTAD1, ZNF398, ZNF257, ATG7, MPEG1, RPS4X, PNP, HMGN2, HIST2H2BF, COLQ, RPS29 Regulons (86)R-180, R-2076, R-2157, R-3164, R-3147, R-338, R-2156, R-2409, R-885, R-941, R-1192, R-556, R-3197, R-1572, R-999, R-636, R-902, R-2541, R-440, R-890, R-3175, R-767, R-1542, R-1336, R-2472, R-1698, R-2326, R-1906, R-269, R-772, R-647, R-3033, R-2100, R-2711, R-1394, R-3068, R-508, R-63, R-1916, R-1188, R-532, R-2135, R-997, R-1687, R-2951, R-1853, R-2220, R-577, R-585, R-2597, R-1021, R-3119, R-301, R-559, R-1560, R-175, R-2870, R-3015, R-66, R-595, R-3185, R-2905, R-433, R-290, R-381, R-2509, R-562, R-2798, R-2206, R-1418, R-60, R-3050, R-2073, R-611, R-2488, R-881, R-1095, R-2153, R-2553, R-2305, R-2656, R-1697, R-511, R-2185, R-1492, R-2555 |
| HMBOX1 | down-regulates | R-2382 | 0.378178 | Pr-62 Genes (12)DTX3, EGR3, NRIP1, CYP4F3, HEXIM1, RNF220, SRSF10, LCOR, TXNRD1, TPM2, SPIB Regulons (13)R-510, R-2382, R-1511, R-126, R-3008, R-2280, R-1151, R-2116, R-1563, R-2512, R-961, R-976, R-2727 |
| HINFP | down-regulates | R-2624 | -0.44835 | Pr-35 Genes (10)ZBTB7A, TMEM107, BHLHA15, GLTPD2, ZNF395, MAFB, SMIM13, AKAP2, FOX3A Regulons (20)R-2747, R-3059, R-336, R-2624, R-1948, R-14, R-277, R-2826, R-1570, R-1094, R-1244, R-2621, R-1232, R-1506, R-3019, R-493, R-1945, R-2691, R-1963, R-2244 |
| IRX3 | down-regulates | R-2223 | -0.522117 | Pr-14 Genes (17)TMEM70, TUBB6, PNMA1, CASKIN2, ANXA2R, MLF1, ARID3B, SLC17A8, FZD2, PLAG1, SLC8A1, SEMA4B, NOXA1, AKR1C3, MPV17L2 Regulons (18)R-1002, R-1429, R-1659, R-894, R-77, R-1832, R-1545, R-184, R-2284, R-2223, R-2075, R-2878, R-2606, R-1398, R-2952, R-1932, R-3170, R-2014 |
| E2F2 | up-regulates | R-2943 | -0.530398 | Pr-58 Genes (28)ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28)R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148 |
| FOXJ3 | down-regulates | R-2893 | 0.536867 | Pr-33 Genes (6)ZNF620, IMPDH2, SLC35C1, TIGIT, AP2A2, C11orf96 Regulons (6)R-1415, R-2349, R-2893, R-2147, R-1014, R-2205 |
| IKZF1 | down-regulates | R-991 | 0.573701 | Pr-124 Genes (20)MYPOP, DMAP1, PER1, C1S, DENND5A, TSPYL2, KNTC1, TMEM105, LRCH3, ZBTB6, CFAP73, LILRB4, TNFRSF18, LITAF, ZNF665, IPO7, KMT2B Regulons (20)R-1400, R-1425, R-1962, R-1828, R-991, R-1083, R-1577, R-72, R-2158, R-3069, R-2814, R-1149, R-1631, R-182, R-1340, R-3034, R-3139, R-39, R-199, R-593 |
| IRX3 | down-regulates | R-2234 | -0.576042 | Pr-88 Genes (14)GADD45GIP1, PAK2, D2HGDH, AEN, DHTKD1, KBTBD3, RPS27L, CD47, ZNF587, SFMBT2, DCLRE1A, TCTN1, MEF2B Regulons (16)R-900, R-491, R-893, R-102, R-1247, R-2627, R-2234, R-2684, R-3138, R-368, R-2620, R-104, R-1690, R-1206, R-3142, R-2660 |
| POU2F1 | down-regulates | R-71 | -0.58757 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| FOXJ3 | down-regulates | R-2881 | -0.590232 | Pr-34 Genes (6)ACSF3, PPA1, CRIP2, TMEM216, MAGI2, TOGARAM1 Regulons (6)R-3038, R-1487, R-2881, R-1430, R-1835, R-2239 |
| SMAD4 | down-regulates | R-2357 | -0.642425 | Pr-60 Genes (13)MYLPF, CXCR2, SCRIB, RNF41, PPP1R27, FAM167B, SIGIRR, NOC2L, KLHL14, SELENOH, STARD10, TNFSF12, SELENOP Regulons (16)R-12, R-2753, R-314, R-2433, R-1411, R-2357, R-2343, R-1509, R-1392, R-1657, R-2736, R-3179, R-1338, R-1887, R-354, R-1354 |
| FOXJ3 | down-regulates | R-2878 | -0.651802 | Pr-14 Genes (17)TMEM70, TUBB6, PNMA1, CASKIN2, ANXA2R, MLF1, ARID3B, SLC17A8, FZD2, PLAG1, SLC8A1, SEMA4B, NOXA1, AKR1C3, MPV17L2 Regulons (18)R-1002, R-1429, R-1659, R-894, R-77, R-1832, R-1545, R-184, R-2284, R-2223, R-2075, R-2878, R-2606, R-1398, R-2952, R-1932, R-3170, R-2014 |
| NFATC1 | down-regulates | R-2197 | 0.666306 | Pr-29 Genes (9)P2RY2, SAMD9L, TMEM187, TRAK1, ANKRD45, PTP4A2, ZNF565, C17orf51 Regulons (9)R-1401, R-1870, R-1733, R-80, R-2197, R-993, R-1308, R-2683, R-548 |
| NFATC1 | down-regulates | R-2201 | -0.687031 | Pr-120 Genes (9)ANKLE2, TMEM52, YOD1, ZNF443, CDCA2, SIVA1, PSMD13, CHAMP1 Regulons (9)R-2299, R-2503, R-2342, R-546, R-2201, R-1346, R-1651, R-792, R-2963 |
| NRF1 | down-regulates | R-2709 | -0.785764 | Pr-99 Genes (28)GNG7, ZBTB34, APOBEC3B, PSMG4, HSF1, PRPF39, ARL15, CERKL, MSL1, ZNF79, PLXNB2, YTHDF2, TLK1, TSEN15, CAPZA2, FCGR3A, LIME1, SMIM5, C6orf47, DENND6B, LIN52, RBMXL1, EMP2, TMEM167B, ZSCAN31, CDRT4 Regulons (31)R-3174, R-453, R-1770, R-3083, R-1212, R-648, R-2506, R-2709, R-1696, R-2314, R-2642, R-587, R-492, R-1891, R-3063, R-640, R-2162, R-3070, R-1834, R-188, R-2140, R-2317, R-1435, R-3129, R-699, R-3090, R-650, R-1007, R-2844, R-2311, R-606 |
| THRA | down-regulates | R-57 | 0.789789 | Pr-134 Genes (104)MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1 Regulons (119)R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272 |
| ENSG00000179348 | down-regulates | R-1069 | -0.794339 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| IRX3 | down-regulates | R-2228 | 0.802821 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| BBX | down-regulates | R-1536 | -0.809151 | Pr-10 Genes (26)ATAD5, MANEAL, RBM34, MAN2A2, AMZ2, VKORC1L1, TLE1, ANKRD36B, CXorf40B, PCNX3, ENTPD4, FITM2, GFPT1, FICD, R3HDM4, HSPA1B, TMEM231, CDKL4, RAB12, ANKRD28, ZNF844, ERCC6, BORCS8-MEF2B Regulons (27)R-1850, R-2412, R-276, R-1536, R-2572, R-755, R-607, R-2204, R-1353, R-1673, R-903, R-571, R-2217, R-2657, R-2774, R-448, R-2892, R-1205, R-757, R-1976, R-1918, R-2149, R-2491, R-2302, R-274, R-588, R-95 |
| ZBTB16 | down-regulates | R-580 | 0.838599 | Pr-134 Genes (104)MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1 Regulons (119)R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272 |
| MAFK | down-regulates | R-2814 | 0.847631 | Pr-124 Genes (20)MYPOP, DMAP1, PER1, C1S, DENND5A, TSPYL2, KNTC1, TMEM105, LRCH3, ZBTB6, CFAP73, LILRB4, TNFRSF18, LITAF, ZNF665, IPO7, KMT2B Regulons (20)R-1400, R-1425, R-1962, R-1828, R-991, R-1083, R-1577, R-72, R-2158, R-3069, R-2814, R-1149, R-1631, R-182, R-1340, R-3034, R-3139, R-39, R-199, R-593 |
| STAT4 | down-regulates | R-2659 | -0.852357 | Pr-134 Genes (104)MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1 Regulons (119)R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272 |
| ZBTB16 | down-regulates | R-578 | -0.879917 | Pr-58 Genes (28)ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28)R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148 |
| ZBTB16 | down-regulates | R-577 | -0.900835 | Pr-0 Genes (84)GPX2, BNIP3, METRNL, PUS1, SAMD12, CD163, SLC25A20, EFCAB13, EXOSC4, SAMD4B, CATSPERE, C14orf119, ARHGAP45, BBS12, EHMT1, SETD2, ZBTB20, RFX7, TSKU, SRPRA, SLC25A10, ASB7, UPP1, LIN9, CCR10, ZFP1, USP18, TNFAIP2, CDNF, SOCS1, METTL7A, PDE6G, SP1, P4HB, DRG1, CXorf38, MORF4L1, AIDA, WWOX, SAPCD2, PPP1CC, SPIN4, CXCR3, ZNF397, TPCN1, CMC1, GCNT1, FNBP1, RSBN1L, LOC100288637, TMPPE, ZC3H6, ZNF669, NANOS1, ALKBH2, JPT1, LIN54, HLA-DRB1, ZNF493, EPHB4, TRAPPC2B, SIAH1, ESRRG, TCF4, SERTAD1, ZNF398, ZNF257, ATG7, MPEG1, RPS4X, PNP, HMGN2, HIST2H2BF, COLQ, RPS29 Regulons (86)R-180, R-2076, R-2157, R-3164, R-3147, R-338, R-2156, R-2409, R-885, R-941, R-1192, R-556, R-3197, R-1572, R-999, R-636, R-902, R-2541, R-440, R-890, R-3175, R-767, R-1542, R-1336, R-2472, R-1698, R-2326, R-1906, R-269, R-772, R-647, R-3033, R-2100, R-2711, R-1394, R-3068, R-508, R-63, R-1916, R-1188, R-532, R-2135, R-997, R-1687, R-2951, R-1853, R-2220, R-577, R-585, R-2597, R-1021, R-3119, R-301, R-559, R-1560, R-175, R-2870, R-3015, R-66, R-595, R-3185, R-2905, R-433, R-290, R-381, R-2509, R-562, R-2798, R-2206, R-1418, R-60, R-3050, R-2073, R-611, R-2488, R-881, R-1095, R-2153, R-2553, R-2305, R-2656, R-1697, R-511, R-2185, R-1492, R-2555 |
| HBP1 | down-regulates | R-1835 | -0.944524 | Pr-34 Genes (6)ACSF3, PPA1, CRIP2, TMEM216, MAGI2, TOGARAM1 Regulons (6)R-3038, R-1487, R-2881, R-1430, R-1835, R-2239 |
| SMAD4 | down-regulates | R-2353 | -0.946769 | Pr-58 Genes (28)ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28)R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148 |
| NFATC1 | down-regulates | R-2205 | 0.94749 | Pr-33 Genes (6)ZNF620, IMPDH2, SLC35C1, TIGIT, AP2A2, C11orf96 Regulons (6)R-1415, R-2349, R-2893, R-2147, R-1014, R-2205 |
| FOXJ3 | down-regulates | R-2870 | -0.999227 | Pr-0 Genes (84)GPX2, BNIP3, METRNL, PUS1, SAMD12, CD163, SLC25A20, EFCAB13, EXOSC4, SAMD4B, CATSPERE, C14orf119, ARHGAP45, BBS12, EHMT1, SETD2, ZBTB20, RFX7, TSKU, SRPRA, SLC25A10, ASB7, UPP1, LIN9, CCR10, ZFP1, USP18, TNFAIP2, CDNF, SOCS1, METTL7A, PDE6G, SP1, P4HB, DRG1, CXorf38, MORF4L1, AIDA, WWOX, SAPCD2, PPP1CC, SPIN4, CXCR3, ZNF397, TPCN1, CMC1, GCNT1, FNBP1, RSBN1L, LOC100288637, TMPPE, ZC3H6, ZNF669, NANOS1, ALKBH2, JPT1, LIN54, HLA-DRB1, ZNF493, EPHB4, TRAPPC2B, SIAH1, ESRRG, TCF4, SERTAD1, ZNF398, ZNF257, ATG7, MPEG1, RPS4X, PNP, HMGN2, HIST2H2BF, COLQ, RPS29 Regulons (86)R-180, R-2076, R-2157, R-3164, R-3147, R-338, R-2156, R-2409, R-885, R-941, R-1192, R-556, R-3197, R-1572, R-999, R-636, R-902, R-2541, R-440, R-890, R-3175, R-767, R-1542, R-1336, R-2472, R-1698, R-2326, R-1906, R-269, R-772, R-647, R-3033, R-2100, R-2711, R-1394, R-3068, R-508, R-63, R-1916, R-1188, R-532, R-2135, R-997, R-1687, R-2951, R-1853, R-2220, R-577, R-585, R-2597, R-1021, R-3119, R-301, R-559, R-1560, R-175, R-2870, R-3015, R-66, R-595, R-3185, R-2905, R-433, R-290, R-381, R-2509, R-562, R-2798, R-2206, R-1418, R-60, R-3050, R-2073, R-611, R-2488, R-881, R-1095, R-2153, R-2553, R-2305, R-2656, R-1697, R-511, R-2185, R-1492, R-2555 |
| HBP1 | down-regulates | R-1838 | -1.00343 | Pr-112 Genes (5)CD19, COMMD6, MRPL21, IPP, FAM228B Regulons (10)R-161, R-1838, R-3036, R-1491, R-2275, R-835, R-676, R-1746, R-592, R-1218 |
| NFATC1 | down-regulates | R-2207 | -1.00385 | Pr-15 Genes (14)RBM33, RUFY4, SLC39A10, RPE, GLMP, MSRB1, BMPR2, SIPA1, VDAC1, EIF6, STON1, PRKDC Regulons (22)R-2088, R-2040, R-2207, R-282, R-2251, R-2946, R-1593, R-2737, R-1470, R-1848, R-1263, R-297, R-989, R-36, R-1782, R-1427, R-2049, R-2191, R-2288, R-1104, R-149, R-2959 |
| POU2F1 | down-regulates | R-66 | -1.00411 | Pr-0 Genes (84)GPX2, BNIP3, METRNL, PUS1, SAMD12, CD163, SLC25A20, EFCAB13, EXOSC4, SAMD4B, CATSPERE, C14orf119, ARHGAP45, BBS12, EHMT1, SETD2, ZBTB20, RFX7, TSKU, SRPRA, SLC25A10, ASB7, UPP1, LIN9, CCR10, ZFP1, USP18, TNFAIP2, CDNF, SOCS1, METTL7A, PDE6G, SP1, P4HB, DRG1, CXorf38, MORF4L1, AIDA, WWOX, SAPCD2, PPP1CC, SPIN4, CXCR3, ZNF397, TPCN1, CMC1, GCNT1, FNBP1, RSBN1L, LOC100288637, TMPPE, ZC3H6, ZNF669, NANOS1, ALKBH2, JPT1, LIN54, HLA-DRB1, ZNF493, EPHB4, TRAPPC2B, SIAH1, ESRRG, TCF4, SERTAD1, ZNF398, ZNF257, ATG7, MPEG1, RPS4X, PNP, HMGN2, HIST2H2BF, COLQ, RPS29 Regulons (86)R-180, R-2076, R-2157, R-3164, R-3147, R-338, R-2156, R-2409, R-885, R-941, R-1192, R-556, R-3197, R-1572, R-999, R-636, R-902, R-2541, R-440, R-890, R-3175, R-767, R-1542, R-1336, R-2472, R-1698, R-2326, R-1906, R-269, R-772, R-647, R-3033, R-2100, R-2711, R-1394, R-3068, R-508, R-63, R-1916, R-1188, R-532, R-2135, R-997, R-1687, R-2951, R-1853, R-2220, R-577, R-585, R-2597, R-1021, R-3119, R-301, R-559, R-1560, R-175, R-2870, R-3015, R-66, R-595, R-3185, R-2905, R-433, R-290, R-381, R-2509, R-562, R-2798, R-2206, R-1418, R-60, R-3050, R-2073, R-611, R-2488, R-881, R-1095, R-2153, R-2553, R-2305, R-2656, R-1697, R-511, R-2185, R-1492, R-2555 |
| IRX3 | down-regulates | R-2232 | -1.01367 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| RFX1 | down-regulates | R-2572 | -1.03711 | Pr-10 Genes (26)ATAD5, MANEAL, RBM34, MAN2A2, AMZ2, VKORC1L1, TLE1, ANKRD36B, CXorf40B, PCNX3, ENTPD4, FITM2, GFPT1, FICD, R3HDM4, HSPA1B, TMEM231, CDKL4, RAB12, ANKRD28, ZNF844, ERCC6, BORCS8-MEF2B Regulons (27)R-1850, R-2412, R-276, R-1536, R-2572, R-755, R-607, R-2204, R-1353, R-1673, R-903, R-571, R-2217, R-2657, R-2774, R-448, R-2892, R-1205, R-757, R-1976, R-1918, R-2149, R-2491, R-2302, R-274, R-588, R-95 |
| CREB1 | down-regulates | R-273 | -1.05492 | Pr-9 Genes (30)SLC26A11, DDX60L, CA13, RAB11B, SOWAHB, GNG2, UBE2H, KIF24, PLSCR1, ANKDD1B, EVL, TECPR2, NF1, SIGLEC15, PCBP2, LOC105369247, ZNF624, S100A10, PLN, CALM1, TTC37, ANKRD13B, ZNF652, RCSD1, ARHGAP11A, DCAF12, SMC5, C10orf128 Regulons (30)R-1534, R-1278, R-2296, R-1107, R-159, R-52, R-1264, R-4, R-1953, R-1718, R-273, R-2166, R-2728, R-195, R-1344, R-503, R-2613, R-1878, R-541, R-2806, R-1583, R-2340, R-2143, R-2480, R-1408, R-2570, R-2061, R-2654, R-1476, R-442 |
| ELK3 | down-regulates | R-2845 | 1.08229 | Pr-136 Genes (30)TPRN, WRB, IFITM2, LILRA5, C2orf88, RILPL1, TUBB4B, KAZN, FAM72D, GAL3ST4, SREBF2, CENPW, SARNP, MFSD2B, FGFR1OP, GPC2, SRA1, LBH, FAM200A, OST4, KIFC1, APOPT1, S1PR2, FOXJ1, TGIF1 Regulons (34)R-1265, R-2164, R-193, R-3073, R-638, R-2640, R-2531, R-2238, R-331, R-0, R-339, R-2845, R-1902, R-2701, R-1452, R-702, R-695, R-2566, R-1421, R-2803, R-1827, R-2404, R-2705, R-1453, R-2266, R-87, R-834, R-779, R-1471, R-335, R-1571, R-970, R-2751, R-1629 |
| POU2F1 | down-regulates | R-82 | 1.08267 | Pr-134 Genes (104)MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1 Regulons (119)R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272 |
| ATF1 | up-regulates | R-562 | -1.1286 | Pr-0 Genes (84)GPX2, BNIP3, METRNL, PUS1, SAMD12, CD163, SLC25A20, EFCAB13, EXOSC4, SAMD4B, CATSPERE, C14orf119, ARHGAP45, BBS12, EHMT1, SETD2, ZBTB20, RFX7, TSKU, SRPRA, SLC25A10, ASB7, UPP1, LIN9, CCR10, ZFP1, USP18, TNFAIP2, CDNF, SOCS1, METTL7A, PDE6G, SP1, P4HB, DRG1, CXorf38, MORF4L1, AIDA, WWOX, SAPCD2, PPP1CC, SPIN4, CXCR3, ZNF397, TPCN1, CMC1, GCNT1, FNBP1, RSBN1L, LOC100288637, TMPPE, ZC3H6, ZNF669, NANOS1, ALKBH2, JPT1, LIN54, HLA-DRB1, ZNF493, EPHB4, TRAPPC2B, SIAH1, ESRRG, TCF4, SERTAD1, ZNF398, ZNF257, ATG7, MPEG1, RPS4X, PNP, HMGN2, HIST2H2BF, COLQ, RPS29 Regulons (86)R-180, R-2076, R-2157, R-3164, R-3147, R-338, R-2156, R-2409, R-885, R-941, R-1192, R-556, R-3197, R-1572, R-999, R-636, R-902, R-2541, R-440, R-890, R-3175, R-767, R-1542, R-1336, R-2472, R-1698, R-2326, R-1906, R-269, R-772, R-647, R-3033, R-2100, R-2711, R-1394, R-3068, R-508, R-63, R-1916, R-1188, R-532, R-2135, R-997, R-1687, R-2951, R-1853, R-2220, R-577, R-585, R-2597, R-1021, R-3119, R-301, R-559, R-1560, R-175, R-2870, R-3015, R-66, R-595, R-3185, R-2905, R-433, R-290, R-381, R-2509, R-562, R-2798, R-2206, R-1418, R-60, R-3050, R-2073, R-611, R-2488, R-881, R-1095, R-2153, R-2553, R-2305, R-2656, R-1697, R-511, R-2185, R-1492, R-2555 |
| POU2F1 | down-regulates | R-67 | -1.13734 | Pr-58 Genes (28)ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28)R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148 |
| FOXJ3 | down-regulates | R-2871 | -1.14551 | Pr-58 Genes (28)ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28)R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148 |
| NFATC1 | down-regulates | R-2204 | -1.15799 | Pr-10 Genes (26)ATAD5, MANEAL, RBM34, MAN2A2, AMZ2, VKORC1L1, TLE1, ANKRD36B, CXorf40B, PCNX3, ENTPD4, FITM2, GFPT1, FICD, R3HDM4, HSPA1B, TMEM231, CDKL4, RAB12, ANKRD28, ZNF844, ERCC6, BORCS8-MEF2B Regulons (27)R-1850, R-2412, R-276, R-1536, R-2572, R-755, R-607, R-2204, R-1353, R-1673, R-903, R-571, R-2217, R-2657, R-2774, R-448, R-2892, R-1205, R-757, R-1976, R-1918, R-2149, R-2491, R-2302, R-274, R-588, R-95 |
| RFX3 | down-regulates | R-1673 | -1.17273 | Pr-10 Genes (26)ATAD5, MANEAL, RBM34, MAN2A2, AMZ2, VKORC1L1, TLE1, ANKRD36B, CXorf40B, PCNX3, ENTPD4, FITM2, GFPT1, FICD, R3HDM4, HSPA1B, TMEM231, CDKL4, RAB12, ANKRD28, ZNF844, ERCC6, BORCS8-MEF2B Regulons (27)R-1850, R-2412, R-276, R-1536, R-2572, R-755, R-607, R-2204, R-1353, R-1673, R-903, R-571, R-2217, R-2657, R-2774, R-448, R-2892, R-1205, R-757, R-1976, R-1918, R-2149, R-2491, R-2302, R-274, R-588, R-95 |
| ATF1 | up-regulates | R-571 | -1.19606 | Pr-10 Genes (26)ATAD5, MANEAL, RBM34, MAN2A2, AMZ2, VKORC1L1, TLE1, ANKRD36B, CXorf40B, PCNX3, ENTPD4, FITM2, GFPT1, FICD, R3HDM4, HSPA1B, TMEM231, CDKL4, RAB12, ANKRD28, ZNF844, ERCC6, BORCS8-MEF2B Regulons (27)R-1850, R-2412, R-276, R-1536, R-2572, R-755, R-607, R-2204, R-1353, R-1673, R-903, R-571, R-2217, R-2657, R-2774, R-448, R-2892, R-1205, R-757, R-1976, R-1918, R-2149, R-2491, R-2302, R-274, R-588, R-95 |
| STAT4 | down-regulates | R-2657 | -1.22095 | Pr-10 Genes (26)ATAD5, MANEAL, RBM34, MAN2A2, AMZ2, VKORC1L1, TLE1, ANKRD36B, CXorf40B, PCNX3, ENTPD4, FITM2, GFPT1, FICD, R3HDM4, HSPA1B, TMEM231, CDKL4, RAB12, ANKRD28, ZNF844, ERCC6, BORCS8-MEF2B Regulons (27)R-1850, R-2412, R-276, R-1536, R-2572, R-755, R-607, R-2204, R-1353, R-1673, R-903, R-571, R-2217, R-2657, R-2774, R-448, R-2892, R-1205, R-757, R-1976, R-1918, R-2149, R-2491, R-2302, R-274, R-588, R-95 |
| RARA | down-regulates | R-164 | 1.24046 | Pr-119 |
| RFX3 | down-regulates | R-1672 | -1.25932 | Pr-140 |
| RARA | down-regulates | R-148 | 1.3622 | Pr-5 Genes (32)ZNF25, POLD4, CLK2, EPS8L2, PIDD1, JUN, AGTRAP, C2orf69, GRINA, PTPN11, PITPNB, DNAH14, C15orf41, KIF18B, DUSP28, CFAP126, ZFP62, MYO5A, FAM114A1, FAM118B, PIM3, ZNF627, TEX45, ITPRIPL1, MRPL53, TECPR1, RNPS1, CFAP44, ZNF726, EML6, LOC441155 Regulons (33)R-362, R-1924, R-1337, R-92, R-1207, R-3137, R-2527, R-2775, R-2562, R-1927, R-2749, R-2109, R-1198, R-1854, R-275, R-2883, R-3016, R-286, R-1350, R-2038, R-148, R-42, R-3198, R-2569, R-2282, R-581, R-590, R-2346, R-2265, R-2473, R-2377, R-2110, R-1385 |
| FOXJ3 | down-regulates | R-2892 | -1.46097 | Pr-10 Genes (26)ATAD5, MANEAL, RBM34, MAN2A2, AMZ2, VKORC1L1, TLE1, ANKRD36B, CXorf40B, PCNX3, ENTPD4, FITM2, GFPT1, FICD, R3HDM4, HSPA1B, TMEM231, CDKL4, RAB12, ANKRD28, ZNF844, ERCC6, BORCS8-MEF2B Regulons (27)R-1850, R-2412, R-276, R-1536, R-2572, R-755, R-607, R-2204, R-1353, R-1673, R-903, R-571, R-2217, R-2657, R-2774, R-448, R-2892, R-1205, R-757, R-1976, R-1918, R-2149, R-2491, R-2302, R-274, R-588, R-95 |
| CREB1 | down-regulates | R-277 | -1.54447 | Pr-35 Genes (10)ZBTB7A, TMEM107, BHLHA15, GLTPD2, ZNF395, MAFB, SMIM13, AKAP2, FOX3A Regulons (20)R-2747, R-3059, R-336, R-2624, R-1948, R-14, R-277, R-2826, R-1570, R-1094, R-1244, R-2621, R-1232, R-1506, R-3019, R-493, R-1945, R-2691, R-1963, R-2244 |
| ZBTB16 | down-regulates | R-581 | -1.64909 | Pr-5 Genes (32)ZNF25, POLD4, CLK2, EPS8L2, PIDD1, JUN, AGTRAP, C2orf69, GRINA, PTPN11, PITPNB, DNAH14, C15orf41, KIF18B, DUSP28, CFAP126, ZFP62, MYO5A, FAM114A1, FAM118B, PIM3, ZNF627, TEX45, ITPRIPL1, MRPL53, TECPR1, RNPS1, CFAP44, ZNF726, EML6, LOC441155 Regulons (33)R-362, R-1924, R-1337, R-92, R-1207, R-3137, R-2527, R-2775, R-2562, R-1927, R-2749, R-2109, R-1198, R-1854, R-275, R-2883, R-3016, R-286, R-1350, R-2038, R-148, R-42, R-3198, R-2569, R-2282, R-581, R-590, R-2346, R-2265, R-2473, R-2377, R-2110, R-1385 |
| RFX1 | down-regulates | R-2566 | 1.66776 | Pr-136 Genes (30)TPRN, WRB, IFITM2, LILRA5, C2orf88, RILPL1, TUBB4B, KAZN, FAM72D, GAL3ST4, SREBF2, CENPW, SARNP, MFSD2B, FGFR1OP, GPC2, SRA1, LBH, FAM200A, OST4, KIFC1, APOPT1, S1PR2, FOXJ1, TGIF1 Regulons (34)R-1265, R-2164, R-193, R-3073, R-638, R-2640, R-2531, R-2238, R-331, R-0, R-339, R-2845, R-1902, R-2701, R-1452, R-702, R-695, R-2566, R-1421, R-2803, R-1827, R-2404, R-2705, R-1453, R-2266, R-87, R-834, R-779, R-1471, R-335, R-1571, R-970, R-2751, R-1629 |
| STAT4 | down-regulates | R-2656 | -1.67476 | Pr-0 Genes (84)GPX2, BNIP3, METRNL, PUS1, SAMD12, CD163, SLC25A20, EFCAB13, EXOSC4, SAMD4B, CATSPERE, C14orf119, ARHGAP45, BBS12, EHMT1, SETD2, ZBTB20, RFX7, TSKU, SRPRA, SLC25A10, ASB7, UPP1, LIN9, CCR10, ZFP1, USP18, TNFAIP2, CDNF, SOCS1, METTL7A, PDE6G, SP1, P4HB, DRG1, CXorf38, MORF4L1, AIDA, WWOX, SAPCD2, PPP1CC, SPIN4, CXCR3, ZNF397, TPCN1, CMC1, GCNT1, FNBP1, RSBN1L, LOC100288637, TMPPE, ZC3H6, ZNF669, NANOS1, ALKBH2, JPT1, LIN54, HLA-DRB1, ZNF493, EPHB4, TRAPPC2B, SIAH1, ESRRG, TCF4, SERTAD1, ZNF398, ZNF257, ATG7, MPEG1, RPS4X, PNP, HMGN2, HIST2H2BF, COLQ, RPS29 Regulons (86)R-180, R-2076, R-2157, R-3164, R-3147, R-338, R-2156, R-2409, R-885, R-941, R-1192, R-556, R-3197, R-1572, R-999, R-636, R-902, R-2541, R-440, R-890, R-3175, R-767, R-1542, R-1336, R-2472, R-1698, R-2326, R-1906, R-269, R-772, R-647, R-3033, R-2100, R-2711, R-1394, R-3068, R-508, R-63, R-1916, R-1188, R-532, R-2135, R-997, R-1687, R-2951, R-1853, R-2220, R-577, R-585, R-2597, R-1021, R-3119, R-301, R-559, R-1560, R-175, R-2870, R-3015, R-66, R-595, R-3185, R-2905, R-433, R-290, R-381, R-2509, R-562, R-2798, R-2206, R-1418, R-60, R-3050, R-2073, R-611, R-2488, R-881, R-1095, R-2153, R-2553, R-2305, R-2656, R-1697, R-511, R-2185, R-1492, R-2555 |
| RARA | down-regulates | R-156 | 1.71471 | Pr-16 Genes (20)NR2C2, LOC653513, C11orf54, ZNRF3, NSMCE3, LRRC70, TAF9B, B3GLCT, ZNF775, PPTC7, TRIM33, SIPA1L1, ZNF460, ZNF790, ZKSCAN8, CEP290, CIPC, GIMAP1, LILRA6, CHMP4A Regulons (20)R-383, R-191, R-50, R-872, R-1431, R-1919, R-1532, R-1546, R-2884, R-84, R-2290, R-666, R-1935, R-3128, R-1871, R-2949, R-2227, R-156, R-1279, R-2522 |
| ZBTB4 | down-regulates | R-2090 | 1.72041 | Pr-117 Genes (51)LRRC25, MRPL48, CNTD1, EFCAB5, ZDHHC13, PPFIA3, TBL1XR1, IL17RA, POLR2L, KLHL28, SHARPIN, PHLDA2, IST1, SKA2, JRKL, TRMT12, WDR27, ADSSL1, SHC4, YTHDF3, ZNF267, OR2AG2, PTAR1, SLX4, PRPF40A, RABL6, ANXA4, WDR5B, MAFG, TOPORS, KCNMB2, MFAP3L, PHACTR4, TRIQK, SUPT4H1, LTC4S, DDX47, FIS1, CKLF, FAM185A, RARB, IRF4, HOXA3 Regulons (53)R-2087, R-1556, R-2707, R-342, R-2610, R-2252, R-62, R-1904, R-1388, R-1266, R-2882, R-369, R-451, R-1677, R-1495, R-1591, R-771, R-2371, R-2535, R-1846, R-945, R-500, R-986, R-2995, R-2886, R-630, R-2738, R-2991, R-1735, R-1032, R-643, R-2069, R-1485, R-2179, R-2961, R-157, R-2336, R-2142, R-2358, R-1271, R-1489, R-1734, R-2090, R-1742, R-2070, R-3168, R-2704, R-994, R-2335, R-1786, R-539, R-2068, R-1929 |
| MAFK | down-regulates | R-2803 | -1.72936 | Pr-136 Genes (30)TPRN, WRB, IFITM2, LILRA5, C2orf88, RILPL1, TUBB4B, KAZN, FAM72D, GAL3ST4, SREBF2, CENPW, SARNP, MFSD2B, FGFR1OP, GPC2, SRA1, LBH, FAM200A, OST4, KIFC1, APOPT1, S1PR2, FOXJ1, TGIF1 Regulons (34)R-1265, R-2164, R-193, R-3073, R-638, R-2640, R-2531, R-2238, R-331, R-0, R-339, R-2845, R-1902, R-2701, R-1452, R-702, R-695, R-2566, R-1421, R-2803, R-1827, R-2404, R-2705, R-1453, R-2266, R-87, R-834, R-779, R-1471, R-335, R-1571, R-970, R-2751, R-1629 |
| HBP1 | down-regulates | R-1827 | 1.73978 | Pr-136 Genes (30)TPRN, WRB, IFITM2, LILRA5, C2orf88, RILPL1, TUBB4B, KAZN, FAM72D, GAL3ST4, SREBF2, CENPW, SARNP, MFSD2B, FGFR1OP, GPC2, SRA1, LBH, FAM200A, OST4, KIFC1, APOPT1, S1PR2, FOXJ1, TGIF1 Regulons (34)R-1265, R-2164, R-193, R-3073, R-638, R-2640, R-2531, R-2238, R-331, R-0, R-339, R-2845, R-1902, R-2701, R-1452, R-702, R-695, R-2566, R-1421, R-2803, R-1827, R-2404, R-2705, R-1453, R-2266, R-87, R-834, R-779, R-1471, R-335, R-1571, R-970, R-2751, R-1629 |
| HBP1 | down-regulates | R-1833 | 1.75599 | Pr-24 Genes (7)CTC1, CITED4, UBQLN2, NMB, CHML, PPP1CB Regulons (8)R-2637, R-700, R-91, R-768, R-1882, R-3123, R-1833, R-2533 |
| E2F2 | up-regulates | R-2947 | -1.79304 | Pr-102 Genes (10)CCR4, KPNA4, NANOS3, NHLRC1, HIST3H2BB, DDX42, SH3D21, ZNF345, PINX1, CCPG1 Regulons (13)R-367, R-985, R-553, R-2155, R-2062, R-1380, R-2947, R-1355, R-1937, R-3060, R-769, R-522, R-2706 |
| ZBTB16 | down-regulates | R-586 | 1.81277 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| RFX3 | down-regulates | R-1670 | -1.81286 | Pr-4 Genes (37)B3GNT4, ZNF575, CRACR2B, ALS2CL, TCAIM, MED14, ADO, SFXN4, TM2D3, GAS2L1, EIF4EBP1, COL4A5, LRRK2, MXD3, ZBED8, CFAP97D1, WDR92, TMEM141, USP51, ZNF260, MTRNR2L8, CLLU1, CHURC1, CEP95, MRPL12, RPS10-NUDT3, YY1, BACH2, E2F2 Regulons (47)R-295, R-2879, R-2639, R-2318, R-3043, R-1908, R-1695, R-1554, R-2485, R-1767, R-777, R-443, R-1753, R-2114, R-1585, R-2824, R-1670, R-560, R-293, R-773, R-2432, R-270, R-2099, R-778, R-1778, R-1633, R-1277, R-1463, R-818, R-176, R-1573, R-1468, R-2599, R-2799, R-68, R-2950, R-2767, R-1174, R-990, R-2658, R-2221, R-2487, R-1684, R-3051, R-2813, R-1017, R-506 |
| E2F2 | up-regulates | R-2945 | 1.88745 | Pr-133 Genes (6)UCP3, GJD4, ACOT4, HNRNPA0, ZCWPW2 Regulons (7)R-3071, R-1940, R-2231, R-372, R-2200, R-2945, R-2989 |
| NRF1 | down-regulates | R-2705 | 1.91369 | Pr-136 Genes (30)TPRN, WRB, IFITM2, LILRA5, C2orf88, RILPL1, TUBB4B, KAZN, FAM72D, GAL3ST4, SREBF2, CENPW, SARNP, MFSD2B, FGFR1OP, GPC2, SRA1, LBH, FAM200A, OST4, KIFC1, APOPT1, S1PR2, FOXJ1, TGIF1 Regulons (34)R-1265, R-2164, R-193, R-3073, R-638, R-2640, R-2531, R-2238, R-331, R-0, R-339, R-2845, R-1902, R-2701, R-1452, R-702, R-695, R-2566, R-1421, R-2803, R-1827, R-2404, R-2705, R-1453, R-2266, R-87, R-834, R-779, R-1471, R-335, R-1571, R-970, R-2751, R-1629 |
| CREB1 | down-regulates | R-274 | -1.97415 | Pr-10 Genes (26)ATAD5, MANEAL, RBM34, MAN2A2, AMZ2, VKORC1L1, TLE1, ANKRD36B, CXorf40B, PCNX3, ENTPD4, FITM2, GFPT1, FICD, R3HDM4, HSPA1B, TMEM231, CDKL4, RAB12, ANKRD28, ZNF844, ERCC6, BORCS8-MEF2B Regulons (27)R-1850, R-2412, R-276, R-1536, R-2572, R-755, R-607, R-2204, R-1353, R-1673, R-903, R-571, R-2217, R-2657, R-2774, R-448, R-2892, R-1205, R-757, R-1976, R-1918, R-2149, R-2491, R-2302, R-274, R-588, R-95 |
| HBP1 | down-regulates | R-1844 | 1.97565 | Pr-73 Genes (4)IFITM5, NOL7, HSBP1, CEBPE Regulons (8)R-2102, R-1844, R-3075, R-1760, R-1830, R-173, R-781, R-2770 |
| RFX3 | down-regulates | R-1675 | 2.03925 | Pr-121 |
| STAT4 | down-regulates | R-2649 | -2.07524 | Pr-86 Genes (14)ARHGEF12, HTT, KTI12, MACO1, CCNI2, LEPROT, WBP1, JMJD7, ETV5, PCDHGA10, HSF4, TRIM28, MIXL1 Regulons (28)R-968, R-1987, R-3193, R-2211, R-379, R-2240, R-452, R-2649, R-1141, R-3044, R-2159, R-992, R-2877, R-1422, R-33, R-1867, R-2544, R-2050, R-1136, R-1587, R-2478, R-1576, R-2693, R-2605, R-2355, R-2743, R-2253, R-2270 |
| POU2F1 | down-regulates | R-87 | 2.07888 | Pr-136 Genes (30)TPRN, WRB, IFITM2, LILRA5, C2orf88, RILPL1, TUBB4B, KAZN, FAM72D, GAL3ST4, SREBF2, CENPW, SARNP, MFSD2B, FGFR1OP, GPC2, SRA1, LBH, FAM200A, OST4, KIFC1, APOPT1, S1PR2, FOXJ1, TGIF1 Regulons (34)R-1265, R-2164, R-193, R-3073, R-638, R-2640, R-2531, R-2238, R-331, R-0, R-339, R-2845, R-1902, R-2701, R-1452, R-702, R-695, R-2566, R-1421, R-2803, R-1827, R-2404, R-2705, R-1453, R-2266, R-87, R-834, R-779, R-1471, R-335, R-1571, R-970, R-2751, R-1629 |
| XBP1 | up-regulates | R-3062 | -2.11726 | Pr-25 Genes (9)RNPEP, RUFY1, ZNF664, TRNAU1AP, CLEC4G, SRC, HLA-F, RTL5 Regulons (9)R-974, R-1686, R-160, R-709, R-2312, R-2984, R-2341, R-2802, R-3062 |
| IKZF1 | down-regulates | R-996 | 2.22566 | Pr-121 |
| TCF7L1 | down-regulates | R-3170 | -2.27892 | Pr-14 Genes (17)TMEM70, TUBB6, PNMA1, CASKIN2, ANXA2R, MLF1, ARID3B, SLC17A8, FZD2, PLAG1, SLC8A1, SEMA4B, NOXA1, AKR1C3, MPV17L2 Regulons (18)R-1002, R-1429, R-1659, R-894, R-77, R-1832, R-1545, R-184, R-2284, R-2223, R-2075, R-2878, R-2606, R-1398, R-2952, R-1932, R-3170, R-2014 |
| HBP1 | down-regulates | R-1845 | -2.40009 | Pr-6 Genes (31)SART1, C11orf68, TALDO1, GPR150, ZNF543, COX14, ZNF571, KCTD2, PRKAG1, CSF1R, VMO1, SMDT1, SF3A3, TTC32, XPOT, KRBA2, MED12, APOBR, SDR42E1, FMNL1, ZBTB37, L3MBTL1, TRABD2A, CD55, ZNF34, DCHS2, CRIP1, NDUFA7 Regulons (31)R-46, R-2648, R-3177, R-869, R-2895, R-64, R-940, R-1917, R-3120, R-435, R-697, R-2958, R-886, R-1865, R-2783, R-1396, R-1420, R-1057, R-2768, R-2047, R-2528, R-2603, R-557, R-178, R-2874, R-70, R-2298, R-2329, R-2561, R-651, R-1845 |
| BBX | down-regulates | R-1533 | 2.412 | Pr-137 Genes (22)KCNE3, SUGCT, SLC35A4, COX8A, PRR15, PFN4, FAM91A1, TMEM94, C14orf28, CMTR2, NQO1, FAM120C, PTPN1, SLC25A29, TMA16, MZT1, CSNK1E, KCTD7, CDK3, CHMP1B, COMMD3-BMI1 Regulons (23)R-2269, R-1302, R-186, R-1876, R-790, R-972, R-782, R-1579, R-1150, R-704, R-1950, R-1175, R-1457, R-1988, R-1345, R-713, R-3084, R-291, R-784, R-1348, R-2965, R-1533, R-1377 |
| RARA | down-regulates | R-169 | 2.42125 | Pr-138 Genes (9)SYNE3, SEC24C, WSCD1, RAP2B, ODF3L1, SEMA4A, SLC9A6, PATL2, C2orf15 Regulons (12)R-1666, R-2981, R-2567, R-1177, R-133, R-3011, R-472, R-11, R-169, R-2271, R-1668, R-1842 |
| ZBTB16 | down-regulates | R-588 | -2.42313 | Pr-10 Genes (26)ATAD5, MANEAL, RBM34, MAN2A2, AMZ2, VKORC1L1, TLE1, ANKRD36B, CXorf40B, PCNX3, ENTPD4, FITM2, GFPT1, FICD, R3HDM4, HSPA1B, TMEM231, CDKL4, RAB12, ANKRD28, ZNF844, ERCC6, BORCS8-MEF2B Regulons (27)R-1850, R-2412, R-276, R-1536, R-2572, R-755, R-607, R-2204, R-1353, R-1673, R-903, R-571, R-2217, R-2657, R-2774, R-448, R-2892, R-1205, R-757, R-1976, R-1918, R-2149, R-2491, R-2302, R-274, R-588, R-95 |
| FOXJ3 | down-regulates | R-2877 | -2.43517 | Pr-86 Genes (14)ARHGEF12, HTT, KTI12, MACO1, CCNI2, LEPROT, WBP1, JMJD7, ETV5, PCDHGA10, HSF4, TRIM28, MIXL1 Regulons (28)R-968, R-1987, R-3193, R-2211, R-379, R-2240, R-452, R-2649, R-1141, R-3044, R-2159, R-992, R-2877, R-1422, R-33, R-1867, R-2544, R-2050, R-1136, R-1587, R-2478, R-1576, R-2693, R-2605, R-2355, R-2743, R-2253, R-2270 |
| IKZF1 | down-regulates | R-990 | -2.55623 | Pr-4 Genes (37)B3GNT4, ZNF575, CRACR2B, ALS2CL, TCAIM, MED14, ADO, SFXN4, TM2D3, GAS2L1, EIF4EBP1, COL4A5, LRRK2, MXD3, ZBED8, CFAP97D1, WDR92, TMEM141, USP51, ZNF260, MTRNR2L8, CLLU1, CHURC1, CEP95, MRPL12, RPS10-NUDT3, YY1, BACH2, E2F2 Regulons (47)R-295, R-2879, R-2639, R-2318, R-3043, R-1908, R-1695, R-1554, R-2485, R-1767, R-777, R-443, R-1753, R-2114, R-1585, R-2824, R-1670, R-560, R-293, R-773, R-2432, R-270, R-2099, R-778, R-1778, R-1633, R-1277, R-1463, R-818, R-176, R-1573, R-1468, R-2599, R-2799, R-68, R-2950, R-2767, R-1174, R-990, R-2658, R-2221, R-2487, R-1684, R-3051, R-2813, R-1017, R-506 |
| RFX3 | down-regulates | R-1674 | -2.69724 | Pr-19 Genes (8)COL4A6, HSD17B8, CPT1B, PPM1N, LYN Regulons (11)R-51, R-392, R-789, R-2483, R-2, R-2551, R-501, R-1967, R-1674, R-2202, R-1064 |
| HBP1 | down-regulates | R-1830 | 2.71345 | Pr-73 Genes (4)IFITM5, NOL7, HSBP1, CEBPE Regulons (8)R-2102, R-1844, R-3075, R-1760, R-1830, R-173, R-781, R-2770 |
| NFATC1 | down-regulates | R-2202 | -2.7244 | Pr-19 Genes (8)COL4A6, HSD17B8, CPT1B, PPM1N, LYN Regulons (11)R-51, R-392, R-789, R-2483, R-2, R-2551, R-501, R-1967, R-1674, R-2202, R-1064 |
| HBP1 | down-regulates | R-1829 | -2.78136 | Pr-17 Genes (10)DNAJC9, PPP5D1, RNF103, NFS1, IFITM10, ZCCHC3, HMBS, SMIM6, CORO7, CUX1 Regulons (16)R-1961, R-385, R-1001, R-3124, R-3035, R-1194, R-2286, R-1716, R-1399, R-598, R-1829, R-2330, R-358, R-1465, R-470, R-2997 |
| NRF1 | down-regulates | R-2703 | 2.85746 | Pr-72 Genes (3)ZNF250, ZNF625 Regulons (13)R-1955, R-2746, R-714, R-693, R-705, R-2703, R-2530, R-1020, R-554, R-1391, R-2710, R-1743, R-831 |
| NFIA | up-regulates | R-354 | -2.9087 | Pr-60 Genes (13)MYLPF, CXCR2, SCRIB, RNF41, PPP1R27, FAM167B, SIGIRR, NOC2L, KLHL14, SELENOH, STARD10, TNFSF12, SELENOP Regulons (16)R-12, R-2753, R-314, R-2433, R-1411, R-2357, R-2343, R-1509, R-1392, R-1657, R-2736, R-3179, R-1338, R-1887, R-354, R-1354 |
| RFX3 | down-regulates | R-1661 | 2.92167 | Pr-52 Genes (3)LTN1, DHFR Regulons (14)R-2811, R-2250, R-384, R-1233, R-1661, R-2629, R-3077, R-1986, R-1548, R-305, R-2978, R-870, R-2716, R-496 |
| PARP1 | up-regulates | R-2638 | 3.03283 | Pr-126 Genes (12)MTURN, SAMD7, ISG15, TYW1, SFT2D2, PTPRCAP, APOBEC3G, MRPL33, CDK11B, PRR5-ARHGAP8, TERB1, UTP14C Regulons (15)R-1312, R-1710, R-128, R-366, R-2612, R-1442, R-981, R-2739, R-1647, R-1766, R-542, R-2672, R-2543, R-2638, R-3053 |
| JDP2 | down-regulates | R-358 | -3.10262 | Pr-17 Genes (10)DNAJC9, PPP5D1, RNF103, NFS1, IFITM10, ZCCHC3, HMBS, SMIM6, CORO7, CUX1 Regulons (16)R-1961, R-385, R-1001, R-3124, R-3035, R-1194, R-2286, R-1716, R-1399, R-598, R-1829, R-2330, R-358, R-1465, R-470, R-2997 |
| MAFK | down-regulates | R-2813 | -3.12874 | Pr-4 Genes (37)B3GNT4, ZNF575, CRACR2B, ALS2CL, TCAIM, MED14, ADO, SFXN4, TM2D3, GAS2L1, EIF4EBP1, COL4A5, LRRK2, MXD3, ZBED8, CFAP97D1, WDR92, TMEM141, USP51, ZNF260, MTRNR2L8, CLLU1, CHURC1, CEP95, MRPL12, RPS10-NUDT3, YY1, BACH2, E2F2 Regulons (47)R-295, R-2879, R-2639, R-2318, R-3043, R-1908, R-1695, R-1554, R-2485, R-1767, R-777, R-443, R-1753, R-2114, R-1585, R-2824, R-1670, R-560, R-293, R-773, R-2432, R-270, R-2099, R-778, R-1778, R-1633, R-1277, R-1463, R-818, R-176, R-1573, R-1468, R-2599, R-2799, R-68, R-2950, R-2767, R-1174, R-990, R-2658, R-2221, R-2487, R-1684, R-3051, R-2813, R-1017, R-506 |
| RARA | down-regulates | R-153 | -3.1944 | Pr-61 Genes (2)HLA-DQA1, SCARF2 Regulons (13)R-1530, R-2176, R-151, R-637, R-153, R-2896, R-612, R-909, R-2375, R-1414, R-2980, R-653, R-1529 |
| RELA | down-regulates | R-1464 | 3.32257 | Pr-70 Genes (1)SNURF Regulons (12)R-1694, R-505, R-1464, R-296, R-1781, R-2976, R-1469, R-73, R-942, R-1847, R-2281, R-2992 |
| RELA | down-regulates | R-1465 | -3.41018 | Pr-17 Genes (10)DNAJC9, PPP5D1, RNF103, NFS1, IFITM10, ZCCHC3, HMBS, SMIM6, CORO7, CUX1 Regulons (16)R-1961, R-385, R-1001, R-3124, R-3035, R-1194, R-2286, R-1716, R-1399, R-598, R-1829, R-2330, R-358, R-1465, R-470, R-2997 |
| SMAD4 | down-regulates | R-2355 | -3.44256 | Pr-86 Genes (14)ARHGEF12, HTT, KTI12, MACO1, CCNI2, LEPROT, WBP1, JMJD7, ETV5, PCDHGA10, HSF4, TRIM28, MIXL1 Regulons (28)R-968, R-1987, R-3193, R-2211, R-379, R-2240, R-452, R-2649, R-1141, R-3044, R-2159, R-992, R-2877, R-1422, R-33, R-1867, R-2544, R-2050, R-1136, R-1587, R-2478, R-1576, R-2693, R-2605, R-2355, R-2743, R-2253, R-2270 |
| RARA | down-regulates | R-166 | -3.60154 | Pr-20 Genes (5)ZNF530, ERCC6L, NAP1L4, ZNF324B, RNASE4 Regulons (10)R-2300, R-2901, R-1936, R-2733, R-987, R-2297, R-3189, R-166, R-2726, R-2484 |
| RFX3 | down-regulates | R-1668 | 3.60705 | Pr-138 Genes (9)SYNE3, SEC24C, WSCD1, RAP2B, ODF3L1, SEMA4A, SLC9A6, PATL2, C2orf15 Regulons (12)R-1666, R-2981, R-2567, R-1177, R-133, R-3011, R-472, R-11, R-169, R-2271, R-1668, R-1842 |
| HBP1 | down-regulates | R-1842 | 3.856 | Pr-138 Genes (9)SYNE3, SEC24C, WSCD1, RAP2B, ODF3L1, SEMA4A, SLC9A6, PATL2, C2orf15 Regulons (12)R-1666, R-2981, R-2567, R-1177, R-133, R-3011, R-472, R-11, R-169, R-2271, R-1668, R-1842 |
| POU2F1 | down-regulates | R-88 | 4.3225 | Pr-69 |
| NRF1 | down-regulates | R-2710 | 4.52843 | Pr-72 Genes (3)ZNF250, ZNF625 Regulons (13)R-1955, R-2746, R-714, R-693, R-705, R-2703, R-2530, R-1020, R-554, R-1391, R-2710, R-1743, R-831 |
| RFX3 | down-regulates | R-1665 | 4.55866 | Pr-69 |
| POU2F1 | down-regulates | R-73 | 4.62299 | Pr-70 Genes (1)SNURF Regulons (12)R-1694, R-505, R-1464, R-296, R-1781, R-2976, R-1469, R-73, R-942, R-1847, R-2281, R-2992 |
| POU2F1 | down-regulates | R-86 | 4.85124 | Pr-49 Genes (0)Regulons (12)R-1473, R-1514, R-441, R-1889, R-2611, R-2295, R-47, R-37, R-1873, R-86, R-497, R-1965 |
| HBP1 | down-regulates | R-1847 | 4.92709 | Pr-70 Genes (1)SNURF Regulons (12)R-1694, R-505, R-1464, R-296, R-1781, R-2976, R-1469, R-73, R-942, R-1847, R-2281, R-2992 |
| NFATC1 | down-regulates | R-2199 | -5.63196 | Pr-135 Genes (24)LYSMD3, MTHFR, NEB, MX2, PCBP3, CHRM5, WDR53, TOR3A, CCDC30, ZDHHC17, SLC38A3, ZNF429, PIWIL2, SLC22A5, MCMBP, PRIM1, SZT2, HNRNPUL2, CEBPD, ATXN1L, N4BP2L2, MARS2 Regulons (38)R-311, R-2304, R-610, R-973, R-901, R-2103, R-341, R-717, R-2293, R-2067, R-337, R-1454, R-979, R-1555, R-2536, R-2985, R-1455, R-2617, R-1956, R-2167, R-791, R-785, R-672, R-2847, R-2083, R-1091, R-1890, R-1299, R-1874, R-2406, R-1269, R-1942, R-389, R-2263, R-1692, R-2199, R-1523, R-1230 |
| PARP1 | up-regulates | R-2636 | 8.12838 | Pr-68 Genes (0)Regulons (18)R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627 |
| E2F2 | up-regulates | R-2942 | 8.59906 | Pr-68 Genes (0)Regulons (18)R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627 |
| E2F8 | up-regulates | R-1626 | 8.62493 | Pr-68 Genes (0)Regulons (18)R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627 |
| E2F1 | up-regulates | R-2173 | 8.76486 | Pr-68 Genes (0)Regulons (18)R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627 |
| E2F1 | up-regulates | R-2172 | 8.82921 | Pr-68 Genes (0)Regulons (18)R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627 |
| E2F2 | up-regulates | R-2944 | 8.90615 | Pr-68 Genes (0)Regulons (18)R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627 |
| E2F8 | up-regulates | R-1627 | 9.26408 | Pr-68 Genes (0)Regulons (18)R-283, R-2319, R-1096, R-2518, R-2636, R-1931, R-2043, R-1393, R-2046, R-635, R-614, R-2942, R-1626, R-1384, R-2173, R-2172, R-2944, R-1627 |
