Program

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

Causal Mechanistic Flows with regulons in program Pr-47

MutationRoleRegulatorRoleRegulonHazard Ratio# regulon genesTranscriptional Program
DNAH10up-regulatesZBTB16repressesR-591-3.274416Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

FAM46Cdown-regulatesZBTB16repressesR-591-3.274416Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

IRF4up-regulatesZBTB16repressesR-591-3.274416Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

PRKD2up-regulatesZBTB16repressesR-591-3.274416Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

t(11;14)up-regulatesZBTB16repressesR-591-3.274416Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

RNASeq_FGFR3_Callup-regulatesZBTB16repressesR-591-3.274416Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

t(4;14)up-regulatesZBTB16repressesR-591-3.274416Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

t(11;14)_cytogeneticup-regulatesZBTB16repressesR-591-3.274416Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

t(4;14)_cytogeneticup-regulatesZBTB16repressesR-591-3.274416Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

DIS3down-regulatesFOXO3activatesR-2773-3.3731315Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

DNAH10down-regulatesFOXO3activatesR-2773-3.3731315Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

FAM46Cup-regulatesFOXO3activatesR-2773-3.3731315Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

HUWE1down-regulatesFOXO3activatesR-2773-3.3731315Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

IRF4down-regulatesFOXO3activatesR-2773-3.3731315Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

NRASup-regulatesFOXO3activatesR-2773-3.3731315Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

PRKD2down-regulatesFOXO3activatesR-2773-3.3731315Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

t(11;14)down-regulatesFOXO3activatesR-2773-3.3731315Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

SETD2down-regulatesFOXO3activatesR-2773-3.3731315Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

t(11;14)_cytogeneticdown-regulatesFOXO3activatesR-2773-3.3731315Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

t(4;14)_cytogeneticdown-regulatesFOXO3activatesR-2773-3.3731315Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

AHNAK2down-regulatesIRF9activatesR-1156-3.438887Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

SVEP1down-regulatesIRF9activatesR-1156-3.438887Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

TRAF3down-regulatesIRF9activatesR-1156-3.438887Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

FAM46Cdown-regulatesENSG00000176887repressesR-1897-3.609636Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

FRAS1up-regulatesENSG00000176887repressesR-1897-3.609636Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

HUWE1up-regulatesENSG00000176887repressesR-1897-3.609636Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

IRF4up-regulatesENSG00000176887repressesR-1897-3.609636Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

LTBup-regulatesENSG00000176887repressesR-1897-3.609636Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

PRKD2up-regulatesENSG00000176887repressesR-1897-3.609636Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

t(11;14)up-regulatesENSG00000176887repressesR-1897-3.609636Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

RNASeq_FGFR3_Callup-regulatesENSG00000176887repressesR-1897-3.609636Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

t(4;14)up-regulatesENSG00000176887repressesR-1897-3.609636Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

TP53up-regulatesENSG00000176887repressesR-1897-3.609636Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

t(11;14)_cytogeneticup-regulatesENSG00000176887repressesR-1897-3.609636Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

t(4;14)_cytogeneticup-regulatesENSG00000176887repressesR-1897-3.609636Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

HUWE1down-regulatesPOU2F2activatesR-2520-3.92296Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

IRF4down-regulatesPOU2F2activatesR-2520-3.92296Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

t(11;14)down-regulatesPOU2F2activatesR-2520-3.92296Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

RNASeq_CCND3_Calldown-regulatesPOU2F2activatesR-2520-3.92296Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

TP53down-regulatesPOU2F2activatesR-2520-3.92296Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

t(11;14)_cytogeneticdown-regulatesPOU2F2activatesR-2520-3.92296Pr-47

Genes (0)

Regulons (5)

R-591, R-2773, R-1156, R-1897, R-2520

Regulons in program Pr-47

Regulon Cox Hazard Ratio # genes # causal flows
R-591-3.2744169
R-2773-3.373131511
R-1156-3.4388873
R-1897-3.60963612
R-2520-3.922966

Genes in program Pr-47

EnsEMBL IdEntrez IdPreferred

Program Survival Plots

Kaplan-Meier curves demonstrating the sub-stratification of clinical subtypes based upon the network activity of the most predictive individual or pair of genes as determined by the LASSO predictions