| TP53 | down-regulates | R-362 | 0.0022486 | Pr-5 Genes (32)ZNF25, POLD4, CLK2, EPS8L2, PIDD1, JUN, AGTRAP, C2orf69, GRINA, PTPN11, PITPNB, DNAH14, C15orf41, KIF18B, DUSP28, CFAP126, ZFP62, MYO5A, FAM114A1, FAM118B, PIM3, ZNF627, TEX45, ITPRIPL1, MRPL53, TECPR1, RNPS1, CFAP44, ZNF726, EML6, LOC441155 Regulons (33)R-362, R-1924, R-1337, R-92, R-1207, R-3137, R-2527, R-2775, R-2562, R-1927, R-2749, R-2109, R-1198, R-1854, R-275, R-2883, R-3016, R-286, R-1350, R-2038, R-148, R-42, R-3198, R-2569, R-2282, R-581, R-590, R-2346, R-2265, R-2473, R-2377, R-2110, R-1385 |
| ZNF740 | up-regulates | R-396 | -0.00292173 | Pr-134 Genes (104)MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1 Regulons (119)R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272 |
| NFAT5 | up-regulates | R-46 | 0.00489595 | Pr-6 Genes (31)SART1, C11orf68, TALDO1, GPR150, ZNF543, COX14, ZNF571, KCTD2, PRKAG1, CSF1R, VMO1, SMDT1, SF3A3, TTC32, XPOT, KRBA2, MED12, APOBR, SDR42E1, FMNL1, ZBTB37, L3MBTL1, TRABD2A, CD55, ZNF34, DCHS2, CRIP1, NDUFA7 Regulons (31)R-46, R-2648, R-3177, R-869, R-2895, R-64, R-940, R-1917, R-3120, R-435, R-697, R-2958, R-886, R-1865, R-2783, R-1396, R-1420, R-1057, R-2768, R-2047, R-2528, R-2603, R-557, R-178, R-2874, R-70, R-2298, R-2329, R-2561, R-651, R-1845 |
| STAT5A | up-regulates | R-2169 | 0.00587927 | Pr-134 Genes (104)MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1 Regulons (119)R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272 |
| ZFX | up-regulates | R-1924 | 0.00674942 | Pr-5 Genes (32)ZNF25, POLD4, CLK2, EPS8L2, PIDD1, JUN, AGTRAP, C2orf69, GRINA, PTPN11, PITPNB, DNAH14, C15orf41, KIF18B, DUSP28, CFAP126, ZFP62, MYO5A, FAM114A1, FAM118B, PIM3, ZNF627, TEX45, ITPRIPL1, MRPL53, TECPR1, RNPS1, CFAP44, ZNF726, EML6, LOC441155 Regulons (33)R-362, R-1924, R-1337, R-92, R-1207, R-3137, R-2527, R-2775, R-2562, R-1927, R-2749, R-2109, R-1198, R-1854, R-275, R-2883, R-3016, R-286, R-1350, R-2038, R-148, R-42, R-3198, R-2569, R-2282, R-581, R-590, R-2346, R-2265, R-2473, R-2377, R-2110, R-1385 |
| TEAD1 | down-regulates | R-1217 | -0.00924721 | Pr-116 |
| RORA | down-regulates | R-2269 | -0.010155 | Pr-137 Genes (22)KCNE3, SUGCT, SLC35A4, COX8A, PRR15, PFN4, FAM91A1, TMEM94, C14orf28, CMTR2, NQO1, FAM120C, PTPN1, SLC25A29, TMA16, MZT1, CSNK1E, KCTD7, CDK3, CHMP1B, COMMD3-BMI1 Regulons (23)R-2269, R-1302, R-186, R-1876, R-790, R-972, R-782, R-1579, R-1150, R-704, R-1950, R-1175, R-1457, R-1988, R-1345, R-713, R-3084, R-291, R-784, R-1348, R-2965, R-1533, R-1377 |
| SPI1 | up-regulates | R-2619 | 0.0114715 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| STAT1 | down-regulates | R-3071 | -0.0145432 | Pr-133 Genes (6)UCP3, GJD4, ACOT4, HNRNPA0, ZCWPW2 Regulons (7)R-3071, R-1940, R-2231, R-372, R-2200, R-2945, R-2989 |
| TFEB | up-regulates | R-889 | 0.0284888 | Pr-39 Genes (11)PAAF1, KDF1, CD28, MAF, TBK1, PGP, FCAR, APOL6, SIGLEC14, MTRNR2L2 Regulons (17)R-889, R-2846, R-1954, R-558, R-2141, R-1857, R-708, R-378, R-1343, R-2900, R-1704, R-2347, R-2988, R-2552, R-1245, R-474, R-2797 |
| PAX6 | down-regulates | R-1556 | 0.0296134 | Pr-117 Genes (51)LRRC25, MRPL48, CNTD1, EFCAB5, ZDHHC13, PPFIA3, TBL1XR1, IL17RA, POLR2L, KLHL28, SHARPIN, PHLDA2, IST1, SKA2, JRKL, TRMT12, WDR27, ADSSL1, SHC4, YTHDF3, ZNF267, OR2AG2, PTAR1, SLX4, PRPF40A, RABL6, ANXA4, WDR5B, MAFG, TOPORS, KCNMB2, MFAP3L, PHACTR4, TRIQK, SUPT4H1, LTC4S, DDX47, FIS1, CKLF, FAM185A, RARB, IRF4, HOXA3 Regulons (53)R-2087, R-1556, R-2707, R-342, R-2610, R-2252, R-62, R-1904, R-1388, R-1266, R-2882, R-369, R-451, R-1677, R-1495, R-1591, R-771, R-2371, R-2535, R-1846, R-945, R-500, R-986, R-2995, R-2886, R-630, R-2738, R-2991, R-1735, R-1032, R-643, R-2069, R-1485, R-2179, R-2961, R-157, R-2336, R-2142, R-2358, R-1271, R-1489, R-1734, R-2090, R-1742, R-2070, R-3168, R-2704, R-994, R-2335, R-1786, R-539, R-2068, R-1929 |
| ENSG00000176399 | up-regulates | R-1072 | 0.0376465 | Pr-105 Genes (8)ERCC4, IDH2, ZNF490, FAM83G, ASPH, EXOC3L4, SLC48A1 Regulons (8)R-1072, R-2880, R-821, R-1432, R-81, R-2380, R-582, R-3000 |
| JUN | up-regulates | R-1182 | 0.0408673 | Pr-75 |
| ENSG00000054598 | up-regulates | R-1002 | -0.0418558 | Pr-14 Genes (17)TMEM70, TUBB6, PNMA1, CASKIN2, ANXA2R, MLF1, ARID3B, SLC17A8, FZD2, PLAG1, SLC8A1, SEMA4B, NOXA1, AKR1C3, MPV17L2 Regulons (18)R-1002, R-1429, R-1659, R-894, R-77, R-1832, R-1545, R-184, R-2284, R-2223, R-2075, R-2878, R-2606, R-1398, R-2952, R-1932, R-3170, R-2014 |
| ELK3 | up-regulates | R-2846 | -0.0445985 | Pr-39 Genes (11)PAAF1, KDF1, CD28, MAF, TBK1, PGP, FCAR, APOL6, SIGLEC14, MTRNR2L2 Regulons (17)R-889, R-2846, R-1954, R-558, R-2141, R-1857, R-708, R-378, R-1343, R-2900, R-1704, R-2347, R-2988, R-2552, R-1245, R-474, R-2797 |
| ENSG00000245848 | up-regulates | R-1655 | 0.0553209 | Pr-134 Genes (104)MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1 Regulons (119)R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272 |
| FOXP1 | up-regulates | R-3134 | 0.0646792 | Pr-56 Genes (7)BAIAP2, ATOX1, COX5A, MCFD2, NBR1, ANKRD39 Regulons (7)R-3134, R-1006, R-190, R-2139, R-1872, R-2059, R-2550 |
| TRAF4 | up-regulates | R-3037 | -0.0698997 | Pr-2 Genes (47)MSRA, PLEKHF2, NUPR1, IP6K1, TCP11L1, SPHK1, TYMS, FAM89B, WDR73, IRX3, ACAD9, CD151, KCNJ10, ARL6IP6, ODF3B, MPI, HYI, SPTY2D1, DAND5, ELMOD2, CDC42EP4, MAF1, SERTAD2, GLIPR1L2, LSMEM1, HIST3H2A, C5orf24, GINS3, RAD51B, MXRA7, BRICD5, RUVBL2, RBM12B, BRWD1, ANKRD37, TTC30B, SFI1, CTR9, CCDC167, PDXP Regulons (47)R-1855, R-2267, R-3037, R-486, R-2717, R-878, R-363, R-2104, R-631, R-3178, R-563, R-1911, R-436, R-183, R-2977, R-78, R-2479, R-2411, R-1825, R-49, R-272, R-390, R-1869, R-1831, R-2225, R-1586, R-775, R-535, R-1660, R-796, R-1574, R-1561, R-3126, R-2309, R-1717, R-2283, R-1341, R-2662, R-3007, R-2873, R-599, R-1189, R-2486, R-24, R-3064, R-570, R-288 |
| FOXJ2 | up-regulates | R-1429 | 0.070253 | Pr-14 Genes (17)TMEM70, TUBB6, PNMA1, CASKIN2, ANXA2R, MLF1, ARID3B, SLC17A8, FZD2, PLAG1, SLC8A1, SEMA4B, NOXA1, AKR1C3, MPV17L2 Regulons (18)R-1002, R-1429, R-1659, R-894, R-77, R-1832, R-1545, R-184, R-2284, R-2223, R-2075, R-2878, R-2606, R-1398, R-2952, R-1932, R-3170, R-2014 |
| ELF3 | up-regulates | R-2148 | 0.0747421 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| DDIT3 | up-regulates | R-486 | -0.0796563 | Pr-2 Genes (47)MSRA, PLEKHF2, NUPR1, IP6K1, TCP11L1, SPHK1, TYMS, FAM89B, WDR73, IRX3, ACAD9, CD151, KCNJ10, ARL6IP6, ODF3B, MPI, HYI, SPTY2D1, DAND5, ELMOD2, CDC42EP4, MAF1, SERTAD2, GLIPR1L2, LSMEM1, HIST3H2A, C5orf24, GINS3, RAD51B, MXRA7, BRICD5, RUVBL2, RBM12B, BRWD1, ANKRD37, TTC30B, SFI1, CTR9, CCDC167, PDXP Regulons (47)R-1855, R-2267, R-3037, R-486, R-2717, R-878, R-363, R-2104, R-631, R-3178, R-563, R-1911, R-436, R-183, R-2977, R-78, R-2479, R-2411, R-1825, R-49, R-272, R-390, R-1869, R-1831, R-2225, R-1586, R-775, R-535, R-1660, R-796, R-1574, R-1561, R-3126, R-2309, R-1717, R-2283, R-1341, R-2662, R-3007, R-2873, R-599, R-1189, R-2486, R-24, R-3064, R-570, R-288 |
| IRF1 | up-regulates | R-180 | -0.0848453 | Pr-0 Genes (84)GPX2, BNIP3, METRNL, PUS1, SAMD12, CD163, SLC25A20, EFCAB13, EXOSC4, SAMD4B, CATSPERE, C14orf119, ARHGAP45, BBS12, EHMT1, SETD2, ZBTB20, RFX7, TSKU, SRPRA, SLC25A10, ASB7, UPP1, LIN9, CCR10, ZFP1, USP18, TNFAIP2, CDNF, SOCS1, METTL7A, PDE6G, SP1, P4HB, DRG1, CXorf38, MORF4L1, AIDA, WWOX, SAPCD2, PPP1CC, SPIN4, CXCR3, ZNF397, TPCN1, CMC1, GCNT1, FNBP1, RSBN1L, LOC100288637, TMPPE, ZC3H6, ZNF669, NANOS1, ALKBH2, JPT1, LIN54, HLA-DRB1, ZNF493, EPHB4, TRAPPC2B, SIAH1, ESRRG, TCF4, SERTAD1, ZNF398, ZNF257, ATG7, MPEG1, RPS4X, PNP, HMGN2, HIST2H2BF, COLQ, RPS29 Regulons (86)R-180, R-2076, R-2157, R-3164, R-3147, R-338, R-2156, R-2409, R-885, R-941, R-1192, R-556, R-3197, R-1572, R-999, R-636, R-902, R-2541, R-440, R-890, R-3175, R-767, R-1542, R-1336, R-2472, R-1698, R-2326, R-1906, R-269, R-772, R-647, R-3033, R-2100, R-2711, R-1394, R-3068, R-508, R-63, R-1916, R-1188, R-532, R-2135, R-997, R-1687, R-2951, R-1853, R-2220, R-577, R-585, R-2597, R-1021, R-3119, R-301, R-559, R-1560, R-175, R-2870, R-3015, R-66, R-595, R-3185, R-2905, R-433, R-290, R-381, R-2509, R-562, R-2798, R-2206, R-1418, R-60, R-3050, R-2073, R-611, R-2488, R-881, R-1095, R-2153, R-2553, R-2305, R-2656, R-1697, R-511, R-2185, R-1492, R-2555 |
| NRF1 | up-regulates | R-2707 | -0.0919786 | Pr-117 Genes (51)LRRC25, MRPL48, CNTD1, EFCAB5, ZDHHC13, PPFIA3, TBL1XR1, IL17RA, POLR2L, KLHL28, SHARPIN, PHLDA2, IST1, SKA2, JRKL, TRMT12, WDR27, ADSSL1, SHC4, YTHDF3, ZNF267, OR2AG2, PTAR1, SLX4, PRPF40A, RABL6, ANXA4, WDR5B, MAFG, TOPORS, KCNMB2, MFAP3L, PHACTR4, TRIQK, SUPT4H1, LTC4S, DDX47, FIS1, CKLF, FAM185A, RARB, IRF4, HOXA3 Regulons (53)R-2087, R-1556, R-2707, R-342, R-2610, R-2252, R-62, R-1904, R-1388, R-1266, R-2882, R-369, R-451, R-1677, R-1495, R-1591, R-771, R-2371, R-2535, R-1846, R-945, R-500, R-986, R-2995, R-2886, R-630, R-2738, R-2991, R-1735, R-1032, R-643, R-2069, R-1485, R-2179, R-2961, R-157, R-2336, R-2142, R-2358, R-1271, R-1489, R-1734, R-2090, R-1742, R-2070, R-3168, R-2704, R-994, R-2335, R-1786, R-539, R-2068, R-1929 |
| FOXJ2 | up-regulates | R-1436 | 0.0974287 | Pr-41 Genes (9)CABP4, SFN, YES1, CSTF2T, KLHL11, DEXI, SOCS3, HIST2H2BE, ZNF248 Regulons (10)R-1382, R-479, R-1436, R-1086, R-83, R-971, R-1757, R-2378, R-3091, R-677 |
| SREBF1 | up-regulates | R-1139 | 0.101608 | Pr-7 Genes (38)UFSP1, SLC35G1, IMP3, R3HDM2, RNF135, HKR1, ATP6AP2, SATB1, RBM10, CRELD2, SNRNP35, ZDHHC23, AMER1, PTRHD1, NDUFA6, MAFF, PRMT3, RGPD2, ATP6V0C, C16orf54, IRS2, MKL2, FAM86B2, PRR5, ZNF33A, XRCC6, TSC22D2, SLC6A9, ADAM32, NOL4L, SERPINA1, EME2, ENTPD7, PJA2 Regulons (39)R-1139, R-308, R-1195, R-2247, R-2754, R-1584, R-1923, R-1849, R-2345, R-370, R-226, R-1013, R-2065, R-2181, R-2145, R-2843, R-1003, R-1410, R-2796, R-3012, R-1347, R-3136, R-1650, R-543, R-53, R-2571, R-1879, R-1738, R-2557, R-1968, R-1562, R-3067, R-788, R-1840, R-2230, R-471, R-1667, R-3165, R-361 |
| TP53 | down-regulates | R-363 | 0.103829 | Pr-2 Genes (47)MSRA, PLEKHF2, NUPR1, IP6K1, TCP11L1, SPHK1, TYMS, FAM89B, WDR73, IRX3, ACAD9, CD151, KCNJ10, ARL6IP6, ODF3B, MPI, HYI, SPTY2D1, DAND5, ELMOD2, CDC42EP4, MAF1, SERTAD2, GLIPR1L2, LSMEM1, HIST3H2A, C5orf24, GINS3, RAD51B, MXRA7, BRICD5, RUVBL2, RBM12B, BRWD1, ANKRD37, TTC30B, SFI1, CTR9, CCDC167, PDXP Regulons (47)R-1855, R-2267, R-3037, R-486, R-2717, R-878, R-363, R-2104, R-631, R-3178, R-563, R-1911, R-436, R-183, R-2977, R-78, R-2479, R-2411, R-1825, R-49, R-272, R-390, R-1869, R-1831, R-2225, R-1586, R-775, R-535, R-1660, R-796, R-1574, R-1561, R-3126, R-2309, R-1717, R-2283, R-1341, R-2662, R-3007, R-2873, R-599, R-1189, R-2486, R-24, R-3064, R-570, R-288 |
| FOXO1 | up-regulates | R-1400 | 0.106473 | Pr-124 Genes (20)MYPOP, DMAP1, PER1, C1S, DENND5A, TSPYL2, KNTC1, TMEM105, LRCH3, ZBTB6, CFAP73, LILRB4, TNFRSF18, LITAF, ZNF665, IPO7, KMT2B Regulons (20)R-1400, R-1425, R-1962, R-1828, R-991, R-1083, R-1577, R-72, R-2158, R-3069, R-2814, R-1149, R-1631, R-182, R-1340, R-3034, R-3139, R-39, R-199, R-593 |
| ZNF740 | up-regulates | R-386 | 0.111482 | Pr-58 Genes (28)ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28)R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148 |
| VENTX | up-regulates | R-2117 | 0.118548 | Pr-134 Genes (104)MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1 Regulons (119)R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272 |
| XBP1 | down-regulates | R-3054 | 0.128472 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| RFX3 | up-regulates | R-1666 | 0.128531 | Pr-138 Genes (9)SYNE3, SEC24C, WSCD1, RAP2B, ODF3L1, SEMA4A, SLC9A6, PATL2, C2orf15 Regulons (12)R-1666, R-2981, R-2567, R-1177, R-133, R-3011, R-472, R-11, R-169, R-2271, R-1668, R-1842 |
| ARID3A | down-regulates | R-1337 | 0.134253 | Pr-5 Genes (32)ZNF25, POLD4, CLK2, EPS8L2, PIDD1, JUN, AGTRAP, C2orf69, GRINA, PTPN11, PITPNB, DNAH14, C15orf41, KIF18B, DUSP28, CFAP126, ZFP62, MYO5A, FAM114A1, FAM118B, PIM3, ZNF627, TEX45, ITPRIPL1, MRPL53, TECPR1, RNPS1, CFAP44, ZNF726, EML6, LOC441155 Regulons (33)R-362, R-1924, R-1337, R-92, R-1207, R-3137, R-2527, R-2775, R-2562, R-1927, R-2749, R-2109, R-1198, R-1854, R-275, R-2883, R-3016, R-286, R-1350, R-2038, R-148, R-42, R-3198, R-2569, R-2282, R-581, R-590, R-2346, R-2265, R-2473, R-2377, R-2110, R-1385 |
| FLI1 | down-regulates | R-790 | -0.135687 | Pr-137 Genes (22)KCNE3, SUGCT, SLC35A4, COX8A, PRR15, PFN4, FAM91A1, TMEM94, C14orf28, CMTR2, NQO1, FAM120C, PTPN1, SLC25A29, TMA16, MZT1, CSNK1E, KCTD7, CDK3, CHMP1B, COMMD3-BMI1 Regulons (23)R-2269, R-1302, R-186, R-1876, R-790, R-972, R-782, R-1579, R-1150, R-704, R-1950, R-1175, R-1457, R-1988, R-1345, R-713, R-3084, R-291, R-784, R-1348, R-2965, R-1533, R-1377 |
| TCF7L1 | up-regulates | R-3174 | -0.135953 | Pr-99 Genes (28)GNG7, ZBTB34, APOBEC3B, PSMG4, HSF1, PRPF39, ARL15, CERKL, MSL1, ZNF79, PLXNB2, YTHDF2, TLK1, TSEN15, CAPZA2, FCGR3A, LIME1, SMIM5, C6orf47, DENND6B, LIN52, RBMXL1, EMP2, TMEM167B, ZSCAN31, CDRT4 Regulons (31)R-3174, R-453, R-1770, R-3083, R-1212, R-648, R-2506, R-2709, R-1696, R-2314, R-2642, R-587, R-492, R-1891, R-3063, R-640, R-2162, R-3070, R-1834, R-188, R-2140, R-2317, R-1435, R-3129, R-699, R-3090, R-650, R-1007, R-2844, R-2311, R-606 |
| ETV5 | up-regulates | R-342 | 0.139146 | Pr-117 Genes (51)LRRC25, MRPL48, CNTD1, EFCAB5, ZDHHC13, PPFIA3, TBL1XR1, IL17RA, POLR2L, KLHL28, SHARPIN, PHLDA2, IST1, SKA2, JRKL, TRMT12, WDR27, ADSSL1, SHC4, YTHDF3, ZNF267, OR2AG2, PTAR1, SLX4, PRPF40A, RABL6, ANXA4, WDR5B, MAFG, TOPORS, KCNMB2, MFAP3L, PHACTR4, TRIQK, SUPT4H1, LTC4S, DDX47, FIS1, CKLF, FAM185A, RARB, IRF4, HOXA3 Regulons (53)R-2087, R-1556, R-2707, R-342, R-2610, R-2252, R-62, R-1904, R-1388, R-1266, R-2882, R-369, R-451, R-1677, R-1495, R-1591, R-771, R-2371, R-2535, R-1846, R-945, R-500, R-986, R-2995, R-2886, R-630, R-2738, R-2991, R-1735, R-1032, R-643, R-2069, R-1485, R-2179, R-2961, R-157, R-2336, R-2142, R-2358, R-1271, R-1489, R-1734, R-2090, R-1742, R-2070, R-3168, R-2704, R-994, R-2335, R-1786, R-539, R-2068, R-1929 |
| PLAG1 | down-regulates | R-1522 | 0.140759 | Pr-93 Genes (9)B3GNT5, PLEC, MME, ZNF700, SND1, VEPH1, ZNF480, ZHX1-C8orf76 Regulons (9)R-1522, R-564, R-13, R-1438, R-310, R-3131, R-826, R-2725, R-2630 |
| JUN | up-regulates | R-1185 | 0.14361 | Pr-118 Genes (18)ZNF169, CCDC121, LCORL, CUEDC1, ZBTB44, MIER1, ECI2, C4orf47, ZNF611, ERV3-1, HIGD1C, TOMM6, CSKMT, SMIM1, POU5F2, DPP3, EBLN2 Regulons (25)R-388, R-1185, R-2333, R-841, R-967, R-2625, R-125, R-1390, R-2192, R-1859, R-2750, R-1922, R-1788, R-842, R-1521, R-2694, R-131, R-1957, R-694, R-787, R-2413, R-2213, R-2689, R-1379, R-3146 |
| TRAF4 | up-regulates | R-3038 | -0.143949 | Pr-34 Genes (6)ACSF3, PPA1, CRIP2, TMEM216, MAGI2, TOGARAM1 Regulons (6)R-3038, R-1487, R-2881, R-1430, R-1835, R-2239 |
| NFIL3 | up-regulates | R-1686 | -0.145704 | Pr-25 Genes (9)RNPEP, RUFY1, ZNF664, TRNAU1AP, CLEC4G, SRC, HLA-F, RTL5 Regulons (9)R-974, R-1686, R-160, R-709, R-2312, R-2984, R-2341, R-2802, R-3062 |
| HOXA3 | down-regulates | R-222 | -0.14701 | Pr-87 Genes (18)LRRC37A3, PLEKHN1, AGRN, FAM221A, PNRC2, LONP1, HCAR1, NUP62CL, ZNF358, RUFY2, CXorf65, SDHD, FAM216A, C17orf67, FASTKD5, EID1 Regulons (20)R-222, R-1137, R-150, R-1228, R-2331, R-2713, R-3125, R-2052, R-664, R-2897, R-1544, R-2376, R-101, R-617, R-304, R-820, R-495, R-3021, R-1754, R-678 |
| FLI1 | down-regulates | R-782 | 0.152239 | Pr-137 Genes (22)KCNE3, SUGCT, SLC35A4, COX8A, PRR15, PFN4, FAM91A1, TMEM94, C14orf28, CMTR2, NQO1, FAM120C, PTPN1, SLC25A29, TMA16, MZT1, CSNK1E, KCTD7, CDK3, CHMP1B, COMMD3-BMI1 Regulons (23)R-2269, R-1302, R-186, R-1876, R-790, R-972, R-782, R-1579, R-1150, R-704, R-1950, R-1175, R-1457, R-1988, R-1345, R-713, R-3084, R-291, R-784, R-1348, R-2965, R-1533, R-1377 |
| RUNX3 | up-regulates | R-891 | -0.153019 | Pr-1 Genes (49)TOMM5, CTDNEP1, GAPT, UBE2O, CSTF3, DNAJC30, WSB2, PXMP2, MAMSTR, SIX5, ACER2, CHD9, RABEP2, DHFR2, RMI1, TMTC2, EDC3, PCED1B, PIPOX, ZNF154, ZNF816, MOB2, AP1S2, ACBD3, ZNF721, SPATA13, GDPGP1, ZNF438, TSSC4, H1FX, SYN3, RASA3, ZNF17, NUDT17, MITF, FAM122A, BLOC1S2, HLA-DQA1, LRP10, PELI1, TAF13, TMEM116, ZDHHC18, DENND1B, CFAP45, NDUFS3, TNF, PPP1R3E Regulons (54)R-2690, R-2360, R-579, R-2136, R-271, R-279, R-891, R-1826, R-1172, R-1395, R-2327, R-662, R-1685, R-2872, R-2264, R-2635, R-533, R-596, R-882, R-2045, R-1190, R-69, R-2474, R-1543, R-2600, R-1419, R-434, R-561, R-359, R-3074, R-1103, R-3169, R-2542, R-774, R-1630, R-3176, R-998, R-1864, R-1959, R-2074, R-1789, R-302, R-1062, R-483, R-2249, R-1841, R-1925, R-447, R-2808, R-874, R-1755, R-393, R-988, R-1109 |
| SPI1 | up-regulates | R-2610 | -0.164598 | Pr-117 Genes (51)LRRC25, MRPL48, CNTD1, EFCAB5, ZDHHC13, PPFIA3, TBL1XR1, IL17RA, POLR2L, KLHL28, SHARPIN, PHLDA2, IST1, SKA2, JRKL, TRMT12, WDR27, ADSSL1, SHC4, YTHDF3, ZNF267, OR2AG2, PTAR1, SLX4, PRPF40A, RABL6, ANXA4, WDR5B, MAFG, TOPORS, KCNMB2, MFAP3L, PHACTR4, TRIQK, SUPT4H1, LTC4S, DDX47, FIS1, CKLF, FAM185A, RARB, IRF4, HOXA3 Regulons (53)R-2087, R-1556, R-2707, R-342, R-2610, R-2252, R-62, R-1904, R-1388, R-1266, R-2882, R-369, R-451, R-1677, R-1495, R-1591, R-771, R-2371, R-2535, R-1846, R-945, R-500, R-986, R-2995, R-2886, R-630, R-2738, R-2991, R-1735, R-1032, R-643, R-2069, R-1485, R-2179, R-2961, R-157, R-2336, R-2142, R-2358, R-1271, R-1489, R-1734, R-2090, R-1742, R-2070, R-3168, R-2704, R-994, R-2335, R-1786, R-539, R-2068, R-1929 |
| ZSCAN16 | down-regulates | R-631 | -0.165596 | Pr-2 Genes (47)MSRA, PLEKHF2, NUPR1, IP6K1, TCP11L1, SPHK1, TYMS, FAM89B, WDR73, IRX3, ACAD9, CD151, KCNJ10, ARL6IP6, ODF3B, MPI, HYI, SPTY2D1, DAND5, ELMOD2, CDC42EP4, MAF1, SERTAD2, GLIPR1L2, LSMEM1, HIST3H2A, C5orf24, GINS3, RAD51B, MXRA7, BRICD5, RUVBL2, RBM12B, BRWD1, ANKRD37, TTC30B, SFI1, CTR9, CCDC167, PDXP Regulons (47)R-1855, R-2267, R-3037, R-486, R-2717, R-878, R-363, R-2104, R-631, R-3178, R-563, R-1911, R-436, R-183, R-2977, R-78, R-2479, R-2411, R-1825, R-49, R-272, R-390, R-1869, R-1831, R-2225, R-1586, R-775, R-535, R-1660, R-796, R-1574, R-1561, R-3126, R-2309, R-1717, R-2283, R-1341, R-2662, R-3007, R-2873, R-599, R-1189, R-2486, R-24, R-3064, R-570, R-288 |
| ELF1 | up-regulates | R-2981 | 0.167624 | Pr-138 Genes (9)SYNE3, SEC24C, WSCD1, RAP2B, ODF3L1, SEMA4A, SLC9A6, PATL2, C2orf15 Regulons (12)R-1666, R-2981, R-2567, R-1177, R-133, R-3011, R-472, R-11, R-169, R-2271, R-1668, R-1842 |
| ZBTB3 | down-regulates | R-1267 | 0.175091 | Pr-134 Genes (104)MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1 Regulons (119)R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272 |
| ATF4 | up-regulates | R-92 | 0.179335 | Pr-5 Genes (32)ZNF25, POLD4, CLK2, EPS8L2, PIDD1, JUN, AGTRAP, C2orf69, GRINA, PTPN11, PITPNB, DNAH14, C15orf41, KIF18B, DUSP28, CFAP126, ZFP62, MYO5A, FAM114A1, FAM118B, PIM3, ZNF627, TEX45, ITPRIPL1, MRPL53, TECPR1, RNPS1, CFAP44, ZNF726, EML6, LOC441155 Regulons (33)R-362, R-1924, R-1337, R-92, R-1207, R-3137, R-2527, R-2775, R-2562, R-1927, R-2749, R-2109, R-1198, R-1854, R-275, R-2883, R-3016, R-286, R-1350, R-2038, R-148, R-42, R-3198, R-2569, R-2282, R-581, R-590, R-2346, R-2265, R-2473, R-2377, R-2110, R-1385 |
| ENSG00000105991 | down-regulates | R-228 | -0.185488 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| ZBTB16 | up-regulates | R-589 | 0.185533 | Pr-125 Genes (16)RPS6KA3, GBA, HMGN4, CMTM4, TEAD1, BCAM, NIF3L1, MKL1, CR1, RING1, PVRIG, GET4, LOC102724159, PI4KA, SMIM20 Regulons (17)R-589, R-1538, R-54, R-2559, R-2953, R-223, R-1504, R-1914, R-3162, R-2359, R-1975, R-2741, R-2547, R-892, R-482, R-2476, R-1703 |
| E4F1 | up-regulates | R-3147 | -0.190868 | Pr-0 Genes (84)GPX2, BNIP3, METRNL, PUS1, SAMD12, CD163, SLC25A20, EFCAB13, EXOSC4, SAMD4B, CATSPERE, C14orf119, ARHGAP45, BBS12, EHMT1, SETD2, ZBTB20, RFX7, TSKU, SRPRA, SLC25A10, ASB7, UPP1, LIN9, CCR10, ZFP1, USP18, TNFAIP2, CDNF, SOCS1, METTL7A, PDE6G, SP1, P4HB, DRG1, CXorf38, MORF4L1, AIDA, WWOX, SAPCD2, PPP1CC, SPIN4, CXCR3, ZNF397, TPCN1, CMC1, GCNT1, FNBP1, RSBN1L, LOC100288637, TMPPE, ZC3H6, ZNF669, NANOS1, ALKBH2, JPT1, LIN54, HLA-DRB1, ZNF493, EPHB4, TRAPPC2B, SIAH1, ESRRG, TCF4, SERTAD1, ZNF398, ZNF257, ATG7, MPEG1, RPS4X, PNP, HMGN2, HIST2H2BF, COLQ, RPS29 Regulons (86)R-180, R-2076, R-2157, R-3164, R-3147, R-338, R-2156, R-2409, R-885, R-941, R-1192, R-556, R-3197, R-1572, R-999, R-636, R-902, R-2541, R-440, R-890, R-3175, R-767, R-1542, R-1336, R-2472, R-1698, R-2326, R-1906, R-269, R-772, R-647, R-3033, R-2100, R-2711, R-1394, R-3068, R-508, R-63, R-1916, R-1188, R-532, R-2135, R-997, R-1687, R-2951, R-1853, R-2220, R-577, R-585, R-2597, R-1021, R-3119, R-301, R-559, R-1560, R-175, R-2870, R-3015, R-66, R-595, R-3185, R-2905, R-433, R-290, R-381, R-2509, R-562, R-2798, R-2206, R-1418, R-60, R-3050, R-2073, R-611, R-2488, R-881, R-1095, R-2153, R-2553, R-2305, R-2656, R-1697, R-511, R-2185, R-1492, R-2555 |
| TCF4 | down-regulates | R-3004 | 0.195805 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| ATF4 | up-regulates | R-93 | 0.200122 | Pr-127 Genes (11)KCNA3, GIMAP5, ZSCAN16, PSAP, FAM109A, SMURF1, GPATCH3, RPL10A Regulons (12)R-93, R-1513, R-1824, R-1762, R-3039, R-2608, R-1268, R-85, R-2718, R-1784, R-1964, R-2203 |
| RUNX3 | up-regulates | R-894 | -0.20148 | Pr-14 Genes (17)TMEM70, TUBB6, PNMA1, CASKIN2, ANXA2R, MLF1, ARID3B, SLC17A8, FZD2, PLAG1, SLC8A1, SEMA4B, NOXA1, AKR1C3, MPV17L2 Regulons (18)R-1002, R-1429, R-1659, R-894, R-77, R-1832, R-1545, R-184, R-2284, R-2223, R-2075, R-2878, R-2606, R-1398, R-2952, R-1932, R-3170, R-2014 |
| THRA | up-regulates | R-62 | 0.204827 | Pr-117 Genes (51)LRRC25, MRPL48, CNTD1, EFCAB5, ZDHHC13, PPFIA3, TBL1XR1, IL17RA, POLR2L, KLHL28, SHARPIN, PHLDA2, IST1, SKA2, JRKL, TRMT12, WDR27, ADSSL1, SHC4, YTHDF3, ZNF267, OR2AG2, PTAR1, SLX4, PRPF40A, RABL6, ANXA4, WDR5B, MAFG, TOPORS, KCNMB2, MFAP3L, PHACTR4, TRIQK, SUPT4H1, LTC4S, DDX47, FIS1, CKLF, FAM185A, RARB, IRF4, HOXA3 Regulons (53)R-2087, R-1556, R-2707, R-342, R-2610, R-2252, R-62, R-1904, R-1388, R-1266, R-2882, R-369, R-451, R-1677, R-1495, R-1591, R-771, R-2371, R-2535, R-1846, R-945, R-500, R-986, R-2995, R-2886, R-630, R-2738, R-2991, R-1735, R-1032, R-643, R-2069, R-1485, R-2179, R-2961, R-157, R-2336, R-2142, R-2358, R-1271, R-1489, R-1734, R-2090, R-1742, R-2070, R-3168, R-2704, R-994, R-2335, R-1786, R-539, R-2068, R-1929 |
| HSF2 | up-regulates | R-3159 | -0.213586 | Pr-85 Genes (18)A2M, ANAPC2, NIM1K, ZFAND2A, GCC1, ERCC6L2, UBE2E2, MTA1, TOB2, SNAI3, RINL, SMIM15, SULT1C2, SMG5, SYS1, CDPF1, SLC12A8, ITGB3 Regulons (21)R-2966, R-484, R-3159, R-597, R-661, R-1688, R-1272, R-2328, R-615, R-2366, R-2374, R-2647, R-360, R-977, R-3017, R-1311, R-622, R-3187, R-2071, R-3002, R-2492 |
| RARA | up-regulates | R-161 | -0.215419 | Pr-112 Genes (5)CD19, COMMD6, MRPL21, IPP, FAM228B Regulons (10)R-161, R-1838, R-3036, R-1491, R-2275, R-835, R-676, R-1746, R-592, R-1218 |
| NF1 | up-regulates | R-127 | -0.22305 | Pr-18 Genes (11)RPRM, FRAT2, SCFD2, PARPBP, ADAT2, INCA1, CASP4, DDRGK1, DDR1 Regulons (15)R-127, R-1406, R-1883, R-89, R-221, R-1440, R-604, R-2385, R-2515, R-1076, R-165, R-2899, R-2246, R-2731, R-1671 |
| NFIL3 | up-regulates | R-1685 | 0.22459 | Pr-1 Genes (49)TOMM5, CTDNEP1, GAPT, UBE2O, CSTF3, DNAJC30, WSB2, PXMP2, MAMSTR, SIX5, ACER2, CHD9, RABEP2, DHFR2, RMI1, TMTC2, EDC3, PCED1B, PIPOX, ZNF154, ZNF816, MOB2, AP1S2, ACBD3, ZNF721, SPATA13, GDPGP1, ZNF438, TSSC4, H1FX, SYN3, RASA3, ZNF17, NUDT17, MITF, FAM122A, BLOC1S2, HLA-DQA1, LRP10, PELI1, TAF13, TMEM116, ZDHHC18, DENND1B, CFAP45, NDUFS3, TNF, PPP1R3E Regulons (54)R-2690, R-2360, R-579, R-2136, R-271, R-279, R-891, R-1826, R-1172, R-1395, R-2327, R-662, R-1685, R-2872, R-2264, R-2635, R-533, R-596, R-882, R-2045, R-1190, R-69, R-2474, R-1543, R-2600, R-1419, R-434, R-561, R-359, R-3074, R-1103, R-3169, R-2542, R-774, R-1630, R-3176, R-998, R-1864, R-1959, R-2074, R-1789, R-302, R-1062, R-483, R-2249, R-1841, R-1925, R-447, R-2808, R-874, R-1755, R-393, R-988, R-1109 |
| ETS2 | up-regulates | R-1904 | 0.237053 | Pr-117 Genes (51)LRRC25, MRPL48, CNTD1, EFCAB5, ZDHHC13, PPFIA3, TBL1XR1, IL17RA, POLR2L, KLHL28, SHARPIN, PHLDA2, IST1, SKA2, JRKL, TRMT12, WDR27, ADSSL1, SHC4, YTHDF3, ZNF267, OR2AG2, PTAR1, SLX4, PRPF40A, RABL6, ANXA4, WDR5B, MAFG, TOPORS, KCNMB2, MFAP3L, PHACTR4, TRIQK, SUPT4H1, LTC4S, DDX47, FIS1, CKLF, FAM185A, RARB, IRF4, HOXA3 Regulons (53)R-2087, R-1556, R-2707, R-342, R-2610, R-2252, R-62, R-1904, R-1388, R-1266, R-2882, R-369, R-451, R-1677, R-1495, R-1591, R-771, R-2371, R-2535, R-1846, R-945, R-500, R-986, R-2995, R-2886, R-630, R-2738, R-2991, R-1735, R-1032, R-643, R-2069, R-1485, R-2179, R-2961, R-157, R-2336, R-2142, R-2358, R-1271, R-1489, R-1734, R-2090, R-1742, R-2070, R-3168, R-2704, R-994, R-2335, R-1786, R-539, R-2068, R-1929 |
| ETV5 | up-regulates | R-338 | -0.237093 | Pr-0 Genes (84)GPX2, BNIP3, METRNL, PUS1, SAMD12, CD163, SLC25A20, EFCAB13, EXOSC4, SAMD4B, CATSPERE, C14orf119, ARHGAP45, BBS12, EHMT1, SETD2, ZBTB20, RFX7, TSKU, SRPRA, SLC25A10, ASB7, UPP1, LIN9, CCR10, ZFP1, USP18, TNFAIP2, CDNF, SOCS1, METTL7A, PDE6G, SP1, P4HB, DRG1, CXorf38, MORF4L1, AIDA, WWOX, SAPCD2, PPP1CC, SPIN4, CXCR3, ZNF397, TPCN1, CMC1, GCNT1, FNBP1, RSBN1L, LOC100288637, TMPPE, ZC3H6, ZNF669, NANOS1, ALKBH2, JPT1, LIN54, HLA-DRB1, ZNF493, EPHB4, TRAPPC2B, SIAH1, ESRRG, TCF4, SERTAD1, ZNF398, ZNF257, ATG7, MPEG1, RPS4X, PNP, HMGN2, HIST2H2BF, COLQ, RPS29 Regulons (86)R-180, R-2076, R-2157, R-3164, R-3147, R-338, R-2156, R-2409, R-885, R-941, R-1192, R-556, R-3197, R-1572, R-999, R-636, R-902, R-2541, R-440, R-890, R-3175, R-767, R-1542, R-1336, R-2472, R-1698, R-2326, R-1906, R-269, R-772, R-647, R-3033, R-2100, R-2711, R-1394, R-3068, R-508, R-63, R-1916, R-1188, R-532, R-2135, R-997, R-1687, R-2951, R-1853, R-2220, R-577, R-585, R-2597, R-1021, R-3119, R-301, R-559, R-1560, R-175, R-2870, R-3015, R-66, R-595, R-3185, R-2905, R-433, R-290, R-381, R-2509, R-562, R-2798, R-2206, R-1418, R-60, R-3050, R-2073, R-611, R-2488, R-881, R-1095, R-2153, R-2553, R-2305, R-2656, R-1697, R-511, R-2185, R-1492, R-2555 |
| JUN | up-regulates | R-1187 | -0.237713 | Pr-12 Genes (14)CDK5R1, C18orf32, ARL6IP4, NELFA, INTS5, TCEAL9, ZNF431, ZNF81, FAM49A, ARMH1, C2CD4A, GIGYF2, SPIRE2, TMA7 Regulons (17)R-776, R-1187, R-3181, R-555, R-2154, R-2189, R-1434, R-189, R-3127, R-2242, R-1403, R-281, R-2291, R-2193, R-1033, R-1861, R-2245 |
| NR2C2 | down-regulates | R-1388 | -0.247005 | Pr-117 Genes (51)LRRC25, MRPL48, CNTD1, EFCAB5, ZDHHC13, PPFIA3, TBL1XR1, IL17RA, POLR2L, KLHL28, SHARPIN, PHLDA2, IST1, SKA2, JRKL, TRMT12, WDR27, ADSSL1, SHC4, YTHDF3, ZNF267, OR2AG2, PTAR1, SLX4, PRPF40A, RABL6, ANXA4, WDR5B, MAFG, TOPORS, KCNMB2, MFAP3L, PHACTR4, TRIQK, SUPT4H1, LTC4S, DDX47, FIS1, CKLF, FAM185A, RARB, IRF4, HOXA3 Regulons (53)R-2087, R-1556, R-2707, R-342, R-2610, R-2252, R-62, R-1904, R-1388, R-1266, R-2882, R-369, R-451, R-1677, R-1495, R-1591, R-771, R-2371, R-2535, R-1846, R-945, R-500, R-986, R-2995, R-2886, R-630, R-2738, R-2991, R-1735, R-1032, R-643, R-2069, R-1485, R-2179, R-2961, R-157, R-2336, R-2142, R-2358, R-1271, R-1489, R-1734, R-2090, R-1742, R-2070, R-3168, R-2704, R-994, R-2335, R-1786, R-539, R-2068, R-1929 |
| SOX4 | down-regulates | R-2187 | 0.253475 | Pr-97 |
| POU2F1 | up-regulates | R-77 | -0.259838 | Pr-14 Genes (17)TMEM70, TUBB6, PNMA1, CASKIN2, ANXA2R, MLF1, ARID3B, SLC17A8, FZD2, PLAG1, SLC8A1, SEMA4B, NOXA1, AKR1C3, MPV17L2 Regulons (18)R-1002, R-1429, R-1659, R-894, R-77, R-1832, R-1545, R-184, R-2284, R-2223, R-2075, R-2878, R-2606, R-1398, R-2952, R-1932, R-3170, R-2014 |
| HLX | up-regulates | R-2764 | 0.260576 | Pr-134 Genes (104)MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1 Regulons (119)R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272 |
| TP53 | down-regulates | R-372 | -0.261151 | Pr-133 Genes (6)UCP3, GJD4, ACOT4, HNRNPA0, ZCWPW2 Regulons (7)R-3071, R-1940, R-2231, R-372, R-2200, R-2945, R-2989 |
| IRF1 | up-regulates | R-183 | -0.261893 | Pr-2 Genes (47)MSRA, PLEKHF2, NUPR1, IP6K1, TCP11L1, SPHK1, TYMS, FAM89B, WDR73, IRX3, ACAD9, CD151, KCNJ10, ARL6IP6, ODF3B, MPI, HYI, SPTY2D1, DAND5, ELMOD2, CDC42EP4, MAF1, SERTAD2, GLIPR1L2, LSMEM1, HIST3H2A, C5orf24, GINS3, RAD51B, MXRA7, BRICD5, RUVBL2, RBM12B, BRWD1, ANKRD37, TTC30B, SFI1, CTR9, CCDC167, PDXP Regulons (47)R-1855, R-2267, R-3037, R-486, R-2717, R-878, R-363, R-2104, R-631, R-3178, R-563, R-1911, R-436, R-183, R-2977, R-78, R-2479, R-2411, R-1825, R-49, R-272, R-390, R-1869, R-1831, R-2225, R-1586, R-775, R-535, R-1660, R-796, R-1574, R-1561, R-3126, R-2309, R-1717, R-2283, R-1341, R-2662, R-3007, R-2873, R-599, R-1189, R-2486, R-24, R-3064, R-570, R-288 |
| MAFB | up-regulates | R-1733 | -0.268219 | Pr-29 Genes (9)P2RY2, SAMD9L, TMEM187, TRAK1, ANKRD45, PTP4A2, ZNF565, C17orf51 Regulons (9)R-1401, R-1870, R-1733, R-80, R-2197, R-993, R-1308, R-2683, R-548 |
| ELF1 | up-regulates | R-2977 | -0.272173 | Pr-2 Genes (47)MSRA, PLEKHF2, NUPR1, IP6K1, TCP11L1, SPHK1, TYMS, FAM89B, WDR73, IRX3, ACAD9, CD151, KCNJ10, ARL6IP6, ODF3B, MPI, HYI, SPTY2D1, DAND5, ELMOD2, CDC42EP4, MAF1, SERTAD2, GLIPR1L2, LSMEM1, HIST3H2A, C5orf24, GINS3, RAD51B, MXRA7, BRICD5, RUVBL2, RBM12B, BRWD1, ANKRD37, TTC30B, SFI1, CTR9, CCDC167, PDXP Regulons (47)R-1855, R-2267, R-3037, R-486, R-2717, R-878, R-363, R-2104, R-631, R-3178, R-563, R-1911, R-436, R-183, R-2977, R-78, R-2479, R-2411, R-1825, R-49, R-272, R-390, R-1869, R-1831, R-2225, R-1586, R-775, R-535, R-1660, R-796, R-1574, R-1561, R-3126, R-2309, R-1717, R-2283, R-1341, R-2662, R-3007, R-2873, R-599, R-1189, R-2486, R-24, R-3064, R-570, R-288 |
| POU2F1 | up-regulates | R-78 | -0.272418 | Pr-2 Genes (47)MSRA, PLEKHF2, NUPR1, IP6K1, TCP11L1, SPHK1, TYMS, FAM89B, WDR73, IRX3, ACAD9, CD151, KCNJ10, ARL6IP6, ODF3B, MPI, HYI, SPTY2D1, DAND5, ELMOD2, CDC42EP4, MAF1, SERTAD2, GLIPR1L2, LSMEM1, HIST3H2A, C5orf24, GINS3, RAD51B, MXRA7, BRICD5, RUVBL2, RBM12B, BRWD1, ANKRD37, TTC30B, SFI1, CTR9, CCDC167, PDXP Regulons (47)R-1855, R-2267, R-3037, R-486, R-2717, R-878, R-363, R-2104, R-631, R-3178, R-563, R-1911, R-436, R-183, R-2977, R-78, R-2479, R-2411, R-1825, R-49, R-272, R-390, R-1869, R-1831, R-2225, R-1586, R-775, R-535, R-1660, R-796, R-1574, R-1561, R-3126, R-2309, R-1717, R-2283, R-1341, R-2662, R-3007, R-2873, R-599, R-1189, R-2486, R-24, R-3064, R-570, R-288 |
| EGR1 | down-regulates | R-2895 | -0.27249 | Pr-6 Genes (31)SART1, C11orf68, TALDO1, GPR150, ZNF543, COX14, ZNF571, KCTD2, PRKAG1, CSF1R, VMO1, SMDT1, SF3A3, TTC32, XPOT, KRBA2, MED12, APOBR, SDR42E1, FMNL1, ZBTB37, L3MBTL1, TRABD2A, CD55, ZNF34, DCHS2, CRIP1, NDUFA7 Regulons (31)R-46, R-2648, R-3177, R-869, R-2895, R-64, R-940, R-1917, R-3120, R-435, R-697, R-2958, R-886, R-1865, R-2783, R-1396, R-1420, R-1057, R-2768, R-2047, R-2528, R-2603, R-557, R-178, R-2874, R-70, R-2298, R-2329, R-2561, R-651, R-1845 |
| FOXJ2 | up-regulates | R-1425 | 0.273367 | Pr-124 Genes (20)MYPOP, DMAP1, PER1, C1S, DENND5A, TSPYL2, KNTC1, TMEM105, LRCH3, ZBTB6, CFAP73, LILRB4, TNFRSF18, LITAF, ZNF665, IPO7, KMT2B Regulons (20)R-1400, R-1425, R-1962, R-1828, R-991, R-1083, R-1577, R-72, R-2158, R-3069, R-2814, R-1149, R-1631, R-182, R-1340, R-3034, R-3139, R-39, R-199, R-593 |
| HBP1 | up-regulates | R-1832 | 0.278908 | Pr-14 Genes (17)TMEM70, TUBB6, PNMA1, CASKIN2, ANXA2R, MLF1, ARID3B, SLC17A8, FZD2, PLAG1, SLC8A1, SEMA4B, NOXA1, AKR1C3, MPV17L2 Regulons (18)R-1002, R-1429, R-1659, R-894, R-77, R-1832, R-1545, R-184, R-2284, R-2223, R-2075, R-2878, R-2606, R-1398, R-2952, R-1932, R-3170, R-2014 |
| IRF1 | up-regulates | R-191 | 0.280655 | Pr-16 Genes (20)NR2C2, LOC653513, C11orf54, ZNRF3, NSMCE3, LRRC70, TAF9B, B3GLCT, ZNF775, PPTC7, TRIM33, SIPA1L1, ZNF460, ZNF790, ZKSCAN8, CEP290, CIPC, GIMAP1, LILRA6, CHMP4A Regulons (20)R-383, R-191, R-50, R-872, R-1431, R-1919, R-1532, R-1546, R-2884, R-84, R-2290, R-666, R-1935, R-3128, R-1871, R-2949, R-2227, R-156, R-1279, R-2522 |
| FOXJ3 | up-regulates | R-2876 | -0.290335 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| ELF4 | up-regulates | R-2333 | 0.29758 | Pr-118 Genes (18)ZNF169, CCDC121, LCORL, CUEDC1, ZBTB44, MIER1, ECI2, C4orf47, ZNF611, ERV3-1, HIGD1C, TOMM6, CSKMT, SMIM1, POU5F2, DPP3, EBLN2 Regulons (25)R-388, R-1185, R-2333, R-841, R-967, R-2625, R-125, R-1390, R-2192, R-1859, R-2750, R-1922, R-1788, R-842, R-1521, R-2694, R-131, R-1957, R-694, R-787, R-2413, R-2213, R-2689, R-1379, R-3146 |
| ATF1 | up-regulates | R-564 | 0.297759 | Pr-93 Genes (9)B3GNT5, PLEC, MME, ZNF700, SND1, VEPH1, ZNF480, ZHX1-C8orf76 Regulons (9)R-1522, R-564, R-13, R-1438, R-310, R-3131, R-826, R-2725, R-2630 |
| PEBP1 | up-regulates | R-1756 | -0.29837 | Pr-58 Genes (28)ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28)R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148 |
| MAFG | up-regulates | R-1490 | -0.300169 | Pr-58 Genes (28)ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28)R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148 |
| ELF1 | up-regulates | R-2979 | -0.300753 | Pr-64 Genes (6)NT5DC1, APOO, ANKFY1, FANCM, RAB42, ZNF425 Regulons (8)R-2979, R-2609, R-7, R-1073, R-1404, R-1, R-887, R-1856 |
| BHLHE40 | up-regulates | R-940 | -0.302306 | Pr-6 Genes (31)SART1, C11orf68, TALDO1, GPR150, ZNF543, COX14, ZNF571, KCTD2, PRKAG1, CSF1R, VMO1, SMDT1, SF3A3, TTC32, XPOT, KRBA2, MED12, APOBR, SDR42E1, FMNL1, ZBTB37, L3MBTL1, TRABD2A, CD55, ZNF34, DCHS2, CRIP1, NDUFA7 Regulons (31)R-46, R-2648, R-3177, R-869, R-2895, R-64, R-940, R-1917, R-3120, R-435, R-697, R-2958, R-886, R-1865, R-2783, R-1396, R-1420, R-1057, R-2768, R-2047, R-2528, R-2603, R-557, R-178, R-2874, R-70, R-2298, R-2329, R-2561, R-651, R-1845 |
| POU2F1 | up-regulates | R-83 | -0.310208 | Pr-41 Genes (9)CABP4, SFN, YES1, CSTF2T, KLHL11, DEXI, SOCS3, HIST2H2BE, ZNF248 Regulons (10)R-1382, R-479, R-1436, R-1086, R-83, R-971, R-1757, R-2378, R-3091, R-677 |
| SF1 | up-regulates | R-1907 | -0.317014 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| GABPB1 | up-regulates | R-1954 | -0.317917 | Pr-39 Genes (11)PAAF1, KDF1, CD28, MAF, TBK1, PGP, FCAR, APOL6, SIGLEC14, MTRNR2L2 Regulons (17)R-889, R-2846, R-1954, R-558, R-2141, R-1857, R-708, R-378, R-1343, R-2900, R-1704, R-2347, R-2988, R-2552, R-1245, R-474, R-2797 |
| TFE3 | up-regulates | R-558 | -0.31956 | Pr-39 Genes (11)PAAF1, KDF1, CD28, MAF, TBK1, PGP, FCAR, APOL6, SIGLEC14, MTRNR2L2 Regulons (17)R-889, R-2846, R-1954, R-558, R-2141, R-1857, R-708, R-378, R-1343, R-2900, R-1704, R-2347, R-2988, R-2552, R-1245, R-474, R-2797 |
| ZFX | up-regulates | R-1920 | -0.319605 | Pr-129 Genes (12)DALRD3, CTNNBIP1, FAHD1, ZBTB2, SLC2A4, UBA7, KLHDC8B, BCDIN3D, FAM111B, MAN1A2, HYLS1, INF2 Regulons (12)R-356, R-1920, R-2758, R-2274, R-507, R-1886, R-1777, R-1479, R-1180, R-2321, R-756, R-1179 |
| ZBTB3 | down-regulates | R-1273 | -0.320737 | Pr-111 Genes (12)PARP10, ZHX2, DNHD1, MRPL54, BRI3BP, TET3, DNAJB13, CDC42SE1, RPL23A, WDHD1 Regulons (12)R-1273, R-1009, R-2956, R-2337, R-983, R-2356, R-711, R-299, R-1708, R-3092, R-2721, R-1074 |
| ZNF281 | up-regulates | R-2490 | 0.3247 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| EWSR1 | up-regulates | R-2562 | 0.325625 | Pr-5 Genes (32)ZNF25, POLD4, CLK2, EPS8L2, PIDD1, JUN, AGTRAP, C2orf69, GRINA, PTPN11, PITPNB, DNAH14, C15orf41, KIF18B, DUSP28, CFAP126, ZFP62, MYO5A, FAM114A1, FAM118B, PIM3, ZNF627, TEX45, ITPRIPL1, MRPL53, TECPR1, RNPS1, CFAP44, ZNF726, EML6, LOC441155 Regulons (33)R-362, R-1924, R-1337, R-92, R-1207, R-3137, R-2527, R-2775, R-2562, R-1927, R-2749, R-2109, R-1198, R-1854, R-275, R-2883, R-3016, R-286, R-1350, R-2038, R-148, R-42, R-3198, R-2569, R-2282, R-581, R-590, R-2346, R-2265, R-2473, R-2377, R-2110, R-1385 |
| ENSG00000054598 | up-regulates | R-1009 | 0.330498 | Pr-111 Genes (12)PARP10, ZHX2, DNHD1, MRPL54, BRI3BP, TET3, DNAJB13, CDC42SE1, RPL23A, WDHD1 Regulons (12)R-1273, R-1009, R-2956, R-2337, R-983, R-2356, R-711, R-299, R-1708, R-3092, R-2721, R-1074 |
| RARA | up-regulates | R-160 | -0.331894 | Pr-25 Genes (9)RNPEP, RUFY1, ZNF664, TRNAU1AP, CLEC4G, SRC, HLA-F, RTL5 Regulons (9)R-974, R-1686, R-160, R-709, R-2312, R-2984, R-2341, R-2802, R-3062 |
| ZNF281 | up-regulates | R-2479 | -0.333368 | Pr-2 Genes (47)MSRA, PLEKHF2, NUPR1, IP6K1, TCP11L1, SPHK1, TYMS, FAM89B, WDR73, IRX3, ACAD9, CD151, KCNJ10, ARL6IP6, ODF3B, MPI, HYI, SPTY2D1, DAND5, ELMOD2, CDC42EP4, MAF1, SERTAD2, GLIPR1L2, LSMEM1, HIST3H2A, C5orf24, GINS3, RAD51B, MXRA7, BRICD5, RUVBL2, RBM12B, BRWD1, ANKRD37, TTC30B, SFI1, CTR9, CCDC167, PDXP Regulons (47)R-1855, R-2267, R-3037, R-486, R-2717, R-878, R-363, R-2104, R-631, R-3178, R-563, R-1911, R-436, R-183, R-2977, R-78, R-2479, R-2411, R-1825, R-49, R-272, R-390, R-1869, R-1831, R-2225, R-1586, R-775, R-535, R-1660, R-796, R-1574, R-1561, R-3126, R-2309, R-1717, R-2283, R-1341, R-2662, R-3007, R-2873, R-599, R-1189, R-2486, R-24, R-3064, R-570, R-288 |
| TGIF1 | up-regulates | R-2503 | 0.333611 | Pr-120 Genes (9)ANKLE2, TMEM52, YOD1, ZNF443, CDCA2, SIVA1, PSMD13, CHAMP1 Regulons (9)R-2299, R-2503, R-2342, R-546, R-2201, R-1346, R-1651, R-792, R-2963 |
| TFEB | up-regulates | R-885 | -0.336909 | Pr-0 Genes (84)GPX2, BNIP3, METRNL, PUS1, SAMD12, CD163, SLC25A20, EFCAB13, EXOSC4, SAMD4B, CATSPERE, C14orf119, ARHGAP45, BBS12, EHMT1, SETD2, ZBTB20, RFX7, TSKU, SRPRA, SLC25A10, ASB7, UPP1, LIN9, CCR10, ZFP1, USP18, TNFAIP2, CDNF, SOCS1, METTL7A, PDE6G, SP1, P4HB, DRG1, CXorf38, MORF4L1, AIDA, WWOX, SAPCD2, PPP1CC, SPIN4, CXCR3, ZNF397, TPCN1, CMC1, GCNT1, FNBP1, RSBN1L, LOC100288637, TMPPE, ZC3H6, ZNF669, NANOS1, ALKBH2, JPT1, LIN54, HLA-DRB1, ZNF493, EPHB4, TRAPPC2B, SIAH1, ESRRG, TCF4, SERTAD1, ZNF398, ZNF257, ATG7, MPEG1, RPS4X, PNP, HMGN2, HIST2H2BF, COLQ, RPS29 Regulons (86)R-180, R-2076, R-2157, R-3164, R-3147, R-338, R-2156, R-2409, R-885, R-941, R-1192, R-556, R-3197, R-1572, R-999, R-636, R-902, R-2541, R-440, R-890, R-3175, R-767, R-1542, R-1336, R-2472, R-1698, R-2326, R-1906, R-269, R-772, R-647, R-3033, R-2100, R-2711, R-1394, R-3068, R-508, R-63, R-1916, R-1188, R-532, R-2135, R-997, R-1687, R-2951, R-1853, R-2220, R-577, R-585, R-2597, R-1021, R-3119, R-301, R-559, R-1560, R-175, R-2870, R-3015, R-66, R-595, R-3185, R-2905, R-433, R-290, R-381, R-2509, R-562, R-2798, R-2206, R-1418, R-60, R-3050, R-2073, R-611, R-2488, R-881, R-1095, R-2153, R-2553, R-2305, R-2656, R-1697, R-511, R-2185, R-1492, R-2555 |
| CEBPB | up-regulates | R-1768 | -0.337185 | Pr-109 Genes (12)MAN1B1, APOLD1, GEMIN4, GPR135, HIST2H2AB, MBP, ZXDB, FAM19A5, PPT2, DBNDD2, PGAM5, ETV6 Regulons (15)R-2714, R-1768, R-130, R-1972, R-2652, R-10, R-1079, R-1946, R-2505, R-2405, R-1478, R-1654, R-830, R-1773, R-170 |
| BHLHE40 | up-regulates | R-941 | 0.337997 | Pr-0 Genes (84)GPX2, BNIP3, METRNL, PUS1, SAMD12, CD163, SLC25A20, EFCAB13, EXOSC4, SAMD4B, CATSPERE, C14orf119, ARHGAP45, BBS12, EHMT1, SETD2, ZBTB20, RFX7, TSKU, SRPRA, SLC25A10, ASB7, UPP1, LIN9, CCR10, ZFP1, USP18, TNFAIP2, CDNF, SOCS1, METTL7A, PDE6G, SP1, P4HB, DRG1, CXorf38, MORF4L1, AIDA, WWOX, SAPCD2, PPP1CC, SPIN4, CXCR3, ZNF397, TPCN1, CMC1, GCNT1, FNBP1, RSBN1L, LOC100288637, TMPPE, ZC3H6, ZNF669, NANOS1, ALKBH2, JPT1, LIN54, HLA-DRB1, ZNF493, EPHB4, TRAPPC2B, SIAH1, ESRRG, TCF4, SERTAD1, ZNF398, ZNF257, ATG7, MPEG1, RPS4X, PNP, HMGN2, HIST2H2BF, COLQ, RPS29 Regulons (86)R-180, R-2076, R-2157, R-3164, R-3147, R-338, R-2156, R-2409, R-885, R-941, R-1192, R-556, R-3197, R-1572, R-999, R-636, R-902, R-2541, R-440, R-890, R-3175, R-767, R-1542, R-1336, R-2472, R-1698, R-2326, R-1906, R-269, R-772, R-647, R-3033, R-2100, R-2711, R-1394, R-3068, R-508, R-63, R-1916, R-1188, R-532, R-2135, R-997, R-1687, R-2951, R-1853, R-2220, R-577, R-585, R-2597, R-1021, R-3119, R-301, R-559, R-1560, R-175, R-2870, R-3015, R-66, R-595, R-3185, R-2905, R-433, R-290, R-381, R-2509, R-562, R-2798, R-2206, R-1418, R-60, R-3050, R-2073, R-611, R-2488, R-881, R-1095, R-2153, R-2553, R-2305, R-2656, R-1697, R-511, R-2185, R-1492, R-2555 |
| XBP1 | down-regulates | R-3059 | 0.341163 | Pr-35 Genes (10)ZBTB7A, TMEM107, BHLHA15, GLTPD2, ZNF395, MAFB, SMIM13, AKAP2, FOX3A Regulons (20)R-2747, R-3059, R-336, R-2624, R-1948, R-14, R-277, R-2826, R-1570, R-1094, R-1244, R-2621, R-1232, R-1506, R-3019, R-493, R-1945, R-2691, R-1963, R-2244 |
| PARP1 | down-regulates | R-2637 | 0.341341 | Pr-24 Genes (7)CTC1, CITED4, UBQLN2, NMB, CHML, PPP1CB Regulons (8)R-2637, R-700, R-91, R-768, R-1882, R-3123, R-1833, R-2533 |
| TRAF4 | up-regulates | R-3042 | -0.342468 | Pr-122 Genes (6)NSUN3, EIF3K, ANXA2, LCK, TLR7, PAM16 Regulons (21)R-2218, R-3042, R-2501, R-2962, R-1078, R-1900, R-1098, R-2812, R-2168, R-1712, R-27, R-2760, R-1892, R-680, R-2370, R-1248, R-1693, R-2525, R-2673, R-1772, R-519 |
| ENSG00000177374 | down-regulates | R-2364 | 0.342897 | Pr-139 Genes (11)MRFAP1, PRKRA, BAZ1A, FAM72D, LHX4-AS1, ZNF709, TMEM35B, ATXN7L3B, NFIA Regulons (11)R-2364, R-2807, R-3003, R-3009, R-3093, R-2967, R-1776, R-2212, R-397, R-3022, R-1524 |
| HMGA1 | down-regulates | R-817 | -0.342996 | Pr-58 Genes (28)ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28)R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148 |
| MAFB | up-regulates | R-1748 | -0.346189 | Pr-134 Genes (104)MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1 Regulons (119)R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272 |
| HBP1 | up-regulates | R-1828 | 0.348637 | Pr-124 Genes (20)MYPOP, DMAP1, PER1, C1S, DENND5A, TSPYL2, KNTC1, TMEM105, LRCH3, ZBTB6, CFAP73, LILRB4, TNFRSF18, LITAF, ZNF665, IPO7, KMT2B Regulons (20)R-1400, R-1425, R-1962, R-1828, R-991, R-1083, R-1577, R-72, R-2158, R-3069, R-2814, R-1149, R-1631, R-182, R-1340, R-3034, R-3139, R-39, R-199, R-593 |
| PARP1 | down-regulates | R-2635 | -0.349554 | Pr-1 Genes (49)TOMM5, CTDNEP1, GAPT, UBE2O, CSTF3, DNAJC30, WSB2, PXMP2, MAMSTR, SIX5, ACER2, CHD9, RABEP2, DHFR2, RMI1, TMTC2, EDC3, PCED1B, PIPOX, ZNF154, ZNF816, MOB2, AP1S2, ACBD3, ZNF721, SPATA13, GDPGP1, ZNF438, TSSC4, H1FX, SYN3, RASA3, ZNF17, NUDT17, MITF, FAM122A, BLOC1S2, HLA-DQA1, LRP10, PELI1, TAF13, TMEM116, ZDHHC18, DENND1B, CFAP45, NDUFS3, TNF, PPP1R3E Regulons (54)R-2690, R-2360, R-579, R-2136, R-271, R-279, R-891, R-1826, R-1172, R-1395, R-2327, R-662, R-1685, R-2872, R-2264, R-2635, R-533, R-596, R-882, R-2045, R-1190, R-69, R-2474, R-1543, R-2600, R-1419, R-434, R-561, R-359, R-3074, R-1103, R-3169, R-2542, R-774, R-1630, R-3176, R-998, R-1864, R-1959, R-2074, R-1789, R-302, R-1062, R-483, R-2249, R-1841, R-1925, R-447, R-2808, R-874, R-1755, R-393, R-988, R-1109 |
| ENSG00000162367 | up-regulates | R-1705 | -0.363284 | Pr-134 Genes (104)MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1 Regulons (119)R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272 |
| ZFX | up-regulates | R-1927 | -0.36742 | Pr-5 Genes (32)ZNF25, POLD4, CLK2, EPS8L2, PIDD1, JUN, AGTRAP, C2orf69, GRINA, PTPN11, PITPNB, DNAH14, C15orf41, KIF18B, DUSP28, CFAP126, ZFP62, MYO5A, FAM114A1, FAM118B, PIM3, ZNF627, TEX45, ITPRIPL1, MRPL53, TECPR1, RNPS1, CFAP44, ZNF726, EML6, LOC441155 Regulons (33)R-362, R-1924, R-1337, R-92, R-1207, R-3137, R-2527, R-2775, R-2562, R-1927, R-2749, R-2109, R-1198, R-1854, R-275, R-2883, R-3016, R-286, R-1350, R-2038, R-148, R-42, R-3198, R-2569, R-2282, R-581, R-590, R-2346, R-2265, R-2473, R-2377, R-2110, R-1385 |
| RFX1 | up-regulates | R-2567 | 0.369595 | Pr-138 Genes (9)SYNE3, SEC24C, WSCD1, RAP2B, ODF3L1, SEMA4A, SLC9A6, PATL2, C2orf15 Regulons (12)R-1666, R-2981, R-2567, R-1177, R-133, R-3011, R-472, R-11, R-169, R-2271, R-1668, R-1842 |
| IRF8 | up-regulates | R-2634 | 0.369682 | Pr-134 Genes (104)MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1 Regulons (119)R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272 |
| ENSG00000176887 | up-regulates | R-1893 | 0.370377 | Pr-128 Genes (4)C10orf67, CLK3, PSTK Regulons (11)R-1200, R-1893, R-2641, R-1739, R-1183, R-1246, R-3081, R-225, R-1880, R-1475, R-90 |
| HBP1 | up-regulates | R-1839 | 0.37241 | Pr-23 Genes (14)LRRTM4, LMNB2, B3GNT8, HLA-DQB1, TIGD5, FIZ1, C3orf58, CREB3L2, ALG12, BTN3A2, ENTPD5, TBC1D9B Regulons (14)R-2081, R-1884, R-1719, R-1839, R-2182, R-1274, R-2732, R-2344, R-477, R-3190, R-2889, R-309, R-371, R-444 |
| DBP | down-regulates | R-2956 | -0.373848 | Pr-111 Genes (12)PARP10, ZHX2, DNHD1, MRPL54, BRI3BP, TET3, DNAJB13, CDC42SE1, RPL23A, WDHD1 Regulons (12)R-1273, R-1009, R-2956, R-2337, R-983, R-2356, R-711, R-299, R-1708, R-3092, R-2721, R-1074 |
| PAX6 | down-regulates | R-1545 | -0.374773 | Pr-14 Genes (17)TMEM70, TUBB6, PNMA1, CASKIN2, ANXA2R, MLF1, ARID3B, SLC17A8, FZD2, PLAG1, SLC8A1, SEMA4B, NOXA1, AKR1C3, MPV17L2 Regulons (18)R-1002, R-1429, R-1659, R-894, R-77, R-1832, R-1545, R-184, R-2284, R-2223, R-2075, R-2878, R-2606, R-1398, R-2952, R-1932, R-3170, R-2014 |
| HMBOX1 | up-regulates | R-2382 | 0.378178 | Pr-62 Genes (12)DTX3, EGR3, NRIP1, CYP4F3, HEXIM1, RNF220, SRSF10, LCOR, TXNRD1, TPM2, SPIB Regulons (13)R-510, R-2382, R-1511, R-126, R-3008, R-2280, R-1151, R-2116, R-1563, R-2512, R-961, R-976, R-2727 |
| ENSG00000054598 | up-regulates | R-1000 | -0.380145 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| NF1 | up-regulates | R-130 | 0.381224 | Pr-109 Genes (12)MAN1B1, APOLD1, GEMIN4, GPR135, HIST2H2AB, MBP, ZXDB, FAM19A5, PPT2, DBNDD2, PGAM5, ETV6 Regulons (15)R-2714, R-1768, R-130, R-1972, R-2652, R-10, R-1079, R-1946, R-2505, R-2405, R-1478, R-1654, R-830, R-1773, R-170 |
| TP53 | down-regulates | R-369 | -0.383401 | Pr-117 Genes (51)LRRC25, MRPL48, CNTD1, EFCAB5, ZDHHC13, PPFIA3, TBL1XR1, IL17RA, POLR2L, KLHL28, SHARPIN, PHLDA2, IST1, SKA2, JRKL, TRMT12, WDR27, ADSSL1, SHC4, YTHDF3, ZNF267, OR2AG2, PTAR1, SLX4, PRPF40A, RABL6, ANXA4, WDR5B, MAFG, TOPORS, KCNMB2, MFAP3L, PHACTR4, TRIQK, SUPT4H1, LTC4S, DDX47, FIS1, CKLF, FAM185A, RARB, IRF4, HOXA3 Regulons (53)R-2087, R-1556, R-2707, R-342, R-2610, R-2252, R-62, R-1904, R-1388, R-1266, R-2882, R-369, R-451, R-1677, R-1495, R-1591, R-771, R-2371, R-2535, R-1846, R-945, R-500, R-986, R-2995, R-2886, R-630, R-2738, R-2991, R-1735, R-1032, R-643, R-2069, R-1485, R-2179, R-2961, R-157, R-2336, R-2142, R-2358, R-1271, R-1489, R-1734, R-2090, R-1742, R-2070, R-3168, R-2704, R-994, R-2335, R-1786, R-539, R-2068, R-1929 |
| IRF1 | up-regulates | R-184 | -0.386169 | Pr-14 Genes (17)TMEM70, TUBB6, PNMA1, CASKIN2, ANXA2R, MLF1, ARID3B, SLC17A8, FZD2, PLAG1, SLC8A1, SEMA4B, NOXA1, AKR1C3, MPV17L2 Regulons (18)R-1002, R-1429, R-1659, R-894, R-77, R-1832, R-1545, R-184, R-2284, R-2223, R-2075, R-2878, R-2606, R-1398, R-2952, R-1932, R-3170, R-2014 |
| HBP1 | up-regulates | R-1831 | -0.397545 | Pr-2 Genes (47)MSRA, PLEKHF2, NUPR1, IP6K1, TCP11L1, SPHK1, TYMS, FAM89B, WDR73, IRX3, ACAD9, CD151, KCNJ10, ARL6IP6, ODF3B, MPI, HYI, SPTY2D1, DAND5, ELMOD2, CDC42EP4, MAF1, SERTAD2, GLIPR1L2, LSMEM1, HIST3H2A, C5orf24, GINS3, RAD51B, MXRA7, BRICD5, RUVBL2, RBM12B, BRWD1, ANKRD37, TTC30B, SFI1, CTR9, CCDC167, PDXP Regulons (47)R-1855, R-2267, R-3037, R-486, R-2717, R-878, R-363, R-2104, R-631, R-3178, R-563, R-1911, R-436, R-183, R-2977, R-78, R-2479, R-2411, R-1825, R-49, R-272, R-390, R-1869, R-1831, R-2225, R-1586, R-775, R-535, R-1660, R-796, R-1574, R-1561, R-3126, R-2309, R-1717, R-2283, R-1341, R-2662, R-3007, R-2873, R-599, R-1189, R-2486, R-24, R-3064, R-570, R-288 |
| CEBPB | up-regulates | R-1770 | 0.400611 | Pr-99 Genes (28)GNG7, ZBTB34, APOBEC3B, PSMG4, HSF1, PRPF39, ARL15, CERKL, MSL1, ZNF79, PLXNB2, YTHDF2, TLK1, TSEN15, CAPZA2, FCGR3A, LIME1, SMIM5, C6orf47, DENND6B, LIN52, RBMXL1, EMP2, TMEM167B, ZSCAN31, CDRT4 Regulons (31)R-3174, R-453, R-1770, R-3083, R-1212, R-648, R-2506, R-2709, R-1696, R-2314, R-2642, R-587, R-492, R-1891, R-3063, R-640, R-2162, R-3070, R-1834, R-188, R-2140, R-2317, R-1435, R-3129, R-699, R-3090, R-650, R-1007, R-2844, R-2311, R-606 |
| SOX4 | down-regulates | R-2182 | -0.40215 | Pr-23 Genes (14)LRRTM4, LMNB2, B3GNT8, HLA-DQB1, TIGD5, FIZ1, C3orf58, CREB3L2, ALG12, BTN3A2, ENTPD5, TBC1D9B Regulons (14)R-2081, R-1884, R-1719, R-1839, R-2182, R-1274, R-2732, R-2344, R-477, R-3190, R-2889, R-309, R-371, R-444 |
| ZBTB3 | down-regulates | R-1274 | 0.404038 | Pr-23 Genes (14)LRRTM4, LMNB2, B3GNT8, HLA-DQB1, TIGD5, FIZ1, C3orf58, CREB3L2, ALG12, BTN3A2, ENTPD5, TBC1D9B Regulons (14)R-2081, R-1884, R-1719, R-1839, R-2182, R-1274, R-2732, R-2344, R-477, R-3190, R-2889, R-309, R-371, R-444 |
| RARA | up-regulates | R-172 | 0.405462 | Pr-134 Genes (104)MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1 Regulons (119)R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272 |
| HMGA1 | down-regulates | R-832 | 0.407077 | Pr-119 |
| FOXP1 | up-regulates | R-3121 | -0.417258 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| ZBTB3 | down-regulates | R-1275 | -0.421961 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| HOXA5 | down-regulates | R-22 | -0.436928 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| CEBPD | up-regulates | R-1312 | -0.440834 | Pr-126 Genes (12)MTURN, SAMD7, ISG15, TYW1, SFT2D2, PTPRCAP, APOBEC3G, MRPL33, CDK11B, PRR5-ARHGAP8, TERB1, UTP14C Regulons (15)R-1312, R-1710, R-128, R-366, R-2612, R-1442, R-981, R-2739, R-1647, R-1766, R-542, R-2672, R-2543, R-2638, R-3053 |
| PLAG1 | down-regulates | R-1516 | -0.4439 | Pr-58 Genes (28)ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28)R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148 |
| ETV2 | down-regulates | R-1511 | 0.447542 | Pr-62 Genes (12)DTX3, EGR3, NRIP1, CYP4F3, HEXIM1, RNF220, SRSF10, LCOR, TXNRD1, TPM2, SPIB Regulons (13)R-510, R-2382, R-1511, R-126, R-3008, R-2280, R-1151, R-2116, R-1563, R-2512, R-961, R-976, R-2727 |
| ENSG00000165066 | up-regulates | R-3083 | 0.448378 | Pr-99 Genes (28)GNG7, ZBTB34, APOBEC3B, PSMG4, HSF1, PRPF39, ARL15, CERKL, MSL1, ZNF79, PLXNB2, YTHDF2, TLK1, TSEN15, CAPZA2, FCGR3A, LIME1, SMIM5, C6orf47, DENND6B, LIN52, RBMXL1, EMP2, TMEM167B, ZSCAN31, CDRT4 Regulons (31)R-3174, R-453, R-1770, R-3083, R-1212, R-648, R-2506, R-2709, R-1696, R-2314, R-2642, R-587, R-492, R-1891, R-3063, R-640, R-2162, R-3070, R-1834, R-188, R-2140, R-2317, R-1435, R-3129, R-699, R-3090, R-650, R-1007, R-2844, R-2311, R-606 |
| ELF4 | up-regulates | R-2342 | -0.451214 | Pr-120 Genes (9)ANKLE2, TMEM52, YOD1, ZNF443, CDCA2, SIVA1, PSMD13, CHAMP1 Regulons (9)R-2299, R-2503, R-2342, R-546, R-2201, R-1346, R-1651, R-792, R-2963 |
| DR1 | up-regulates | R-44 | 0.451863 | Pr-132 |
| MAFG | up-regulates | R-1487 | 0.456604 | Pr-34 Genes (6)ACSF3, PPA1, CRIP2, TMEM216, MAGI2, TOGARAM1 Regulons (6)R-3038, R-1487, R-2881, R-1430, R-1835, R-2239 |
| BCL6 | up-regulates | R-546 | 0.459576 | Pr-120 Genes (9)ANKLE2, TMEM52, YOD1, ZNF443, CDCA2, SIVA1, PSMD13, CHAMP1 Regulons (9)R-2299, R-2503, R-2342, R-546, R-2201, R-1346, R-1651, R-792, R-2963 |
| BDP1 | down-regulates | R-841 | 0.461691 | Pr-118 Genes (18)ZNF169, CCDC121, LCORL, CUEDC1, ZBTB44, MIER1, ECI2, C4orf47, ZNF611, ERV3-1, HIGD1C, TOMM6, CSKMT, SMIM1, POU5F2, DPP3, EBLN2 Regulons (25)R-388, R-1185, R-2333, R-841, R-967, R-2625, R-125, R-1390, R-2192, R-1859, R-2750, R-1922, R-1788, R-842, R-1521, R-2694, R-131, R-1957, R-694, R-787, R-2413, R-2213, R-2689, R-1379, R-3146 |
| ENSG00000175832 | up-regulates | R-314 | 0.462821 | Pr-60 Genes (13)MYLPF, CXCR2, SCRIB, RNF41, PPP1R27, FAM167B, SIGIRR, NOC2L, KLHL14, SELENOH, STARD10, TNFSF12, SELENOP Regulons (16)R-12, R-2753, R-314, R-2433, R-1411, R-2357, R-2343, R-1509, R-1392, R-1657, R-2736, R-3179, R-1338, R-1887, R-354, R-1354 |
| FOXP1 | up-regulates | R-3120 | -0.467693 | Pr-6 Genes (31)SART1, C11orf68, TALDO1, GPR150, ZNF543, COX14, ZNF571, KCTD2, PRKAG1, CSF1R, VMO1, SMDT1, SF3A3, TTC32, XPOT, KRBA2, MED12, APOBR, SDR42E1, FMNL1, ZBTB37, L3MBTL1, TRABD2A, CD55, ZNF34, DCHS2, CRIP1, NDUFA7 Regulons (31)R-46, R-2648, R-3177, R-869, R-2895, R-64, R-940, R-1917, R-3120, R-435, R-697, R-2958, R-886, R-1865, R-2783, R-1396, R-1420, R-1057, R-2768, R-2047, R-2528, R-2603, R-557, R-178, R-2874, R-70, R-2298, R-2329, R-2561, R-651, R-1845 |
| ENSG00000054598 | up-regulates | R-999 | -0.478127 | Pr-0 Genes (84)GPX2, BNIP3, METRNL, PUS1, SAMD12, CD163, SLC25A20, EFCAB13, EXOSC4, SAMD4B, CATSPERE, C14orf119, ARHGAP45, BBS12, EHMT1, SETD2, ZBTB20, RFX7, TSKU, SRPRA, SLC25A10, ASB7, UPP1, LIN9, CCR10, ZFP1, USP18, TNFAIP2, CDNF, SOCS1, METTL7A, PDE6G, SP1, P4HB, DRG1, CXorf38, MORF4L1, AIDA, WWOX, SAPCD2, PPP1CC, SPIN4, CXCR3, ZNF397, TPCN1, CMC1, GCNT1, FNBP1, RSBN1L, LOC100288637, TMPPE, ZC3H6, ZNF669, NANOS1, ALKBH2, JPT1, LIN54, HLA-DRB1, ZNF493, EPHB4, TRAPPC2B, SIAH1, ESRRG, TCF4, SERTAD1, ZNF398, ZNF257, ATG7, MPEG1, RPS4X, PNP, HMGN2, HIST2H2BF, COLQ, RPS29 Regulons (86)R-180, R-2076, R-2157, R-3164, R-3147, R-338, R-2156, R-2409, R-885, R-941, R-1192, R-556, R-3197, R-1572, R-999, R-636, R-902, R-2541, R-440, R-890, R-3175, R-767, R-1542, R-1336, R-2472, R-1698, R-2326, R-1906, R-269, R-772, R-647, R-3033, R-2100, R-2711, R-1394, R-3068, R-508, R-63, R-1916, R-1188, R-532, R-2135, R-997, R-1687, R-2951, R-1853, R-2220, R-577, R-585, R-2597, R-1021, R-3119, R-301, R-559, R-1560, R-175, R-2870, R-3015, R-66, R-595, R-3185, R-2905, R-433, R-290, R-381, R-2509, R-562, R-2798, R-2206, R-1418, R-60, R-3050, R-2073, R-611, R-2488, R-881, R-1095, R-2153, R-2553, R-2305, R-2656, R-1697, R-511, R-2185, R-1492, R-2555 |
| BCL6 | up-regulates | R-535 | -0.478321 | Pr-2 Genes (47)MSRA, PLEKHF2, NUPR1, IP6K1, TCP11L1, SPHK1, TYMS, FAM89B, WDR73, IRX3, ACAD9, CD151, KCNJ10, ARL6IP6, ODF3B, MPI, HYI, SPTY2D1, DAND5, ELMOD2, CDC42EP4, MAF1, SERTAD2, GLIPR1L2, LSMEM1, HIST3H2A, C5orf24, GINS3, RAD51B, MXRA7, BRICD5, RUVBL2, RBM12B, BRWD1, ANKRD37, TTC30B, SFI1, CTR9, CCDC167, PDXP Regulons (47)R-1855, R-2267, R-3037, R-486, R-2717, R-878, R-363, R-2104, R-631, R-3178, R-563, R-1911, R-436, R-183, R-2977, R-78, R-2479, R-2411, R-1825, R-49, R-272, R-390, R-1869, R-1831, R-2225, R-1586, R-775, R-535, R-1660, R-796, R-1574, R-1561, R-3126, R-2309, R-1717, R-2283, R-1341, R-2662, R-3007, R-2873, R-599, R-1189, R-2486, R-24, R-3064, R-570, R-288 |
| ELK1 | up-regulates | R-636 | 0.485452 | Pr-0 Genes (84)GPX2, BNIP3, METRNL, PUS1, SAMD12, CD163, SLC25A20, EFCAB13, EXOSC4, SAMD4B, CATSPERE, C14orf119, ARHGAP45, BBS12, EHMT1, SETD2, ZBTB20, RFX7, TSKU, SRPRA, SLC25A10, ASB7, UPP1, LIN9, CCR10, ZFP1, USP18, TNFAIP2, CDNF, SOCS1, METTL7A, PDE6G, SP1, P4HB, DRG1, CXorf38, MORF4L1, AIDA, WWOX, SAPCD2, PPP1CC, SPIN4, CXCR3, ZNF397, TPCN1, CMC1, GCNT1, FNBP1, RSBN1L, LOC100288637, TMPPE, ZC3H6, ZNF669, NANOS1, ALKBH2, JPT1, LIN54, HLA-DRB1, ZNF493, EPHB4, TRAPPC2B, SIAH1, ESRRG, TCF4, SERTAD1, ZNF398, ZNF257, ATG7, MPEG1, RPS4X, PNP, HMGN2, HIST2H2BF, COLQ, RPS29 Regulons (86)R-180, R-2076, R-2157, R-3164, R-3147, R-338, R-2156, R-2409, R-885, R-941, R-1192, R-556, R-3197, R-1572, R-999, R-636, R-902, R-2541, R-440, R-890, R-3175, R-767, R-1542, R-1336, R-2472, R-1698, R-2326, R-1906, R-269, R-772, R-647, R-3033, R-2100, R-2711, R-1394, R-3068, R-508, R-63, R-1916, R-1188, R-532, R-2135, R-997, R-1687, R-2951, R-1853, R-2220, R-577, R-585, R-2597, R-1021, R-3119, R-301, R-559, R-1560, R-175, R-2870, R-3015, R-66, R-595, R-3185, R-2905, R-433, R-290, R-381, R-2509, R-562, R-2798, R-2206, R-1418, R-60, R-3050, R-2073, R-611, R-2488, R-881, R-1095, R-2153, R-2553, R-2305, R-2656, R-1697, R-511, R-2185, R-1492, R-2555 |
| ELF1 | up-regulates | R-2994 | 0.486807 | Pr-8 Genes (12)F2R, NPLOC4, COA5, TMEM17, MESP2, SLC29A3, CPNE1, RBM14, ADSL, CNTF, MRPL46, SRXN1 Regulons (25)R-2994, R-1711, R-449, R-2248, R-1649, R-1658, R-3028, R-2489, R-1433, R-94, R-632, R-2548, R-3020, R-3006, R-2051, R-233, R-3160, R-665, R-181, R-75, R-2633, R-2210, R-2434, R-1060, R-230 |
| RFX3 | up-regulates | R-1660 | -0.495816 | Pr-2 Genes (47)MSRA, PLEKHF2, NUPR1, IP6K1, TCP11L1, SPHK1, TYMS, FAM89B, WDR73, IRX3, ACAD9, CD151, KCNJ10, ARL6IP6, ODF3B, MPI, HYI, SPTY2D1, DAND5, ELMOD2, CDC42EP4, MAF1, SERTAD2, GLIPR1L2, LSMEM1, HIST3H2A, C5orf24, GINS3, RAD51B, MXRA7, BRICD5, RUVBL2, RBM12B, BRWD1, ANKRD37, TTC30B, SFI1, CTR9, CCDC167, PDXP Regulons (47)R-1855, R-2267, R-3037, R-486, R-2717, R-878, R-363, R-2104, R-631, R-3178, R-563, R-1911, R-436, R-183, R-2977, R-78, R-2479, R-2411, R-1825, R-49, R-272, R-390, R-1869, R-1831, R-2225, R-1586, R-775, R-535, R-1660, R-796, R-1574, R-1561, R-3126, R-2309, R-1717, R-2283, R-1341, R-2662, R-3007, R-2873, R-599, R-1189, R-2486, R-24, R-3064, R-570, R-288 |
| FOXO1 | up-regulates | R-1406 | 0.499782 | Pr-18 Genes (11)RPRM, FRAT2, SCFD2, PARPBP, ADAT2, INCA1, CASP4, DDRGK1, DDR1 Regulons (15)R-127, R-1406, R-1883, R-89, R-221, R-1440, R-604, R-2385, R-2515, R-1076, R-165, R-2899, R-2246, R-2731, R-1671 |
| REL | up-regulates | R-1278 | 0.502416 | Pr-9 Genes (30)SLC26A11, DDX60L, CA13, RAB11B, SOWAHB, GNG2, UBE2H, KIF24, PLSCR1, ANKDD1B, EVL, TECPR2, NF1, SIGLEC15, PCBP2, LOC105369247, ZNF624, S100A10, PLN, CALM1, TTC37, ANKRD13B, ZNF652, RCSD1, ARHGAP11A, DCAF12, SMC5, C10orf128 Regulons (30)R-1534, R-1278, R-2296, R-1107, R-159, R-52, R-1264, R-4, R-1953, R-1718, R-273, R-2166, R-2728, R-195, R-1344, R-503, R-2613, R-1878, R-541, R-2806, R-1583, R-2340, R-2143, R-2480, R-1408, R-2570, R-2061, R-2654, R-1476, R-442 |
| TGIF1 | up-regulates | R-2508 | 0.506963 | Pr-134 Genes (104)MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1 Regulons (119)R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272 |
| JUN | up-regulates | R-1177 | 0.50809 | Pr-138 Genes (9)SYNE3, SEC24C, WSCD1, RAP2B, ODF3L1, SEMA4A, SLC9A6, PATL2, C2orf15 Regulons (12)R-1666, R-2981, R-2567, R-1177, R-133, R-3011, R-472, R-11, R-169, R-2271, R-1668, R-1842 |
| RORA | down-regulates | R-2274 | 0.508233 | Pr-129 Genes (12)DALRD3, CTNNBIP1, FAHD1, ZBTB2, SLC2A4, UBA7, KLHDC8B, BCDIN3D, FAM111B, MAN1A2, HYLS1, INF2 Regulons (12)R-356, R-1920, R-2758, R-2274, R-507, R-1886, R-1777, R-1479, R-1180, R-2321, R-756, R-1179 |
| ARID3A | down-regulates | R-1342 | 0.515151 | Pr-58 Genes (28)ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28)R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148 |
| SPDEF | down-regulates | R-1972 | -0.517954 | Pr-109 Genes (12)MAN1B1, APOLD1, GEMIN4, GPR135, HIST2H2AB, MBP, ZXDB, FAM19A5, PPT2, DBNDD2, PGAM5, ETV6 Regulons (15)R-2714, R-1768, R-130, R-1972, R-2652, R-10, R-1079, R-1946, R-2505, R-2405, R-1478, R-1654, R-830, R-1773, R-170 |
| RFX3 | up-regulates | R-1677 | 0.519248 | Pr-117 Genes (51)LRRC25, MRPL48, CNTD1, EFCAB5, ZDHHC13, PPFIA3, TBL1XR1, IL17RA, POLR2L, KLHL28, SHARPIN, PHLDA2, IST1, SKA2, JRKL, TRMT12, WDR27, ADSSL1, SHC4, YTHDF3, ZNF267, OR2AG2, PTAR1, SLX4, PRPF40A, RABL6, ANXA4, WDR5B, MAFG, TOPORS, KCNMB2, MFAP3L, PHACTR4, TRIQK, SUPT4H1, LTC4S, DDX47, FIS1, CKLF, FAM185A, RARB, IRF4, HOXA3 Regulons (53)R-2087, R-1556, R-2707, R-342, R-2610, R-2252, R-62, R-1904, R-1388, R-1266, R-2882, R-369, R-451, R-1677, R-1495, R-1591, R-771, R-2371, R-2535, R-1846, R-945, R-500, R-986, R-2995, R-2886, R-630, R-2738, R-2991, R-1735, R-1032, R-643, R-2069, R-1485, R-2179, R-2961, R-157, R-2336, R-2142, R-2358, R-1271, R-1489, R-1734, R-2090, R-1742, R-2070, R-3168, R-2704, R-994, R-2335, R-1786, R-539, R-2068, R-1929 |
| ZFX | up-regulates | R-1926 | 0.529957 | Pr-51 |
| EP300 | up-regulates | R-2433 | 0.537146 | Pr-60 Genes (13)MYLPF, CXCR2, SCRIB, RNF41, PPP1R27, FAM167B, SIGIRR, NOC2L, KLHL14, SELENOH, STARD10, TNFSF12, SELENOP Regulons (16)R-12, R-2753, R-314, R-2433, R-1411, R-2357, R-2343, R-1509, R-1392, R-1657, R-2736, R-3179, R-1338, R-1887, R-354, R-1354 |
| FOXO1 | up-regulates | R-1417 | -0.539502 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| FOXJ3 | up-regulates | R-2880 | -0.549489 | Pr-105 Genes (8)ERCC4, IDH2, ZNF490, FAM83G, ASPH, EXOC3L4, SLC48A1 Regulons (8)R-1072, R-2880, R-821, R-1432, R-81, R-2380, R-582, R-3000 |
| HMBOX1 | up-regulates | R-2379 | -0.550956 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| MAFG | up-regulates | R-1495 | 0.551417 | Pr-117 Genes (51)LRRC25, MRPL48, CNTD1, EFCAB5, ZDHHC13, PPFIA3, TBL1XR1, IL17RA, POLR2L, KLHL28, SHARPIN, PHLDA2, IST1, SKA2, JRKL, TRMT12, WDR27, ADSSL1, SHC4, YTHDF3, ZNF267, OR2AG2, PTAR1, SLX4, PRPF40A, RABL6, ANXA4, WDR5B, MAFG, TOPORS, KCNMB2, MFAP3L, PHACTR4, TRIQK, SUPT4H1, LTC4S, DDX47, FIS1, CKLF, FAM185A, RARB, IRF4, HOXA3 Regulons (53)R-2087, R-1556, R-2707, R-342, R-2610, R-2252, R-62, R-1904, R-1388, R-1266, R-2882, R-369, R-451, R-1677, R-1495, R-1591, R-771, R-2371, R-2535, R-1846, R-945, R-500, R-986, R-2995, R-2886, R-630, R-2738, R-2991, R-1735, R-1032, R-643, R-2069, R-1485, R-2179, R-2961, R-157, R-2336, R-2142, R-2358, R-1271, R-1489, R-1734, R-2090, R-1742, R-2070, R-3168, R-2704, R-994, R-2335, R-1786, R-539, R-2068, R-1929 |
| BACH1 | up-regulates | R-477 | 0.551978 | Pr-23 Genes (14)LRRTM4, LMNB2, B3GNT8, HLA-DQB1, TIGD5, FIZ1, C3orf58, CREB3L2, ALG12, BTN3A2, ENTPD5, TBC1D9B Regulons (14)R-2081, R-1884, R-1719, R-1839, R-2182, R-1274, R-2732, R-2344, R-477, R-3190, R-2889, R-309, R-371, R-444 |
| FOXP1 | up-regulates | R-3126 | -0.555658 | Pr-2 Genes (47)MSRA, PLEKHF2, NUPR1, IP6K1, TCP11L1, SPHK1, TYMS, FAM89B, WDR73, IRX3, ACAD9, CD151, KCNJ10, ARL6IP6, ODF3B, MPI, HYI, SPTY2D1, DAND5, ELMOD2, CDC42EP4, MAF1, SERTAD2, GLIPR1L2, LSMEM1, HIST3H2A, C5orf24, GINS3, RAD51B, MXRA7, BRICD5, RUVBL2, RBM12B, BRWD1, ANKRD37, TTC30B, SFI1, CTR9, CCDC167, PDXP Regulons (47)R-1855, R-2267, R-3037, R-486, R-2717, R-878, R-363, R-2104, R-631, R-3178, R-563, R-1911, R-436, R-183, R-2977, R-78, R-2479, R-2411, R-1825, R-49, R-272, R-390, R-1869, R-1831, R-2225, R-1586, R-775, R-535, R-1660, R-796, R-1574, R-1561, R-3126, R-2309, R-1717, R-2283, R-1341, R-2662, R-3007, R-2873, R-599, R-1189, R-2486, R-24, R-3064, R-570, R-288 |
| NR3C1 | down-regulates | R-3181 | -0.557618 | Pr-12 Genes (14)CDK5R1, C18orf32, ARL6IP4, NELFA, INTS5, TCEAL9, ZNF431, ZNF81, FAM49A, ARMH1, C2CD4A, GIGYF2, SPIRE2, TMA7 Regulons (17)R-776, R-1187, R-3181, R-555, R-2154, R-2189, R-1434, R-189, R-3127, R-2242, R-1403, R-281, R-2291, R-2193, R-1033, R-1861, R-2245 |
| XBP1 | down-regulates | R-3052 | 0.559099 | Pr-108 Genes (9)EXT1, DUSP8, TSPYL4, PSMD12, SGTB, PHB2, TMEM242, TMEM238, FOS Regulons (49)R-3052, R-2626, R-660, R-1517, R-1106, R-2339, R-3027, R-196, R-897, R-1502, R-3088, R-1284, R-1518, R-1519, R-382, R-609, R-868, R-2177, R-1424, R-875, R-2475, R-2259, R-1301, R-2105, R-2729, R-1055, R-2262, R-1214, R-2632, R-2209, R-1067, R-179, R-303, R-1689, R-2137, R-1744, R-1759, R-2761, R-1216, R-34, R-1640, R-1731, R-2363, R-502, R-2686, R-2178, R-1740, R-232, R-618 |
| ENSG00000245848 | up-regulates | R-1656 | 0.559247 | Pr-134 Genes (104)MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1 Regulons (119)R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272 |
| ELF4 | up-regulates | R-2345 | 0.565136 | Pr-7 Genes (38)UFSP1, SLC35G1, IMP3, R3HDM2, RNF135, HKR1, ATP6AP2, SATB1, RBM10, CRELD2, SNRNP35, ZDHHC23, AMER1, PTRHD1, NDUFA6, MAFF, PRMT3, RGPD2, ATP6V0C, C16orf54, IRS2, MKL2, FAM86B2, PRR5, ZNF33A, XRCC6, TSC22D2, SLC6A9, ADAM32, NOL4L, SERPINA1, EME2, ENTPD7, PJA2 Regulons (39)R-1139, R-308, R-1195, R-2247, R-2754, R-1584, R-1923, R-1849, R-2345, R-370, R-226, R-1013, R-2065, R-2181, R-2145, R-2843, R-1003, R-1410, R-2796, R-3012, R-1347, R-3136, R-1650, R-543, R-53, R-2571, R-1879, R-1738, R-2557, R-1968, R-1562, R-3067, R-788, R-1840, R-2230, R-471, R-1667, R-3165, R-361 |
| ZBTB3 | down-regulates | R-1272 | -0.568661 | Pr-85 Genes (18)A2M, ANAPC2, NIM1K, ZFAND2A, GCC1, ERCC6L2, UBE2E2, MTA1, TOB2, SNAI3, RINL, SMIM15, SULT1C2, SMG5, SYS1, CDPF1, SLC12A8, ITGB3 Regulons (21)R-2966, R-484, R-3159, R-597, R-661, R-1688, R-1272, R-2328, R-615, R-2366, R-2374, R-2647, R-360, R-977, R-3017, R-1311, R-622, R-3187, R-2071, R-3002, R-2492 |
| IKZF1 | up-regulates | R-991 | 0.573701 | Pr-124 Genes (20)MYPOP, DMAP1, PER1, C1S, DENND5A, TSPYL2, KNTC1, TMEM105, LRCH3, ZBTB6, CFAP73, LILRB4, TNFRSF18, LITAF, ZNF665, IPO7, KMT2B Regulons (20)R-1400, R-1425, R-1962, R-1828, R-991, R-1083, R-1577, R-72, R-2158, R-3069, R-2814, R-1149, R-1631, R-182, R-1340, R-3034, R-3139, R-39, R-199, R-593 |
| GABPB1 | up-regulates | R-1948 | 0.575567 | Pr-35 Genes (10)ZBTB7A, TMEM107, BHLHA15, GLTPD2, ZNF395, MAFB, SMIM13, AKAP2, FOX3A Regulons (20)R-2747, R-3059, R-336, R-2624, R-1948, R-14, R-277, R-2826, R-1570, R-1094, R-1244, R-2621, R-1232, R-1506, R-3019, R-493, R-1945, R-2691, R-1963, R-2244 |
| ENSG00000245848 | up-regulates | R-1642 | 0.576599 | Pr-134 Genes (104)MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1 Regulons (119)R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272 |
| ENSG00000162367 | up-regulates | R-1711 | 0.576626 | Pr-8 Genes (12)F2R, NPLOC4, COA5, TMEM17, MESP2, SLC29A3, CPNE1, RBM14, ADSL, CNTF, MRPL46, SRXN1 Regulons (25)R-2994, R-1711, R-449, R-2248, R-1649, R-1658, R-3028, R-2489, R-1433, R-94, R-632, R-2548, R-3020, R-3006, R-2051, R-233, R-3160, R-665, R-181, R-75, R-2633, R-2210, R-2434, R-1060, R-230 |
| ENSG00000135638 | down-regulates | R-1958 | 0.576875 | Pr-121 |
| IRF4 | down-regulates | R-490 | -0.580544 | Pr-40 Genes (9)DDX10, GLRX5, BTLA, MCRS1, PDCD1, H2AFX, FBF1, H1F0, GREB1 Regulons (9)R-2801, R-490, R-1084, R-1092, R-1152, R-494, R-1090, R-192, R-1154 |
| ELF1 | up-regulates | R-2984 | -0.581395 | Pr-25 Genes (9)RNPEP, RUFY1, ZNF664, TRNAU1AP, CLEC4G, SRC, HLA-F, RTL5 Regulons (9)R-974, R-1686, R-160, R-709, R-2312, R-2984, R-2341, R-2802, R-3062 |
| TP53 | down-regulates | R-370 | 0.58214 | Pr-7 Genes (38)UFSP1, SLC35G1, IMP3, R3HDM2, RNF135, HKR1, ATP6AP2, SATB1, RBM10, CRELD2, SNRNP35, ZDHHC23, AMER1, PTRHD1, NDUFA6, MAFF, PRMT3, RGPD2, ATP6V0C, C16orf54, IRS2, MKL2, FAM86B2, PRR5, ZNF33A, XRCC6, TSC22D2, SLC6A9, ADAM32, NOL4L, SERPINA1, EME2, ENTPD7, PJA2 Regulons (39)R-1139, R-308, R-1195, R-2247, R-2754, R-1584, R-1923, R-1849, R-2345, R-370, R-226, R-1013, R-2065, R-2181, R-2145, R-2843, R-1003, R-1410, R-2796, R-3012, R-1347, R-3136, R-1650, R-543, R-53, R-2571, R-1879, R-1738, R-2557, R-1968, R-1562, R-3067, R-788, R-1840, R-2230, R-471, R-1667, R-3165, R-361 |
| ATF1 | up-regulates | R-565 | 0.583166 | Pr-130 Genes (6)ULK1, AURKB, ACTL10, ZFP36L1, PEAK3, IRF9 Regulons (8)R-373, R-2661, R-565, R-300, R-1080, R-2631, R-1714, R-1407 |
| POU2F1 | up-regulates | R-80 | 0.583193 | Pr-29 Genes (9)P2RY2, SAMD9L, TMEM187, TRAK1, ANKRD45, PTP4A2, ZNF565, C17orf51 Regulons (9)R-1401, R-1870, R-1733, R-80, R-2197, R-993, R-1308, R-2683, R-548 |
| FOXO1 | up-regulates | R-1411 | 0.58467 | Pr-60 Genes (13)MYLPF, CXCR2, SCRIB, RNF41, PPP1R27, FAM167B, SIGIRR, NOC2L, KLHL14, SELENOH, STARD10, TNFSF12, SELENOP Regulons (16)R-12, R-2753, R-314, R-2433, R-1411, R-2357, R-2343, R-1509, R-1392, R-1657, R-2736, R-3179, R-1338, R-1887, R-354, R-1354 |
| TGIF1 | up-regulates | R-2501 | 0.587545 | Pr-122 Genes (6)NSUN3, EIF3K, ANXA2, LCK, TLR7, PAM16 Regulons (21)R-2218, R-3042, R-2501, R-2962, R-1078, R-1900, R-1098, R-2812, R-2168, R-1712, R-27, R-2760, R-1892, R-680, R-2370, R-1248, R-1693, R-2525, R-2673, R-1772, R-519 |
| POU2F1 | up-regulates | R-71 | -0.58757 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| FOXJ3 | up-regulates | R-2881 | -0.590232 | Pr-34 Genes (6)ACSF3, PPA1, CRIP2, TMEM216, MAGI2, TOGARAM1 Regulons (6)R-3038, R-1487, R-2881, R-1430, R-1835, R-2239 |
| TFEB | up-regulates | R-886 | -0.591963 | Pr-6 Genes (31)SART1, C11orf68, TALDO1, GPR150, ZNF543, COX14, ZNF571, KCTD2, PRKAG1, CSF1R, VMO1, SMDT1, SF3A3, TTC32, XPOT, KRBA2, MED12, APOBR, SDR42E1, FMNL1, ZBTB37, L3MBTL1, TRABD2A, CD55, ZNF34, DCHS2, CRIP1, NDUFA7 Regulons (31)R-46, R-2648, R-3177, R-869, R-2895, R-64, R-940, R-1917, R-3120, R-435, R-697, R-2958, R-886, R-1865, R-2783, R-1396, R-1420, R-1057, R-2768, R-2047, R-2528, R-2603, R-557, R-178, R-2874, R-70, R-2298, R-2329, R-2561, R-651, R-1845 |
| HOXA3 | down-regulates | R-226 | -0.597612 | Pr-7 Genes (38)UFSP1, SLC35G1, IMP3, R3HDM2, RNF135, HKR1, ATP6AP2, SATB1, RBM10, CRELD2, SNRNP35, ZDHHC23, AMER1, PTRHD1, NDUFA6, MAFF, PRMT3, RGPD2, ATP6V0C, C16orf54, IRS2, MKL2, FAM86B2, PRR5, ZNF33A, XRCC6, TSC22D2, SLC6A9, ADAM32, NOL4L, SERPINA1, EME2, ENTPD7, PJA2 Regulons (39)R-1139, R-308, R-1195, R-2247, R-2754, R-1584, R-1923, R-1849, R-2345, R-370, R-226, R-1013, R-2065, R-2181, R-2145, R-2843, R-1003, R-1410, R-2796, R-3012, R-1347, R-3136, R-1650, R-543, R-53, R-2571, R-1879, R-1738, R-2557, R-1968, R-1562, R-3067, R-788, R-1840, R-2230, R-471, R-1667, R-3165, R-361 |
| ZBTB3 | down-regulates | R-1270 | 0.603274 | Pr-134 Genes (104)MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1 Regulons (119)R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272 |
| MAFG | up-regulates | R-1497 | 0.606698 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| STAT1 | down-regulates | R-3073 | -0.609623 | Pr-136 Genes (30)TPRN, WRB, IFITM2, LILRA5, C2orf88, RILPL1, TUBB4B, KAZN, FAM72D, GAL3ST4, SREBF2, CENPW, SARNP, MFSD2B, FGFR1OP, GPC2, SRA1, LBH, FAM200A, OST4, KIFC1, APOPT1, S1PR2, FOXJ1, TGIF1 Regulons (34)R-1265, R-2164, R-193, R-3073, R-638, R-2640, R-2531, R-2238, R-331, R-0, R-339, R-2845, R-1902, R-2701, R-1452, R-702, R-695, R-2566, R-1421, R-2803, R-1827, R-2404, R-2705, R-1453, R-2266, R-87, R-834, R-779, R-1471, R-335, R-1571, R-970, R-2751, R-1629 |
| PLAG1 | down-regulates | R-1520 | -0.621542 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| ENSG00000105610 | up-regulates | R-207 | 0.622884 | Pr-134 Genes (104)MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1 Regulons (119)R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272 |
| ENSG00000168269 | down-regulates | R-1569 | -0.622926 | Pr-54 |
| RUNX3 | up-regulates | R-901 | -0.632441 | Pr-135 Genes (24)LYSMD3, MTHFR, NEB, MX2, PCBP3, CHRM5, WDR53, TOR3A, CCDC30, ZDHHC17, SLC38A3, ZNF429, PIWIL2, SLC22A5, MCMBP, PRIM1, SZT2, HNRNPUL2, CEBPD, ATXN1L, N4BP2L2, MARS2 Regulons (38)R-311, R-2304, R-610, R-973, R-901, R-2103, R-341, R-717, R-2293, R-2067, R-337, R-1454, R-979, R-1555, R-2536, R-2985, R-1455, R-2617, R-1956, R-2167, R-791, R-785, R-672, R-2847, R-2083, R-1091, R-1890, R-1299, R-1874, R-2406, R-1269, R-1942, R-389, R-2263, R-1692, R-2199, R-1523, R-1230 |
| TP53 | down-regulates | R-377 | -0.637451 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| ARID3A | down-regulates | R-1341 | -0.641665 | Pr-2 Genes (47)MSRA, PLEKHF2, NUPR1, IP6K1, TCP11L1, SPHK1, TYMS, FAM89B, WDR73, IRX3, ACAD9, CD151, KCNJ10, ARL6IP6, ODF3B, MPI, HYI, SPTY2D1, DAND5, ELMOD2, CDC42EP4, MAF1, SERTAD2, GLIPR1L2, LSMEM1, HIST3H2A, C5orf24, GINS3, RAD51B, MXRA7, BRICD5, RUVBL2, RBM12B, BRWD1, ANKRD37, TTC30B, SFI1, CTR9, CCDC167, PDXP Regulons (47)R-1855, R-2267, R-3037, R-486, R-2717, R-878, R-363, R-2104, R-631, R-3178, R-563, R-1911, R-436, R-183, R-2977, R-78, R-2479, R-2411, R-1825, R-49, R-272, R-390, R-1869, R-1831, R-2225, R-1586, R-775, R-535, R-1660, R-796, R-1574, R-1561, R-3126, R-2309, R-1717, R-2283, R-1341, R-2662, R-3007, R-2873, R-599, R-1189, R-2486, R-24, R-3064, R-570, R-288 |
| SMAD4 | up-regulates | R-2357 | -0.642425 | Pr-60 Genes (13)MYLPF, CXCR2, SCRIB, RNF41, PPP1R27, FAM167B, SIGIRR, NOC2L, KLHL14, SELENOH, STARD10, TNFSF12, SELENOP Regulons (16)R-12, R-2753, R-314, R-2433, R-1411, R-2357, R-2343, R-1509, R-1392, R-1657, R-2736, R-3179, R-1338, R-1887, R-354, R-1354 |
| HSF2 | up-regulates | R-3167 | 0.645152 | Pr-3 Genes (46)ALG10B, ZNF613, VPS37D, CLVS1, GATD1, ERN1, RPP25, TSHZ1, ZADH2, TIGD2, MIGA1, P2RY13, ZNF101, COA4, CHST15, NOP10, GJC1, DAZAP2, UTP11, DGCR6, SATL1, RBM43, IFNLR1, IRF7, BLOC1S5, PARVB, PIK3R4, ABCB8, DDI2, DACT3, CXorf40A, ZNF277, MICB, NUP62, TSPAN4, MKRN2OS, FAM133B, ST20-MTHFS Regulons (49)R-2619, R-2148, R-3054, R-2410, R-228, R-3004, R-2876, R-1907, R-1191, R-2490, R-2769, R-1000, R-3121, R-1275, R-22, R-2325, R-1866, R-2285, R-1417, R-1960, R-2379, R-71, R-1497, R-1520, R-377, R-3167, R-1699, R-663, R-1069, R-2228, R-2232, R-2112, R-3141, R-836, R-333, R-827, R-194, R-2955, R-2322, R-1155, R-1588, R-586, R-1939, R-1215, R-2532, R-167, R-3010, R-1589, R-829 |
| FOXJ3 | up-regulates | R-2878 | -0.651802 | Pr-14 Genes (17)TMEM70, TUBB6, PNMA1, CASKIN2, ANXA2R, MLF1, ARID3B, SLC17A8, FZD2, PLAG1, SLC8A1, SEMA4B, NOXA1, AKR1C3, MPV17L2 Regulons (18)R-1002, R-1429, R-1659, R-894, R-77, R-1832, R-1545, R-184, R-2284, R-2223, R-2075, R-2878, R-2606, R-1398, R-2952, R-1932, R-3170, R-2014 |
| EWSR1 | up-regulates | R-2559 | 0.652492 | Pr-125 Genes (16)RPS6KA3, GBA, HMGN4, CMTM4, TEAD1, BCAM, NIF3L1, MKL1, CR1, RING1, PVRIG, GET4, LOC102724159, PI4KA, SMIM20 Regulons (17)R-589, R-1538, R-54, R-2559, R-2953, R-223, R-1504, R-1914, R-3162, R-2359, R-1975, R-2741, R-2547, R-892, R-482, R-2476, R-1703 |
| ELF3 | up-regulates | R-2141 | -0.655011 | Pr-39 Genes (11)PAAF1, KDF1, CD28, MAF, TBK1, PGP, FCAR, APOL6, SIGLEC14, MTRNR2L2 Regulons (17)R-889, R-2846, R-1954, R-558, R-2141, R-1857, R-708, R-378, R-1343, R-2900, R-1704, R-2347, R-2988, R-2552, R-1245, R-474, R-2797 |
| NFYC | up-regulates | R-298 | -0.660463 | Pr-59 Genes (15)DRAP1, MRPS23, CBX6, NDUFA12, UBALD2, MUC1, PBX1, PRELP, CFD, MPZL1, TBC1D8, STK38L, PCDHGA5, POC1B-GALNT4 Regulons (18)R-3140, R-2080, R-298, R-786, R-619, R-1472, R-450, R-601, R-2301, R-1564, R-654, R-2795, R-2891, R-3058, R-2183, R-1508, R-2708, R-658 |
| CEBPB | up-regulates | R-1767 | -0.661208 | Pr-4 Genes (37)B3GNT4, ZNF575, CRACR2B, ALS2CL, TCAIM, MED14, ADO, SFXN4, TM2D3, GAS2L1, EIF4EBP1, COL4A5, LRRK2, MXD3, ZBED8, CFAP97D1, WDR92, TMEM141, USP51, ZNF260, MTRNR2L8, CLLU1, CHURC1, CEP95, MRPL12, RPS10-NUDT3, YY1, BACH2, E2F2 Regulons (47)R-295, R-2879, R-2639, R-2318, R-3043, R-1908, R-1695, R-1554, R-2485, R-1767, R-777, R-443, R-1753, R-2114, R-1585, R-2824, R-1670, R-560, R-293, R-773, R-2432, R-270, R-2099, R-778, R-1778, R-1633, R-1277, R-1463, R-818, R-176, R-1573, R-1468, R-2599, R-2799, R-68, R-2950, R-2767, R-1174, R-990, R-2658, R-2221, R-2487, R-1684, R-3051, R-2813, R-1017, R-506 |
| TP53 | down-regulates | R-367 | -0.661782 | Pr-102 Genes (10)CCR4, KPNA4, NANOS3, NHLRC1, HIST3H2BB, DDX42, SH3D21, ZNF345, PINX1, CCPG1 Regulons (13)R-367, R-985, R-553, R-2155, R-2062, R-1380, R-2947, R-1355, R-1937, R-3060, R-769, R-522, R-2706 |
| ZNF281 | up-regulates | R-2472 | -0.661858 | Pr-0 Genes (84)GPX2, BNIP3, METRNL, PUS1, SAMD12, CD163, SLC25A20, EFCAB13, EXOSC4, SAMD4B, CATSPERE, C14orf119, ARHGAP45, BBS12, EHMT1, SETD2, ZBTB20, RFX7, TSKU, SRPRA, SLC25A10, ASB7, UPP1, LIN9, CCR10, ZFP1, USP18, TNFAIP2, CDNF, SOCS1, METTL7A, PDE6G, SP1, P4HB, DRG1, CXorf38, MORF4L1, AIDA, WWOX, SAPCD2, PPP1CC, SPIN4, CXCR3, ZNF397, TPCN1, CMC1, GCNT1, FNBP1, RSBN1L, LOC100288637, TMPPE, ZC3H6, ZNF669, NANOS1, ALKBH2, JPT1, LIN54, HLA-DRB1, ZNF493, EPHB4, TRAPPC2B, SIAH1, ESRRG, TCF4, SERTAD1, ZNF398, ZNF257, ATG7, MPEG1, RPS4X, PNP, HMGN2, HIST2H2BF, COLQ, RPS29 Regulons (86)R-180, R-2076, R-2157, R-3164, R-3147, R-338, R-2156, R-2409, R-885, R-941, R-1192, R-556, R-3197, R-1572, R-999, R-636, R-902, R-2541, R-440, R-890, R-3175, R-767, R-1542, R-1336, R-2472, R-1698, R-2326, R-1906, R-269, R-772, R-647, R-3033, R-2100, R-2711, R-1394, R-3068, R-508, R-63, R-1916, R-1188, R-532, R-2135, R-997, R-1687, R-2951, R-1853, R-2220, R-577, R-585, R-2597, R-1021, R-3119, R-301, R-559, R-1560, R-175, R-2870, R-3015, R-66, R-595, R-3185, R-2905, R-433, R-290, R-381, R-2509, R-562, R-2798, R-2206, R-1418, R-60, R-3050, R-2073, R-611, R-2488, R-881, R-1095, R-2153, R-2553, R-2305, R-2656, R-1697, R-511, R-2185, R-1492, R-2555 |
| NFATC1 | up-regulates | R-2197 | 0.666306 | Pr-29 Genes (9)P2RY2, SAMD9L, TMEM187, TRAK1, ANKRD45, PTP4A2, ZNF565, C17orf51 Regulons (9)R-1401, R-1870, R-1733, R-80, R-2197, R-993, R-1308, R-2683, R-548 |
| IKZF1 | up-regulates | R-993 | 0.673265 | Pr-29 Genes (9)P2RY2, SAMD9L, TMEM187, TRAK1, ANKRD45, PTP4A2, ZNF565, C17orf51 Regulons (9)R-1401, R-1870, R-1733, R-80, R-2197, R-993, R-1308, R-2683, R-548 |
| JUN | up-regulates | R-1175 | 0.678783 | Pr-137 Genes (22)KCNE3, SUGCT, SLC35A4, COX8A, PRR15, PFN4, FAM91A1, TMEM94, C14orf28, CMTR2, NQO1, FAM120C, PTPN1, SLC25A29, TMA16, MZT1, CSNK1E, KCTD7, CDK3, CHMP1B, COMMD3-BMI1 Regulons (23)R-2269, R-1302, R-186, R-1876, R-790, R-972, R-782, R-1579, R-1150, R-704, R-1950, R-1175, R-1457, R-1988, R-1345, R-713, R-3084, R-291, R-784, R-1348, R-2965, R-1533, R-1377 |
| MEF2D | down-regulates | R-877 | 0.682478 | Pr-55 |
| ENSG00000054598 | up-regulates | R-1013 | 0.682955 | Pr-7 Genes (38)UFSP1, SLC35G1, IMP3, R3HDM2, RNF135, HKR1, ATP6AP2, SATB1, RBM10, CRELD2, SNRNP35, ZDHHC23, AMER1, PTRHD1, NDUFA6, MAFF, PRMT3, RGPD2, ATP6V0C, C16orf54, IRS2, MKL2, FAM86B2, PRR5, ZNF33A, XRCC6, TSC22D2, SLC6A9, ADAM32, NOL4L, SERPINA1, EME2, ENTPD7, PJA2 Regulons (39)R-1139, R-308, R-1195, R-2247, R-2754, R-1584, R-1923, R-1849, R-2345, R-370, R-226, R-1013, R-2065, R-2181, R-2145, R-2843, R-1003, R-1410, R-2796, R-3012, R-1347, R-3136, R-1650, R-543, R-53, R-2571, R-1879, R-1738, R-2557, R-1968, R-1562, R-3067, R-788, R-1840, R-2230, R-471, R-1667, R-3165, R-361 |
| NFATC1 | up-regulates | R-2201 | -0.687031 | Pr-120 Genes (9)ANKLE2, TMEM52, YOD1, ZNF443, CDCA2, SIVA1, PSMD13, CHAMP1 Regulons (9)R-2299, R-2503, R-2342, R-546, R-2201, R-1346, R-1651, R-792, R-2963 |
| NF1 | up-regulates | R-129 | -0.687271 | Pr-55 |
| POU2F1 | up-regulates | R-72 | 0.691442 | Pr-124 Genes (20)MYPOP, DMAP1, PER1, C1S, DENND5A, TSPYL2, KNTC1, TMEM105, LRCH3, ZBTB6, CFAP73, LILRB4, TNFRSF18, LITAF, ZNF665, IPO7, KMT2B Regulons (20)R-1400, R-1425, R-1962, R-1828, R-991, R-1083, R-1577, R-72, R-2158, R-3069, R-2814, R-1149, R-1631, R-182, R-1340, R-3034, R-3139, R-39, R-199, R-593 |
| ENSG00000178860 | up-regulates | R-1100 | 0.698732 | Pr-134 Genes (104)MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1 Regulons (119)R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272 |
| KLF7 | down-regulates | R-287 | -0.699278 | Pr-28 Genes (7)PLA2G6, SFT2D1, ARL2, SLC35F6, FXYD7, FAM200B Regulons (7)R-287, R-395, R-2698, R-3055, R-1202, R-1412, R-602 |
| SPI1 | up-regulates | R-2607 | 0.699824 | Pr-134 Genes (104)MCTP1, RUVBL1, AMIGO3, HSD11B2, RHOG, FLII, TRIML2, RCC2, RAB39A, SEPHS2, ZNF467, ACBD4, SGSH, SHMT2, TRAPPC6B, C16orf72, EWSR1, SELENOF, CSF1, COPB2, ZFP90, TCN2, TARSL2, LMLN, ZBTB3, ZNF829, LAMP1, POLR3C, SESTD1, DCC, PLEKHG7, DPYD, IDO2, ZNF548, NHLRC3, MSANTD1, ARID2, KIAA0408, ZFP92, PAX5, SRGAP3, GDAP2, PDLIM7, HIST1H4C, ZNF785, ZNF786, KLHDC1, ZNF181, MYO1C, ADH5, SIRPA, HIBCH, QRICH1, ASNA1, SPRED2, HLA-DRB5, NCOA6, IPO9, LRIG2, FOXJ3, INPP5F, SELENOT, SPOUT1, PCMTD2, ZNF805, ASPDH, AKT1S1, ZBTB10, CFI, VGLL3, SCAF8, LAT, REPIN1, FBXO16, HAUS3, PPME1, DDX3X, NPEPL1, PPP3R1, C19orf73, TIAF1, PLCXD2, PISD, ARFGAP3, EIF4EBP3, TICAM2, TTC4, PCDHGA12, KIAA1147, THTPA, ZNF559-ZNF177, VBP1, PITX1, HOXD1 Regulons (119)R-396, R-2169, R-1655, R-642, R-2117, R-1267, R-2764, R-2601, R-1748, R-1705, R-2634, R-172, R-2508, R-1102, R-1707, R-1656, R-1642, R-109, R-1270, R-1933, R-207, R-454, R-1100, R-2607, R-1875, R-57, R-797, R-108, R-1730, R-1741, R-580, R-2659, R-2763, R-944, R-2160, R-100, R-2180, R-2616, R-1769, R-2996, R-1082, R-2500, R-82, R-1310, R-1008, R-1099, R-2435, R-1641, R-380, R-2224, R-2596, R-1643, R-1158, R-1646, R-205, R-899, R-1077, R-516, R-1765, R-2334, R-1066, R-163, R-1376, R-671, R-1281, R-2502, R-2810, R-1582, R-2082, R-3166, R-1004, R-2888, R-822, R-1737, R-1535, R-2748, R-2332, R-2674, R-2614, R-2682, R-1276, R-1639, R-517, R-1732, R-1011, R-1466, R-289, R-2827, R-675, R-549, R-198, R-2841, R-2825, R-2598, R-1307, R-2902, R-515, R-1676, R-103, R-2742, R-1758, R-2229, R-1652, R-1715, R-1058, R-1644, R-1018, R-1653, R-1416, R-2828, R-2670, R-1528, R-446, R-2687, R-520, R-1108, R-1970, R-2513, R-2272 |
| JUN | up-regulates | R-1186 | 0.700789 | Pr-75 |
| STAT5A | up-regulates | R-2158 | 0.702295 | Pr-124 Genes (20)MYPOP, DMAP1, PER1, C1S, DENND5A, TSPYL2, KNTC1, TMEM105, LRCH3, ZBTB6, CFAP73, LILRB4, TNFRSF18, LITAF, ZNF665, IPO7, KMT2B Regulons (20)R-1400, R-1425, R-1962, R-1828, R-991, R-1083, R-1577, R-72, R-2158, R-3069, R-2814, R-1149, R-1631, R-182, R-1340, R-3034, R-3139, R-39, R-199, R-593 |
| HBP1 | up-regulates | R-1846 | -0.703016 | Pr-117 Genes (51)LRRC25, MRPL48, CNTD1, EFCAB5, ZDHHC13, PPFIA3, TBL1XR1, IL17RA, POLR2L, KLHL28, SHARPIN, PHLDA2, IST1, SKA2, JRKL, TRMT12, WDR27, ADSSL1, SHC4, YTHDF3, ZNF267, OR2AG2, PTAR1, SLX4, PRPF40A, RABL6, ANXA4, WDR5B, MAFG, TOPORS, KCNMB2, MFAP3L, PHACTR4, TRIQK, SUPT4H1, LTC4S, DDX47, FIS1, CKLF, FAM185A, RARB, IRF4, HOXA3 Regulons (53)R-2087, R-1556, R-2707, R-342, R-2610, R-2252, R-62, R-1904, R-1388, R-1266, R-2882, R-369, R-451, R-1677, R-1495, R-1591, R-771, R-2371, R-2535, R-1846, R-945, R-500, R-986, R-2995, R-2886, R-630, R-2738, R-2991, R-1735, R-1032, R-643, R-2069, R-1485, R-2179, R-2961, R-157, R-2336, R-2142, R-2358, R-1271, R-1489, R-1734, R-2090, R-1742, R-2070, R-3168, R-2704, R-994, R-2335, R-1786, R-539, R-2068, R-1929 |
| BHLHE40 | up-regulates | R-945 | 0.704176 | Pr-117 Genes (51)LRRC25, MRPL48, CNTD1, EFCAB5, ZDHHC13, PPFIA3, TBL1XR1, IL17RA, POLR2L, KLHL28, SHARPIN, PHLDA2, IST1, SKA2, JRKL, TRMT12, WDR27, ADSSL1, SHC4, YTHDF3, ZNF267, OR2AG2, PTAR1, SLX4, PRPF40A, RABL6, ANXA4, WDR5B, MAFG, TOPORS, KCNMB2, MFAP3L, PHACTR4, TRIQK, SUPT4H1, LTC4S, DDX47, FIS1, CKLF, FAM185A, RARB, IRF4, HOXA3 Regulons (53)R-2087, R-1556, R-2707, R-342, R-2610, R-2252, R-62, R-1904, R-1388, R-1266, R-2882, R-369, R-451, R-1677, R-1495, R-1591, R-771, R-2371, R-2535, R-1846, R-945, R-500, R-986, R-2995, R-2886, R-630, R-2738, R-2991, R-1735, R-1032, R-643, R-2069, R-1485, R-2179, R-2961, R-157, R-2336, R-2142, R-2358, R-1271, R-1489, R-1734, R-2090, R-1742, R-2070, R-3168, R-2704, R-994, R-2335, R-1786, R-539, R-2068, R-1929 |
| ENSG00000054598 | up-regulates | R-1012 | -0.707501 | Pr-92 Genes (9)SVBP, AKAP5, SLC25A42, HDDC3, ZNRF1, ZNF197, TMEM222, FAM120AOS Regulons (9)R-670, R-1389, R-1063, R-2294, R-1012, R-1938, R-209, R-2697, R-162 |
| HINFP | down-regulates | R-2626 | 0.710238 | Pr-108 Genes (9)EXT1, DUSP8, TSPYL4, PSMD12, SGTB, PHB2, TMEM242, TMEM238, FOS Regulons (49)R-3052, R-2626, R-660, R-1517, R-1106, R-2339, R-3027, R-196, R-897, R-1502, R-3088, R-1284, R-1518, R-1519, R-382, R-609, R-868, R-2177, R-1424, R-875, R-2475, R-2259, R-1301, R-2105, R-2729, R-1055, R-2262, R-1214, R-2632, R-2209, R-1067, R-179, R-303, R-1689, R-2137, R-1744, R-1759, R-2761, R-1216, R-34, R-1640, R-1731, R-2363, R-502, R-2686, R-2178, R-1740, R-232, R-618 |
| PEBP1 | up-regulates | R-1757 | -0.714169 | Pr-41 Genes (9)CABP4, SFN, YES1, CSTF2T, KLHL11, DEXI, SOCS3, HIST2H2BE, ZNF248 Regulons (10)R-1382, R-479, R-1436, R-1086, R-83, R-971, R-1757, R-2378, R-3091, R-677 |
| FOXJ2 | up-regulates | R-1420 | -0.718874 | Pr-6 Genes (31)SART1, C11orf68, TALDO1, GPR150, ZNF543, COX14, ZNF571, KCTD2, PRKAG1, CSF1R, VMO1, SMDT1, SF3A3, TTC32, XPOT, KRBA2, MED12, APOBR, SDR42E1, FMNL1, ZBTB37, L3MBTL1, TRABD2A, CD55, ZNF34, DCHS2, CRIP1, NDUFA7 Regulons (31)R-46, R-2648, R-3177, R-869, R-2895, R-64, R-940, R-1917, R-3120, R-435, R-697, R-2958, R-886, R-1865, R-2783, R-1396, R-1420, R-1057, R-2768, R-2047, R-2528, R-2603, R-557, R-178, R-2874, R-70, R-2298, R-2329, R-2561, R-651, R-1845 |
| BORCS8-MEF2B | up-regulates | R-959 | -0.721458 | Pr-58 Genes (28)ZNF135, PLEKHM3, FAM220A, C3orf38, GAS1, SIAH2, GPR132, PDE4B, CDK10, PCYT2, ARHGAP30, SMIM29, FPR3, ZFP69B, C3orf62, NUGGC, FAM53B, IL1RAP, MPHOSPH8, ZNF781, NCOR2, LAMA2, ERI2, HIST1H3J, WWP2, STKLD1, MIF Regulons (28)R-386, R-1756, R-1490, R-817, R-1516, R-1342, R-2943, R-2529, R-959, R-2510, R-1213, R-578, R-641, R-2353, R-2974, R-2982, R-2054, R-833, R-2190, R-657, R-964, R-67, R-2871, R-2195, R-3076, R-2521, R-1894, R-3148 |
| MGA | down-regulates | R-1173 | 0.72466 | Pr-21 Genes (8)KMT5A, SNN, IFIT1, ZFP91, ZNF90, RPL17-C18orf32, MCRIP1, ZNF224 Regulons (13)R-1860, R-1173, R-982, R-1843, R-1409, R-2064, R-1669, R-1881, R-445, R-1837, R-476, R-1494, R-873 |
| ARID3A | down-regulates | R-1346 | 0.725791 | Pr-120 Genes (9)ANKLE2, TMEM52, YOD1, ZNF443, CDCA2, SIVA1, PSMD13, CHAMP1 Regulons (9)R-2299, R-2503, R-2342, R-546, R-2201, R-1346, R-1651, R-792, R-2963 |
| ELF3 | up-regulates | R-2145 | 0.727153 | Pr-7 Genes (38)UFSP1, SLC35G1, IMP3, R3HDM2, RNF135, HKR1, ATP6AP2, SATB1, RBM10, CRELD2, SNRNP35, ZDHHC23, AMER1, PTRHD1, NDUFA6, MAFF, PRMT3, RGPD2, ATP6V0C, C16orf54, IRS2, MKL2, FAM86B2, PRR5, ZNF33A, XRCC6, TSC22D2, SLC6A9, ADAM32, NOL4L, SERPINA1, EME2, ENTPD7, PJA2 Regulons (39)R-1139, R-308, R-1195, R-2247, R-2754, R-1584, R-1923, R-1849, R-2345, R-370, R-226, R-1013, R-2065, R-2181, R-2145, R-2843, R-1003, R-1410, R-2796, R-3012, R-1347, R-3136, R-1650, R-543, R-53, R-2571, R-1879, R-1738, R-2557, R-1968, R-1562, R-3067, R-788, R-1840, R-2230, R-471, R-1667, R-3165, R-361 |
| HMBOX1 | up-regulates | R-2378 | -0.732226 | Pr-41 Genes (9)CABP4, SFN, YES1, CSTF2T, KLHL11, DEXI, SOCS3, HIST2H2BE, ZNF248 Regulons (10)R-1382, R-479, R-1436, R-1086, R-83, R-971, R-1757, R-2378, R-3091, R-677 |
| TCF4 | down-regulates | R-2999 | 0.734651 | Pr-131 Genes (6)UBE2G2, ERC2, SLC9A8, ZNF770, MGEA5, ZNF350 Regulons (6)R-2999, R-3080, R-706, R-1303, R-79, R-1387 |
| SPI1 | up-regulates | R-2609 | -0.737744 | Pr-64 Genes (6)NT5DC1, APOO, ANKFY1, FANCM, RAB42, ZNF425 Regulons (8)R-2979, R-2609, R-7, R-1073, R-1404, R-1, R-887, R-1856 |
| KLF13 | down-regulates | R-2040 | -0.741584 | Pr-15 Genes (14)RBM33, RUFY4, SLC39A10, RPE, GLMP, MSRB1, BMPR2, SIPA1, VDAC1, EIF6, STON1, PRKDC Regulons (22)R-2088, R-2040, R-2207, R-282, R-2251, R-2946, R-1593, R-2737, R-1470, R-1848, R-1263, R-297, R-989, R-36, R-1782, R-1427, R-2049, R-2191, R-2288, R-1104, R-149, R-2959 |
| ETV5 | up-regulates | R-341 | -0.752701 | Pr-135 Genes (24)LYSMD3, MTHFR, NEB, MX2, PCBP3, CHRM5, WDR53, TOR3A, CCDC30, ZDHHC17, SLC38A3, ZNF429, PIWIL2, SLC22A5, MCMBP, PRIM1, SZT2, HNRNPUL2, CEBPD, ATXN1L, N4BP2L2, MARS2 Regulons (38)R-311, R-2304, R-610, R-973, R-901, R-2103, R-341, R-717, R-2293, R-2067, R-337, R-1454, R-979, R-1555, R-2536, R-2985, R-1455, R-2617, R-1956, R-2167, R-791, R-785, R-672, R-2847, R-2083, R-1091, R-1890, R-1299, R-1874, R-2406, R-1269, R-1942, R-389, R-2263, R-1692, R-2199, R-1523, R-1230 |
| ENSG00000245848 | up-regulates | R-1651 | 0.754573 | Pr-120 Genes (9)ANKLE2, TMEM52, YOD1, ZNF443, CDCA2, SIVA1, PSMD13, CHAMP1 Regulons (9)R-2299, R-2503, R-2342, R-546, R-2201, R-1346, R-1651, R-792, R-2963 |
| SMAD4 | up-regulates | R-2356 | 0.755167 | Pr-111 Genes (12)PARP10, ZHX2, DNHD1, MRPL54, BRI3BP, TET3, DNAJB13, CDC42SE1, RPL23A, WDHD1 Regulons (12)R-1273, R-1009, R-2956, R-2337, R-983, R-2356, R-711, R-299, R-1708, R-3092, R-2721, R-1074 |
| FOXO1 | up-regulates | R-1410 | 0.757234 | Pr-7 Genes (38)UFSP1, SLC35G1, IMP3, R3HDM2, RNF135, HKR1, ATP6AP2, SATB1, RBM10, CRELD2, SNRNP35, ZDHHC23, AMER1, PTRHD1, NDUFA6, MAFF, PRMT3, RGPD2, ATP6V0C, C16orf54, IRS2, MKL2, FAM86B2, PRR5, ZNF33A, XRCC6, TSC22D2, SLC6A9, ADAM32, NOL4L, SERPINA1, EME2, ENTPD7, PJA2 Regulons (39)R-1139, R-308, R-1195, R-2247, R-2754, R-1584, R-1923, R-1849, R-2345, R-370, R-226, R-1013, R-2065, R-2181, R-2145, R-2843, R-1003, R-1410, R-2796, R-3012, R-1347, R-3136, R-1650, R-543, R-53, R-2571, R-1879, R-1738, R-2557, R-1968, R-1562, R-3067, R-788, R-1840, R-2230, R-471, R-1667, R-3165, R-361 |
| SPI1 | up-regulates | R-2606 | -0.759833 | Pr-14 Genes (17)TMEM70, TUBB6, PNMA1, CASKIN2, ANXA2R, MLF1, ARID3B, SLC17A8, FZD2, PLAG1, SLC8A1, SEMA4B, NOXA1, AKR1C3, MPV17L2 Regulons (18)R-1002, R-1429, R-1659, R-894, R-77, R-1832, R-1545, R-184, R-2284, R-2223, R-2075, R-2878, R-2606, R-1398, R-2952, R-1932, R-3170, R-2014 |
| FOXJ2 | up-regulates | R-1431 | 0.765091 | Pr-16 Genes (20)NR2C2, LOC653513, C11orf54, ZNRF3, NSMCE3, LRRC70, TAF9B, B3GLCT, ZNF775, PPTC7, TRIM33, SIPA1L1, ZNF460, ZNF790, ZKSCAN8, CEP290, CIPC, GIMAP1, LILRA6, CHMP4A Regulons (20)R-383, R-191, R-50, R-872, R-1431, R-1919, R-1532, R-1546, R-2884, R-84, R-2290, R-666, R-1935, R-3128, R-1871, R-2949, R-2227, R-156, R-1279, R-2522 |
| ELK1 | up-regulates | R-648 | 0.765153 | Pr-99 Genes (28)GNG7, ZBTB34, APOBEC3B, PSMG4, HSF1, PRPF39, ARL15, CERKL, MSL1, ZNF79, PLXNB2, YTHDF2, TLK1, TSEN15, CAPZA2, FCGR3A, LIME1, SMIM5, C6orf47, DENND6B, LIN52, RBMXL1, EMP2, TMEM167B, ZSCAN31, CDRT4 Regulons (31)R-3174, R-453, R-1770, R-3083, R-1212, R-648, R-2506, R-2709, R-1696, R-2314, R-2642, R-587, R-492, R-1891, R-3063, R-640, R-2162, R-3070, R-1834, R-188, R-2140, R-2317, R-1435, R-3129, R-699, R-3090, R-650, R-1007, R-2844, R-2311, R-606 |
| SOX4 | down-regulates | R-2189 | -0.776926 | Pr-12 Genes (14)CDK5R1, C18orf32, ARL6IP4, NELFA, INTS5, TCEAL9, ZNF431, ZNF81, FAM49A, ARMH1, C2CD4A, GIGYF2, SPIRE2, TMA7 Regulons (17)R-776, R-1187, R-3181, R-555, R-2154, R-2189, R-1434, R-189, R-3127, R-2242, R-1403, R-281, R-2291, R-2193, R-1033, R-1861, R-2245 |
| FOSL1 | up-regulates | R-2796 | 0.780203 | Pr-7 Genes (38)UFSP1, SLC35G1, IMP3, R3HDM2, RNF135, HKR1, ATP6AP2, SATB1, RBM10, CRELD2, SNRNP35, ZDHHC23, AMER1, PTRHD1, NDUFA6, MAFF, PRMT3, RGPD2, ATP6V0C, C16orf54, IRS2, MKL2, FAM86B2, PRR5, ZNF33A, XRCC6, TSC22D2, SLC6A9, ADAM32, NOL4L, SERPINA1, EME2, ENTPD7, PJA2 Regulons (39)R-1139, R-308, R-1195, R-2247, R-2754, R-1584, R-1923, R-1849, R-2345, R-370, R-226, R-1013, R-2065, R-2181, R-2145, R-2843, R-1003, R-1410, R-2796, R-3012, R-1347, R-3136, R-1650, R-543, R-53, R-2571, R-1879, R-1738, R-2557, R-1968, R-1562, R-3067, R-788, R-1840, R-2230, R-471, R-1667, R-3165, R-361 |
| TGIF1 | up-regulates | R-2506 | -0.780236 | Pr-99 Genes (28)GNG7, ZBTB34, APOBEC3B, PSMG4, HSF1, PRPF39, ARL15, CERKL, MSL1, ZNF79, PLXNB2, YTHDF2, TLK1, TSEN15, CAPZA2, FCGR3A, LIME1, SMIM5, C6orf47, DENND6B, LIN52, RBMXL1, EMP2, TMEM167B, ZSCAN31, CDRT4 Regulons (31)R-3174, R-453, R-1770, R-3083, R-1212, R-648, R-2506, R-2709, R-1696, R-2314, R-2642, R-587, R-492, R-1891, R-3063, R-640, R-2162, R-3070, R-1834, R-188, R-2140, R-2317, R-1435, R-3129, R-699, R-3090, R-650, R-1007, R-2844, R-2311, R-606 |
| TRAF4 | up-regulates | R-3033 | -0.781484 | Pr-0 Genes (84)GPX2, BNIP3, METRNL, PUS1, SAMD12, CD163, SLC25A20, EFCAB13, EXOSC4, SAMD4B, CATSPERE, C14orf119, ARHGAP45, BBS12, EHMT1, SETD2, ZBTB20, RFX7, TSKU, SRPRA, SLC25A10, ASB7, UPP1, LIN9, CCR10, ZFP1, USP18, TNFAIP2, CDNF, SOCS1, METTL7A, PDE6G, SP1, P4HB, DRG1, CXorf38, MORF4L1, AIDA, WWOX, SAPCD2, PPP1CC, SPIN4, CXCR3, ZNF397, TPCN1, CMC1, GCNT1, FNBP1, RSBN1L, LOC100288637, TMPPE, ZC3H6, ZNF669, NANOS1, ALKBH2, JPT1, LIN54, HLA-DRB1, ZNF493, EPHB4, TRAPPC2B, SIAH1, ESRRG, TCF4, SERTAD1, ZNF398, ZNF257, ATG7, MPEG1, RPS4X, PNP, HMGN2, HIST2H2BF, COLQ, RPS29 Regulons (86)R-180, R-2076, R-2157, R-3164, R-3147, R-338, R-2156, R-2409, R-885, R-941, R-1192, R-556, R-3197, |