Program

Causal Mechanistic Flows with regulons in program Pr-0

MutationRoleRegulatorRoleRegulonHazard Ratio# regulon genesTranscriptional Program
AHNAK2down-regulatesIRF1activatesR-180-0.084845335Pr-0
KRASup-regulatesIRF1activatesR-180-0.084845335Pr-0
NRASup-regulatesIRF1activatesR-180-0.084845335Pr-0
t(11;14)up-regulatesIRF1activatesR-180-0.084845335Pr-0
RNASeq_FGFR3_Callup-regulatesIRF1activatesR-180-0.084845335Pr-0
t(11;14)_cytogeneticup-regulatesIRF1activatesR-180-0.084845335Pr-0
BRAFup-regulatesPRDM1activatesR-20760.10219521Pr-0
NEBdown-regulatesPRDM1activatesR-20760.10219521Pr-0
del13up-regulatesPRDM1activatesR-20760.10219521Pr-0
del17down-regulatesPRDM1activatesR-20760.10219521Pr-0
NEBdown-regulatesGMEB2activatesR-21570.1050686Pr-0
NEBdown-regulatesHSF2activatesR-3164-0.1519398Pr-0
amp1qup-regulatesHSF2activatesR-3164-0.1519398Pr-0
del13up-regulatesHSF2activatesR-3164-0.1519398Pr-0
AHNAK2down-regulatesE4F1activatesR-3147-0.19086810Pr-0
MACF1down-regulatesE4F1activatesR-3147-0.19086810Pr-0
MYO10down-regulatesE4F1activatesR-3147-0.19086810Pr-0
NEBdown-regulatesE4F1activatesR-3147-0.19086810Pr-0
t(11;14)up-regulatesE4F1activatesR-3147-0.19086810Pr-0
RNASeq_MAFA_Calldown-regulatesE4F1activatesR-3147-0.19086810Pr-0
t(4;14)up-regulatesE4F1activatesR-3147-0.19086810Pr-0
SYNE1down-regulatesE4F1activatesR-3147-0.19086810Pr-0
t(11;14)_cytogeneticup-regulatesE4F1activatesR-3147-0.19086810Pr-0
t(11;14)up-regulatesETV5activatesR-338-0.23709317Pr-0
RNASeq_MAFA_Calldown-regulatesETV5activatesR-338-0.23709317Pr-0
SYNE1down-regulatesETV5activatesR-338-0.23709317Pr-0
del13up-regulatesETV5activatesR-338-0.23709317Pr-0
ASXL3down-regulatesGMEB2activatesR-2156-0.2374829Pr-0
MAGI1down-regulatesGMEB2activatesR-2156-0.2374829Pr-0
NEBdown-regulatesGMEB2activatesR-2156-0.2374829Pr-0
TACC2down-regulatesGMEB2activatesR-2156-0.2374829Pr-0
amp1qup-regulatesGMEB2activatesR-2156-0.2374829Pr-0
del13up-regulatesGMEB2activatesR-2156-0.2374829Pr-0
AHNAK2down-regulatesATF3activatesR-2409-0.3131525Pr-0
MYO10down-regulatesATF3activatesR-2409-0.3131525Pr-0
PTPRDdown-regulatesATF3activatesR-2409-0.3131525Pr-0
RNASeq_FGFR3_Callup-regulatesATF3activatesR-2409-0.3131525Pr-0
t(4;14)up-regulatesATF3activatesR-2409-0.3131525Pr-0
SYNE1down-regulatesATF3activatesR-2409-0.3131525Pr-0
TP53down-regulatesATF3activatesR-2409-0.3131525Pr-0
DNAH5down-regulatesTFEBactivatesR-885-0.33690911Pr-0
MYO10down-regulatesTFEBactivatesR-885-0.33690911Pr-0
NEBdown-regulatesTFEBactivatesR-885-0.33690911Pr-0
t(11;14)up-regulatesTFEBactivatesR-885-0.33690911Pr-0
RNASeq_FGFR3_Callup-regulatesTFEBactivatesR-885-0.33690911Pr-0
t(4;14)up-regulatesTFEBactivatesR-885-0.33690911Pr-0
t(14;16)_cytogeneticdown-regulatesTFEBactivatesR-885-0.33690911Pr-0
MAGI1down-regulatesBHLHE40activatesR-9410.3379979Pr-0
NEBdown-regulatesBHLHE40activatesR-9410.3379979Pr-0
t(11;14)up-regulatesBHLHE40activatesR-9410.3379979Pr-0
SYNE1down-regulatesBHLHE40activatesR-9410.3379979Pr-0
AHNAK2down-regulatesFOXK1activatesR-1192-0.35373632Pr-0
ASXL3down-regulatesFOXK1activatesR-1192-0.35373632Pr-0
MAGI1down-regulatesFOXK1activatesR-1192-0.35373632Pr-0
MYO10down-regulatesFOXK1activatesR-1192-0.35373632Pr-0
NEBdown-regulatesFOXK1activatesR-1192-0.35373632Pr-0
PTPRDdown-regulatesFOXK1activatesR-1192-0.35373632Pr-0
RNASeq_MAFA_Calldown-regulatesFOXK1activatesR-1192-0.35373632Pr-0
t(4;14)up-regulatesFOXK1activatesR-1192-0.35373632Pr-0
SYNE1down-regulatesFOXK1activatesR-1192-0.35373632Pr-0
TACC2down-regulatesFOXK1activatesR-1192-0.35373632Pr-0
amp1qup-regulatesFOXK1activatesR-1192-0.35373632Pr-0
del13up-regulatesFOXK1activatesR-1192-0.35373632Pr-0
AHNAK2down-regulatesTFE3activatesR-556-0.37868812Pr-0
NEBdown-regulatesTFE3activatesR-556-0.37868812Pr-0
RNASeq_FGFR3_Callup-regulatesTFE3activatesR-556-0.37868812Pr-0
t(4;14)up-regulatesTFE3activatesR-556-0.37868812Pr-0
amp1qup-regulatesTFE3activatesR-556-0.37868812Pr-0
del13up-regulatesTFE3activatesR-556-0.37868812Pr-0
AHNAK2up-regulatesMLXrepressesR-3197-0.40762410Pr-0
ANK2up-regulatesMLXrepressesR-3197-0.40762410Pr-0
MYO10up-regulatesMLXrepressesR-3197-0.40762410Pr-0
NEBup-regulatesMLXrepressesR-3197-0.40762410Pr-0
PTPRDup-regulatesMLXrepressesR-3197-0.40762410Pr-0
RNASeq_MAFA_Callup-regulatesMLXrepressesR-3197-0.40762410Pr-0
RNASeq_MAFB_Callup-regulatesMLXrepressesR-3197-0.40762410Pr-0
SYNE1up-regulatesMLXrepressesR-3197-0.40762410Pr-0
TACC2up-regulatesMLXrepressesR-3197-0.40762410Pr-0
t(14;16)_cytogeneticup-regulatesMLXrepressesR-3197-0.40762410Pr-0
AHNAK2down-regulatesNFKB1activatesR-1572-0.44509152Pr-0
FAT3down-regulatesNFKB1activatesR-1572-0.44509152Pr-0
MACF1down-regulatesNFKB1activatesR-1572-0.44509152Pr-0
MAGI1down-regulatesNFKB1activatesR-1572-0.44509152Pr-0
MYO10down-regulatesNFKB1activatesR-1572-0.44509152Pr-0
PCDH10down-regulatesNFKB1activatesR-1572-0.44509152Pr-0
PTPRDdown-regulatesNFKB1activatesR-1572-0.44509152Pr-0
RNASeq_CCND2_Calldown-regulatesNFKB1activatesR-1572-0.44509152Pr-0
TACC2down-regulatesNFKB1activatesR-1572-0.44509152Pr-0
DCHS1down-regulatesENSG00000054598activatesR-999-0.47812737Pr-0
MAGI1down-regulatesENSG00000054598activatesR-999-0.47812737Pr-0
NEBdown-regulatesENSG00000054598activatesR-999-0.47812737Pr-0
PTPRDdown-regulatesENSG00000054598activatesR-999-0.47812737Pr-0
t(11;14)up-regulatesENSG00000054598activatesR-999-0.47812737Pr-0
del17down-regulatesENSG00000054598activatesR-999-0.47812737Pr-0
t(14;16)_cytogeneticdown-regulatesENSG00000054598activatesR-999-0.47812737Pr-0
ASXL3down-regulatesELK1activatesR-6360.48545220Pr-0
MAGI1down-regulatesELK1activatesR-6360.48545220Pr-0