Causal Mechanistic Flows with regulons in program Pr-81
| Mutation | Role | Regulator | Role | Regulon | Hazard Ratio | # regulon genes | Transcriptional Program |
|---|---|---|---|---|---|---|---|
| CYLD | up-regulates | ETS1 | activates | R-6 | 3.22139 | 8 | Pr-81 |
| del1p | up-regulates | MYB | activates | R-625 | 3.48247 | 6 | Pr-81 |
| FGFR3 | down-regulates | ETS1 | activates | R-6 | 3.22139 | 8 | Pr-81 |
| MACF1 | up-regulates | MYB | activates | R-625 | 3.48247 | 6 | Pr-81 |
| NFKB2 | up-regulates | ETS1 | activates | R-6 | 3.22139 | 8 | Pr-81 |
| PRKD2 | down-regulates | ETS1 | activates | R-6 | 3.22139 | 8 | Pr-81 |
| RNASeq_FGFR3_Call | down-regulates | ETS1 | activates | R-6 | 3.22139 | 8 | Pr-81 |
| RNASeq_MAFA_Call | up-regulates | ARID3A | activates | R-1351 | 2.72525 | 7 | Pr-81 |
| RNASeq_MAFA_Call | up-regulates | ETS1 | activates | R-6 | 3.22139 | 8 | Pr-81 |
| RNASeq_MAFA_Call | up-regulates | MYB | activates | R-625 | 3.48247 | 6 | Pr-81 |
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