Program

Program 116

Genes (3)

CLCF1, RDH14,

Regulons (3)

R-1217, R-1537, R-3195

Causal Mechanistic Flows with regulons in program Pr-116

MutationRoleRegulatorRoleRegulonHazard Ratio# regulon genesTranscriptional Program
FGFR3up-regulatesTEAD1activatesR-1217-0.009247217Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

GPR98down-regulatesTEAD1activatesR-1217-0.009247217Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

KDM3Bdown-regulatesTEAD1activatesR-1217-0.009247217Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

LTBup-regulatesTEAD1activatesR-1217-0.009247217Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

t(11;14)down-regulatesTEAD1activatesR-1217-0.009247217Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

RNASeq_FGFR3_Callup-regulatesTEAD1activatesR-1217-0.009247217Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

RNASeq_MAFB_Calldown-regulatesTEAD1activatesR-1217-0.009247217Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

t(14;16)down-regulatesTEAD1activatesR-1217-0.009247217Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

t(4;14)up-regulatesTEAD1activatesR-1217-0.009247217Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

t(11;14)_cytogeneticdown-regulatesTEAD1activatesR-1217-0.009247217Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

t(4;14)_cytogeneticup-regulatesTEAD1activatesR-1217-0.009247217Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

NRASdown-regulatesBBXactivatesR-1537-2.087056Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

RNASeq_CCND2_Calldown-regulatesBBXactivatesR-1537-2.087056Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

RNASeq_MAFA_Callup-regulatesBBXactivatesR-1537-2.087056Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

t(14;16)up-regulatesBBXactivatesR-1537-2.087056Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

IRF4down-regulatesNR3C1activatesR-3195-2.1416Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

KIAA1244up-regulatesNR3C1activatesR-3195-2.1416Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

MYO10up-regulatesNR3C1activatesR-3195-2.1416Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

NFKB2up-regulatesNR3C1activatesR-3195-2.1416Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

NRASdown-regulatesNR3C1activatesR-3195-2.1416Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

t(11;14)down-regulatesNR3C1activatesR-3195-2.1416Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

RNASeq_CCND2_Calldown-regulatesNR3C1activatesR-3195-2.1416Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

RNASeq_MAFA_Callup-regulatesNR3C1activatesR-3195-2.1416Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

t(14;16)up-regulatesNR3C1activatesR-3195-2.1416Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

t(11;14)_cytogeneticdown-regulatesNR3C1activatesR-3195-2.1416Pr-116

Genes (3)

CLCF1, RDH14

Regulons (3)

R-1217, R-1537, R-3195

Regulons in program Pr-116

Regulon Cox Hazard Ratio # genes # causal flows
R-1217-0.00924721711
R-1537-2.0870564
R-3195-2.141610

Genes in program Pr-116

EnsEMBL IdEntrez IdPreferred
ENSG00000175505 23529CLCF1
ENSG00000240857 57665RDH14
ENSG00000243710

Program Survival Plots

Kaplan-Meier curves demonstrating the sub-stratification of clinical subtypes based upon the network activity of the most predictive individual or pair of genes as determined by the LASSO predictions